Article
Chemistry, Applied
Dina A. Tolan, Tahani Kashar, Kazunari Yoshizawa, Ahmed M. El-Nahas
Summary: A novel hydrazide-hydrazone ligand derived from isonicotinic acid was synthesized and seven mononuclear complexes with Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II) were prepared and characterized. DFT studies were conducted to investigate the structures of the ligand and its complexes. The antimicrobial activities of the ligand and its complexes were compared, with the Hg(II) complex showing the best antibacterial and antifungal activity among all tested complexes.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Medicinal
Fatima Doganc, Ismail Celik, Gokcen Eren, Marcel Kaiser, Reto Brun, Hakan Goker
Summary: A series of monocationic new guanidinobenzimidazole derivatives were synthesized and evaluated for their antiparasitic activity against four parasites in vitro. Two compounds showed promising activity against P. Falciparum, and molecular docking studies were conducted to understand the interactions between DNA minor groove and these compounds. All compounds exhibited theoretical ADME profiles conforming to Lipinski's and Ghose's restrictive rules.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Leriman Zeybel, Dursun Ali Kose
Summary: Rare earth metal cations (Eu3+, Tb3+, HO3+, Er3+ and Yb3+) were synthesized with the acesulfame ligand using hydrothermal method. Structural characterization of the compounds was done using elemental analysis, infrared spectroscopy, mass analysis, solid-state UV-vis spectroscopy, and TGA curves, revealing a sixteen-coordination structure with one hydrate water. The thermal decomposition of the complex structures formed metal oxides as products, as determined by FT-IR analysis.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Physical
Basma A. Ismail, Doaa A. Nassar, Zeinab H. Abd El-Wahab, Omyma A. M. Ali
Summary: Novel Schiff base ligand N1,N2-bis(furan-2-ylmethylene)-4-methylbenzene-1,2-diamine (L) and its metal complexes were synthesized and characterized using various spectroscopic techniques. The metal complexes showed different properties such as electrolytic nature, geometry, and optical band gap energy, and exhibited photocatalytic properties for methylene blue degradation. The Cd(II) complex displayed higher antimicrobial activity and cytotoxicity against human liver carcinoma cells compared to the ligand and reference drugs.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Gajanan Dongare, Anand Aswar
Summary: A new Schiff base hydrazone ligand H2L was synthesized and used to form complexes with chloride salts of Cr(III), Mn(II), Fe(III), Co(II), Ni(II), and Cu(II). Characterization of the ligand and complexes was done through various analyses, showing different coordination modes and geometries for the complexes. The metal complexes exhibited enhanced antibacterial activity compared to the parent ligand.
JOURNAL OF SAUDI CHEMICAL SOCIETY
(2021)
Article
Chemistry, Applied
Asmaa M. Fahim, Hend S. Magar, Manara A. Ayoub
Summary: In this study, the structure and molecular properties of a triazole-thiol derivative and its metal complexes were investigated. The physicochemical analysis confirmed the formation of stable metal complexes, and their thermal cracking behavior was evaluated. The FT-IR spectra indicated chelation of the triazole-thiol ligand in the complexes. Antimicrobial evaluation showed that the metal complexes had higher activity compared to the ligand. Theoretical docking simulation and electrochemical analysis provided insights into the interactions and properties of the complexes.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Mona A. Alhasani, Thoraya A. Farghaly, Hoda A. El-Ghamry
Summary: Metal complexes of Cu(II), Ni(II), Co(II) and Mn(II) with the ligand ACHP have been synthesized and characterized using various analytical and spectroscopic techniques. The molecular structures, geometries, and formulas of the complexes have been determined, with UV-Vis spectra and magnetic moment measurements providing insights into the coordination geometry around the metal ions.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Inorganic & Nuclear
Robin Bolliger, Olivier Blacque, Henrik Braband, Roger Alberto
Summary: The oxidation of [Re(NCCH3)(6)](2+) with the thinathrene radical cation leads to the formation of [Re(NCCH3)(6)](3+), which is a fully solvated +3 complex. This complex demonstrates a faster CH3CN exchange rate, making it a suitable precursor for new Rem complexes.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Robin Bolliger, Olivier Blacque, Henrik Braband, Roger Alberto
Summary: Oxidation of [Re(NCCH3)6]2+ with the thianthrene radical cation results in the formation of [Re(NCCH3)6]3+, a fully solvated +3 complex. It exhibits faster CH3CN exchange and can be used as a versatile precursor for ReIII chemistry.
