Review
Microbiology
Guillaume Tahon, Patricia Geesink, Thijs J. G. Ettema
Summary: The discovery and study of Archaea in the past few decades have greatly expanded our understanding of their cell biology, physiology, ecology, and diversity. However, due to computational limitations and the ongoing discovery of new lineages, a stable archaeal phylogeny has not yet been achieved. Therefore, obtaining consensus on the phylogenetic and taxonomic classification of Archaea should be a high priority for the research community.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 75, 2021
(2021)
Article
Fisheries
Wagner C. Valenti, Helenice P. Barros, Patricia Moraes-Valenti, Guilherme W. Bueno, Ronaldo O. Cavalli
Summary: Aquaculture in Brazil has a long history, with freshwater fish and marine shrimp being the main products produced. The industry is dominated by small farms and faces the challenge of developing sustainable production systems and leveraging new technologies and innovations to support its growth.
AQUACULTURE REPORTS
(2021)
Review
Clinical Neurology
Hulya Ulugut, Yolande A. L. Pijnenburg
Summary: This study explores the historical roots of frontotemporal dementia (FTD), dating back to the 19th century, and recognizes it as a distinct neurological entity only a few decades ago. The methods include qualitative study and literature review, providing an overview of FTD's historical background, birth, evolution, and future directions. The results indicate that recognition of FTD was hindered by various factors such as rigid perceptions of dementia, division between neurology and psychiatry, limited neuroimaging capabilities, and lack of pathological proof.
ALZHEIMERS & DEMENTIA
(2023)
Review
Behavioral Sciences
Brian A. Anderson, Haena Kim, Andy J. Kim, Ming-Ray Liao, Lana Mrkonja, Andrew Clement, Laurent Gregoire
Summary: The proposal of selection history as a distinct mechanism of attentional control marks a revolution in attention research, replacing a theoretical dichotomy with a trichotomy. This new mechanism is multifaceted, with different components shaped by various learning experiences such as reward and past experience. Relationships between these components are explored in depth, leading to an integrative account centered on underlying themes.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Clinical Neurology
Shabal Sapkota, Suman Rijal, Mitesh Karn
Summary: Neurosurgery in Nepal has a long history, with modern services starting after 1990. Despite progress, there is still a lack of qualified neurosurgeons. The next steps involve strengthening the geographical dissemination of neurosurgical care in Nepal, reassessing training programs, and promoting subspecialty practices in neurosurgery.
WORLD NEUROSURGERY
(2022)
Review
Chemistry, Multidisciplinary
Ke Li, Craig M. Crews
Summary: PROTACs are a type of molecules with novel event-driven mechanism, offering multiple advantages over traditional inhibitors, such as catalytic nature and targeted protein degradation, which may lead to improved therapeutic outcomes with reduced toxicity. However, further research and development efforts are needed to fully explore their potential.
CHEMICAL SOCIETY REVIEWS
(2022)
Review
Pharmacology & Pharmacy
Jennifer N. Hennigan, Michael D. Lynch
Summary: Enzyme-based therapeutics have the potential to tap into vast enzyme biodiversity and treat various conditions, but face challenges in the development of new therapies, including overcoming technical barriers.
DRUG DISCOVERY TODAY
(2022)
Article
Biochemical Research Methods
Jonathan W. Yewdell
Summary: In the past 35 years, significant progress has been made in the study of immunopeptidome, revealing the importance of short peptides binding to major histocompatibility complex in T-cell recognition. This article discusses the contribution of proteasome-mediated splicing to immunopeptidome and the recent findings linking immunopeptidome to the translatome revealed by ribosome profiling. It also emphasizes the need to attract talented young scientists to further advance antigen-processing research, which has seen remarkable success in T-cell-based cancer immunotherapy.
MOLECULAR & CELLULAR PROTEOMICS
(2022)
Review
Materials Science, Multidisciplinary
Joseph Rich, Zhenhua Tian, Tony Jun Huang
Summary: The research in intracellular delivery technologies has surged with the advancement in cell-based therapies and reprogramming. Physical cell membrane permeabilization techniques, especially sonoporation, show promise in delivering functional cargos to various cells, but bubble-based methods may have limitations such as requiring contrast agents and potential damage to cell components. Development of non-bubble-based sonoporation mechanisms aims to overcome these limitations and improve intracellular delivery efficiency.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Review
Chemistry, Multidisciplinary
Wentao Jiang, Ziyu Wu, Zheng Gao, Mimi Wan, Min Zhou, Chun Mao, Jian Shen
Summary: Artificial cells are constructed to imitate natural cells and can be used for studying biological processes and the origin of life. They can be endowed with various functions through the incorporation of proteins and genes, and have great potential in therapeutic applications.
Review
Psychology, Multidisciplinary
Eugen Dimant, Shaul Shalvi
Summary: Achieving successful behavior change through nudging is challenging, especially when trying to change behavior that is collectively harmful but individually beneficial. Meta-nudging offers a promising approach by indirectly nudging end-users through social influencers.
CURRENT OPINION IN PSYCHOLOGY
(2022)
Review
Chemistry, Medicinal
Yasuhiro Nishida, Pernilla Christina Berg, Behnaz Shakersain, Karen Hecht, Akiko Takikawa, Ruohan Tao, Yumeka Kakuta, Chiasa Uragami, Hideki Hashimoto, Norihiko Misawa, Takashi Maoka
Summary: This review article provides a comprehensive exploration of the history, chemical and physical attributes, distribution, and biosynthesis of astaxanthin (AX). It also delves into the health benefits, biofunctional characteristics, and market status of AX, aiming to provide a robust foundation for future scientific endeavors addressing societal needs for sustainable nutritional and medicinal solutions.
Review
Pharmacology & Pharmacy
Mia Karam, Georges Daoud
Summary: mRNA vaccines have emerged as promising alternative platforms to conventional vaccines with advantages such as easy production, low cost, high safety profile, and potent effectiveness, especially during pandemics. Recent advancements in nanotechnology have enhanced mRNA stability and delivery through novel delivery systems such as lipid nanoparticles. Studies have shown the advantages of adopting mRNA vaccines for viral diseases and cancer in animal and human studies. Self-amplifying mRNA is considered the next generation of mRNA vaccines.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Surgery
Hui-Yun Cheng, Chih-Fan Lin, Madonna Rica Anggelia, Ping-Chin Lai, Ling-Yi Shih, Shiao-Chin Liu, Fu-Chan Wei, Cheng-Hung Lin
Summary: This study evaluated the outcome of VCA surgery on reciprocal rodent donor-recipient combinations and found that the same immunosuppression regimen produced different results in different donor-recipient combinations. Modification of the model and immunosuppression regimen is needed based on the results.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Review
Plant Sciences
Ian Max Moller, Allan G. Rasmusson, Olivier Van Aken
Summary: The study of plant mitochondria began in the 1950s, focusing on establishing basic properties and unique characteristics compared to mammalian mitochondria. With advancements in molecular biology and genomics, further unique features were discovered, including the large size of plant mtDNA, unique mRNA maturation process, and a large proteome with many unique proteins.
