期刊
TRENDS IN MOLECULAR MEDICINE
卷 19, 期 2, 页码 71-73出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.molmed.2012.10.006
关键词
microRNA; biomarker; cancer therapy
资金
- National Basic Research program of China [2012CB517500]
- National Natural Science Foundation of China [31000585, 81001481]
The roles of circulating miRNAs in disease therapy remain largely unclear, but recent data suggests a role for these molecules in cancer. In patients with cancer, the levels of circulating miRNAs with tumor-suppressing capabilities increase and those with oncogenic activity decrease. In addition, the population of circulating miRNAs correlates highly with immune response, suggesting that circulating miRNAs could be driving anticancer effects through active immune defense and might be a novel strategy for cancer therapy.
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