INORGANIC CHEMISTRY
(2022)
Article
Polymer Science
M. Ali Aboudzadeh, Vanessa Rodriguez-Fanjul, Alessio Terenzi, Estibaliz Gonzalez de San Roman, Jose I. Miranda, Ana M. Pizarro, Luca Salassa, Fabienne Barroso-Bujans
Summary: We synthesized a macrocyclic poly(ethyleneoxide) (PEO) connected with a [Ru(bpy)(3)](2+) unit, which is a photoactive metal complex with potential biomedical applications. The PEO chain provides biocompatibility, water solubility, and topological play. The macrocycles were successfully synthesized by copper-free click cycloaddition and exhibited higher fluorescence lifetime compared to their linear analogues.
Article
Chemistry, Physical
S. G. Nozha, Sh M. Morgan, S. E. Abu Ahmed, M. A. El-Mogazy, M. A. Diab, A. Z. El-Sonbati, M. Abou-Dobara
Summary: In this study, metal polymer complexes of N,N'-1,4-phenylene have been synthesized and characterized using various analytical techniques. The ligand and polymer complex exhibited strong antibacterial activity against Staphylococcus aureus, with molecular docking revealing excellent binding with the receptor of Staphylococcus aureus compared to E. coli.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Physical
Heba Magdy Kamal, Hassan Abdelfattah El-Sayed, Sadeek Atia Sadeek, Wael Abd-Allah Zordok, Mohamed Saeed El-Attar
Summary: Six mixed ligand metal complexes were synthesized by the interaction of Cr(III), Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) with 1-[4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl]ethanone (L) in the presence of 2,20-bipyridine (Bipy). The compounds were characterized by elemental analyses, FT-IR, UV-vis, 1H NMR spectra, thermal analyses (TG-DTG and DTA), X-ray powder diffraction (XRD), molar conductance, and magnetic moment. The complexes showed bidentate bonding of L through nitrogen and sulfur atoms and coordination of Bipy through nitrogen atoms. The complexes exhibited octahedral geometry and were found to have potential antimicrobial activity.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Pharmacology & Pharmacy
Klaudia Cseh, Heiko Geisler, Kristina Stanojkovska, Julia Westermayr, Philipp Brunmayr, Dominik Wenisch, Natalie Gajic, Michaela Hejl, Martin Schaier, Gunda Koellensperger, Michael A. A. Jakupec, Philipp Marquetand, Wolfgang Kandioller
Summary: The main purpose of this study was to synthesize a new set of naphthoquinone-based ruthenium(II) arene complexes and understand their mode of action. The chemical structures and biological activities of these compounds were examined, and a positive correlation was found between cytotoxicity, lipophilicity, and cellular accumulation. This study provides important insights into the effects of these arene complexes.
Article
Crystallography
Andrea Pastrana-Davila, Gianella Minotta, Javier Ellena, Pedro H. O. Santiago, Richard F. D'Vries
Summary: This study presents the synthesis and characterization of two new coordination compounds of metformin and transition metals. The cobalt compound [Co(Met)(3)][CoCl4]Cl·3H2O consists of a cationic Co(III) octahedral unit and anionic Co(II) tetrahedral subunits. The copper compound [(Cu(Met)Cl)(2)-μ-Cl-2] is a dimeric complex with bridging chloride anions, forming shared-edge square pyramidal units.
