Apaf1 inhibition promotes cell recovery from apoptosis

Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death

(2014) M. Sancho et al.   NEUROSCIENCE

Altered Mitochondria Morphology and Cell Metabolism in Apaf1-Deficient Cells

(2014) Mónica Sancho et al.   PLoS One

Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity

(2014) Mar Orzáez et al.   PLoS One

BH3-Mimetics- and Cisplatin-Induced Cell Death Proceeds through Different Pathways Depending on the Availability of Death-Related Cellular Components

(2013) Vicente Andreu-Fernández et al.   PLoS One

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

(2010) Marcello D'Amelio et al.   NATURE NEUROSCIENCE

A chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint

(2009) Laura Mondragón et al.   APOPTOSIS

Neuroprotective strategies targeting apoptotic and necrotic cell death for stroke

(2009) Junying Yuan   APOPTOSIS

Mitochondrial cell death effectors

(2009) Dirk Brenner et al.   CURRENT OPINION IN CELL BIOLOGY

A Nanoconjugate Apaf-1 Inhibitor Protects Mesothelial Cells from Cytokine-Induced Injury

(2009) Beatriz Santamaría et al.   PLoS One

Neuroprotection Against Hypoxic-Ischemic Brain Injury by Inhibiting the Apoptotic Protease Activating Factor-1 Pathway

(2009) Yanqin Gao et al.   STROKE

Reversibility of apoptosis in cancer cells

(2008) H L Tang et al.   BRITISH JOURNAL OF CANCER

Modulation of Cellular Apoptosis with Apoptotic Protease-Activating Factor 1 (Apaf-1) Inhibitors

(2008) L. Mondragón et al.   JOURNAL OF MEDICINAL CHEMISTRY

Apoptosome-deficient Cells Lose Cytochrome c through Proteasomal Degradation but Survive by Autophagy-dependent Glycolysis

(2008) Elisabetta Ferraro et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

(2008) John G. Albeck et al.   MOLECULAR CELL