期刊
TRENDS IN CARDIOVASCULAR MEDICINE
卷 22, 期 4, 页码 88-92出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcm.2012.07.001
关键词
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资金
- Region Pays de la Loire (CIMATH-2)
- INSERM
- Universite d'Angers
- Conseil Regional des Pays de la Loire
Microparticles are a heterogeneous group of membrane-coated vesicles that can act as signaling elements in the inflammatory processes. Once released from cells by membrane blebbing, microparticles become efficient vectors that exchange biological information between cells. Detectable in small amounts in peripheral blood of healthy individuals, elevated concentrations of microparticles originating from platelet, leukocyte, erythrocyte, and endothelial lineages are associated with a variety of pathophysiological conditions, including thrombosis, inflammation, sepsis, and metabolic disorders. This review summarizes the role of microparticles in modulating inflammation during cardiovascular diseases. (Trends Cardiovasc Med 2012;22:88-92) (C) 2012 Elsevier Inc. All rights reserved.
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