Article
Chemistry, Applied
Ahmed E. Salem, Soha F. Mohammed, Sadeek A. Sadeek, Wael A. Zordok, Mohamed S. El-Attar
Summary: Four mixed ligand metal complexes derived from the interaction of Cu(II), Zn(II), Zr(IV), and Cd(II) with antihistamine cetirizine were synthesized and characterized. The complexes exhibited excellent thermal stability and biological activity, suggesting their potential as bactericides.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Athandwe M. Paca, Peter A. Ajibade, Fartisincha P. Andrew, Nirasha Nundkumar, Moganavelli Singh
Summary: The study synthesized and characterized four palladium complexes with high to moderate potency against human cell lines. Two of the complexes were very effective against the three cell lines, while the other two had slightly lower anticancer efficacy.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Abimbola E. Oluwalana, Peter A. Ajibade
Summary: Tin sulfide nanoparticles were successfully prepared from single source precursors and utilized as efficient photocatalysts for the degradation of various dyes under visible light irradiation. The results demonstrated the effectiveness of the SnS nanoparticles in degrading organic dyes, with high degradation efficiencies observed for brilliant green, crystal violet, methylene blue, and methyl red dyes. Liquid chromatography-mass spectrometry was used to investigate the degradation pathway, while the impact of irradiation time, scavengers, and photostability on the photocatalysis process was also evaluated.
JOURNAL OF SULFUR CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
P. A. Ajibade, N. Solomane, B. M. Sikakane
Summary: The paper presents the preparation, morphological characterization, and photocatalytic performance of zinc sulfide nanoparticles synthesized from zinc(II) dithiocarbamate precursors. The results demonstrate the nanoparticles' effectiveness in degrading methylene blue dye.
CHALCOGENIDE LETTERS
(2022)
Review
Biochemistry & Molecular Biology
Peter A. Ajibade, Solomon O. Oloyede
Summary: This article explores various synthetic strategies of metal-organic frameworks (MOFs), quantum dots (QDs), and metal-organic framework quantum dots composites (MOFs@QDs) as efficient compounds for the sensing of ecological pollutants, contaminants, and toxicants such as endocrine-disrupting chemicals (EDCs). It also summarizes the compounds or materials used in the detection of bisphenol A (BPA) and the sensing ability of MOFs, QDs, and MOFs@QDs composites for EDCs and BPA.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Zintle Fudo, Peter A. Ajibade, Ayodele T. Odularu
Summary: In this study, five heteroleptic ruthenium(II) polypyridyl complexes were successfully synthesized and characterized. The results showed that these complexes have potential applications in dye-sensitized solar cells due to their high photophysical properties and enhanced dye-sensitizing abilities.
INTERNATIONAL JOURNAL OF PHOTOENERGY
(2022)
Article
Multidisciplinary Sciences
Qing Yang, Kayode Olaifa, Fartisincha P. Andrew, Peter A. Ajibade, Obinna M. Ajunwa, Enrico Marsili
Summary: Dithiocarbamate-zinc metal complex is effective in inhibiting the biofilm of Acinetobacter baumannii by degrading the cell membrane and reducing biofilm formation.
SCIENTIFIC REPORTS
(2022)
Article
Materials Science, Multidisciplinary
Peter A. Ajibade, Athandwe M. Paca, Moganavelli Singh
Summary: We investigated the influence of thermolysis time on the morphological, optical, and anticancer properties of palladium sulfide (PdS) nanoparticles. Our results showed that the palladium sulfide nanoparticles maintained a tetragonal crystalline phase regardless of the thermolysis time. The nanoparticles exhibited spherical shapes with particle sizes ranging from 3.00 to 5.10 nm, and the optical band gaps decreased with increasing thermolysis time. Furthermore, the palladium sulfide nanoparticles showed potential anticancer activity against HeLa cells.
Article
Chemistry, Inorganic & Nuclear
Athandwe M. Paca, Moganavelli Singh, Peter A. Ajibade
Summary: The synthesis, spectroscopic characterization, and in vitro cytotoxic evaluation of five ruthenium(III) dithiocarbamate complexes were reported. The complexes showed moderate cytotoxic activity against human embryonic kidney (HEK293) and cervical cancer (HeLa) cells, with one complex exhibiting the highest activity in both cell lines.
