期刊
TRENDS IN CARDIOVASCULAR MEDICINE
卷 24, 期 3, 页码 105-112出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcm.2013.09.002
关键词
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资金
- National Institutes of Health [HL091076, HL115141, HL117994]
- Watkins Cardiovascular Medicine Discovery Award
- Jonathan Levy Research Fund
The microRNA family, miR-181, plays diverse roles in regulating key aspects of cellular growth, development, and activation. Accumulating evidence supports a central role for the miR-181 family in vascular inflammation by controlling critical signaling pathways, such as downstream NF-kappa B signaling, and targets relevant to endothelial cell activation and immune cell homeostasis. This review examines the current knowledge of the miR-181 family's role in key cell types that critically control cardiovascular inflammation under pathological and physiological stimuli. Crown Copyright (C) 2013 Published by Elsevier Inc. All rights reserved.
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