期刊
TRENDS IN PLANT SCIENCE
卷 14, 期 5, 页码 264-269出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tplants.2009.03.002
关键词
-
资金
- Spanish granting agency Direccion General de Investigacion Cientifica y Tecnica [BIO2008-03528]
- Generalitat Valenciana [GV05-238]
- Consejo Superior de Investigaciones Cientificas
- Ministry of Science and Innovation
Of all known plant pathogens, viroids have the lowest biological complexity. Their genome consists of a naked RNA without protein-encoding capacity. However, viroids contain sufficient genetic information to establish infection in susceptible hosts. The process by which this tiny RNA subverts the plant cell machinery by coercing the host to express symptoms of viroid infection is the 'Holy Grail' that has been searched for since the first viroid-induced disease was described. Recently, a large body of evidence has led to the emergent view that RNA silencing has a crucial role in viroid pathogenesis and evolution. Here, we chronologically analyse the relevant findings supporting this idea and propose a model to explain the possible interrelation between the transacting small interfering RNA (ta-siRNA) biogenesis pathway and viroid replication and pathogenesis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据