JOURNAL OF COORDINATION CHEMISTRY
(2022)
Article
Chemistry, Physical
Peter A. Ajibade, Amos A. Fatokun, Athandwe M. Paca
Summary: In this study, a new organoruthenium(II) complex was synthesized and characterized. The complex exhibits a centrosymmetric binuclear structure and shows potent cytotoxicity against cervical and lung cancer cell lines. The compound outperformed cisplatin in terms of cytotoxic potency, highlighting its potential as an anti-cancer agent.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Athandwe M. Paca, Saheed O. Benson, Amos A. Fatokun, Peter A. Ajibade
Summary: Four organoruthenium(II) arene dithiocarbamate complexes were synthesized and characterized. The complexes showed promising cytotoxic effects against human cervical cancer and human lung fibroblast cell lines. Two compounds, C1 and C3, exhibited potent cytotoxicity and demonstrated potential as anticancer agents.
JOURNAL OF SULFUR CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Thandi B. Mbuyazi, Peter A. Ajibade
Summary: Octylamine-capped iron oxide nanoparticles (Fe3O4-OTA), 1-dodecanethiol-capped iron oxide nanoparticles (Fe3O4-DDT), and tri-n-octylphosphine-capped iron oxide nanoparticles (Fe3O4-TOP) were prepared by co-precipitation method. The iron oxide nanoparticles exhibited inverse spinel crystalline phases and mean particle sizes of 2.1 nm, 5.0 nm, and 4.4 nm for Fe3O4-OTA, Fe3O4-DDT, and Fe3O4-TOP, respectively. The energy bandgap of the iron oxide nanoparticles ranged from 2.25 eV to 2.76 eV. Fe3O4-TOP nanoparticles showed the highest efficiency in photocatalytic degradation of methylene blue and methyl orange, and scavenger studies revealed the involvement of electrons (e(-)) and hydroxy radicals (& BULL;OH) in the degradation reaction. The pH of the dye solution also affected the photocatalytic degradation, with pH 10 optimal for methylene blue and pH 2 optimal for methyl orange using the iron oxide photocatalyst. The iron oxide photocatalysts showed recyclability without loss of photocatalytic activity.
Article
Chemistry, Multidisciplinary
Peter A. Ajibade, Thandi B. Mbuyazi, Athandwe M. Paca
Summary: The preparation and crystal structures of bis(diallydithiocarbamato)zinc(II) and silver(I) complexes were reported. These compounds were used as single-source precursors to prepare zinc sulfide and silver sulfide nanophotocatalysts. The resulting nanoparticles exhibited excellent performance in terms of light absorption and the degradation of bromothymol blue and bromophenol blue.
Article
Environmental Sciences
Peter A. Ajibade, Ebenezer C. Nnadozie
Summary: Emerging pollutants are uncontrolled pollutants with negative potentials in the environment. This study investigated the sorption of ketoprofen and benzophenone, representative EPs, from aqueous solutions using manganese ferrite biochar as an adsorbent. The results showed that the adsorbent had a high adsorption capacity and good recyclability, making it an effective method for the removal of emerging contaminants.
ENVIRONMENTAL CHEMISTRY AND ECOTOXICOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Abimbola E. Oluwalana, Peter A. Ajibade
Summary: Tin sulfide nanoparticles were prepared using different tin(ii) dithiocarbamate complexes as precursors. The nanoparticles exhibited orthorhombic crystalline structure, small average particle size, and narrow energy bandgap. They showed efficient photocatalytic performance in the degradation of rhodamine B and phenol, and could be repeatedly used without loss of their photodegradation ability.
NANOTECHNOLOGY REVIEWS
(2022)
Review
Chemistry, Multidisciplinary
Lijo P. Mona, Sandile P. Songca, Peter A. Ajibade
Summary: This review focuses on the synthesis and encapsulation of magnetic iron oxide nanorods and their applications in magnetic hyperthermia and photothermal therapy for cancer cells. The results show that monodisperse magnetic oxide nanorods are more effective in cell death compared to polyhedral-shaped nanoparticles.
NANOTECHNOLOGY REVIEWS
(2022)
