Article
Multidisciplinary Sciences
Mercy A. Opiyo, Halfan S. Ngowo, Salum A. Mapua, Monica Mpingwa, Nuru Nchimbi, Nancy S. Matowo, Silas Majambere, Fredros O. Okumu
Summary: The study showed that adding sub-lethal doses of PPF to larval habitats of pyrethroid-resistant malaria vectors led to significantly reduced mortality rates of emergent adult mosquitoes when exposed to pyrethroids, but no impact on carbamates or organochlorides. Additionally, mortality rates were reduced for adult mosquitoes exposed to Olyset(R) nets after aquatic exposure to PPF.
Article
Parasitology
Cyntia-Muriel Y. Clegban, Soromane Camara, A. Alphonsine Koffi, Ludovic P. Ahoua Alou, Jean-Paul Kabran Kouame, A. Fernand Koffi, Philippe K. Kouassi, Nicolas Moiroux, Cedric Pennetier
Summary: Long-lasting insecticidal nets (LLINs) have been effective in reducing global malaria burden since 2000. In this study, two new brands of deltamethrin-impregnated nets were evaluated against wild pyrethroid-resistant mosquitoes, showing that they met WHO criteria and are suitable for further testing at the community level. With the increasing pyrethroid resistance, integrated vector management using a variety of control tools is needed for effective malaria control.
PARASITES & VECTORS
(2021)
Article
Multidisciplinary Sciences
Koffi Mensah Ahadji-Dabla, Joseph Chabi, Yawo Georges Apetogbo, Edoh Kof, Melinda Patricia Hadi, Guillaume Koffivi Ketoh
Summary: According to WHO recommendations, it is important to investigate the insecticide resistance profile of the malaria vector before deploying the next generation of LLINs. A study conducted in the cotton-growing area of Kolokope, Togo, found high resistance of Anopheles gambiae s.l. mosquitoes to pyrethroids and DDT, possibly due to excessive use of insecticides in agriculture. These findings can be used to assess the effectiveness of the next generation of LLINs.
Article
Infectious Diseases
Aristide S. Hien, Dieudonne D. Soma, Samina Maiga, Dramane Coulibaly, Abdoulaye Diabate, Allison Belemvire, Mame B. Diouf, Djenam Jacob, Adama Kone, Ellen Dotson, Taiwo S. Awolola, Richard M. Oxborough, Roch K. Dabire
Summary: High intensity pyrethroid resistance in An. gambiae s.l. is widespread in Burkina Faso, prompting the need for alternative insecticide-treated nets. Bioassays showed that susceptibility to chlorfenapyr was confirmed in most sites, while resistance to pyrethroids remains a challenge despite some partial restoration of susceptibility with PBO pre-exposure.
Review
Entomology
William C. Black, Trey K. Snell, Karla Saavedra-Rodriguez, Rebekah C. Kading, Corey L. Campbell
Summary: The use of insecticides is important for controlling biting insects and reducing the spread of insect-borne diseases. Mosquitoes have developed resistance to insecticides, particularly through mechanisms such as metabolism. Pyrethroids, synthetic versions of plant-derived compounds, are commonly used insecticides but mosquito populations with pyrethroid-resistant genetic markers have increased rapidly.
Article
Entomology
Guofa Zhou, Yiji Li, Brook Jeang, Xiaoming Wang, Robert F. Cummings, Daibin Zhong, Guiyun Yan
Summary: This study examined the insecticide resistance mechanisms of mosquitoes to PBO-synergized pyrethroid using Culex quinquefasciatus as a model. The results showed that wild strain mosquitoes were resistant to all tested insecticides, including PBO-synergized pyrethroids. Pre-exposure to PBO reduced the lethal concentration of deltamethrin. The study suggests that PBO alone may not be enough to control highly pyrethroid-resistant mosquitoes.
JOURNAL OF MEDICAL ENTOMOLOGY
(2022)
Article
Parasitology
Jackline L. Martin, Franklin W. Mosha, Eliud Lukole, Mark Rowland, Jim Todd, Jacques D. Charlwood, Jacklin F. Mosha, Natacha Protopopoff
Summary: The study evaluated the personal protection provided by PBO-Py LLIN (Olyset Plus) compared to standard LLIN (Olyset net) against pyrethroid-resistant Anopheles mosquitoes in North-West Tanzania after 20 months of use. The results showed that PBO-Py LLINs offered improved protection, demonstrating higher bioassay mortality and absence of resistant mosquitoes collected from inside the nets, regardless of their physical integrity.
PARASITES & VECTORS
(2021)
Article
Microbiology
Yi-ting Wang, Rui-xin Shen, Dan Xing, Chen-pei Zhao, He-ting Gao, Jia-hong Wu, Ning Zhang, Heng-duan Zhang, Yan Chen, Tong-yan Zhao, Chun-xiao Li
Summary: The study found differences in midgut microbiota among different strains of Culex pipiens quinquefasciatus, with specific microbial species being more abundant in resistant strains. Principal component analysis showed significant differences in metabolic functions between susceptible and resistant strains.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Genetics & Heredity
Yvan Fotso-Toguem, Billy Tene-Fossog, Leon M. J. Mugenzi, Murielle J. Wondji, Flobert Njiokou, Hilary Ranson, Charles S. Wondji
Summary: The polymorphisms of CYP6M2 and CYP6P4 were analyzed to detect potential resistance markers in Anopheles coluzzii and Anopheles gambiae. The study found significant overexpression of CYP6M2 and CYP6P4 in resistant mosquitos, and a lower diversity in the upstream region of CYP6P4 potentially associated with resistance.
Article
Entomology
El Hadji Malick Ngom, Chiara Virgillito, Mattia Manica, Roberto Rosa, Verena Pichler, Noemi Sarleti, Isseu Kasse, Mawlouth Diallo, Alessandra della Torre, Ibrahima Dia, Beniamino Caputo
Summary: Mosquito-borne diseases are significant public health issues in Africa, requiring updated information on mosquito species and monitoring methods. A study in Senegal revealed changes in malaria and lymphatic filariasis vector species populations, emphasizing the importance of using different traps for accurate mosquito monitoring and interpretation of results.
Article
Multidisciplinary Sciences
Marius Gonse Zoh, Jean-Marc Bonneville, Jordan Tutagata, Frederic Laporte, Behi K. Fodjo, Chouaibou S. Mouhamadou, Christabelle Gba Sadia, Justin McBeath, Frederic Schmitt, Sebastian Horstmann, Stephane Reynaud, Jean-Philippe David
Summary: The study compared the impact of a combination of neonicotinoids and pyrethroids on mosquito insecticide resistance, finding that this combination can effectively prevent the selection of resistance to different insecticides. Through 33 generations of controlled selection experiments, the research investigated the dynamics and molecular mechanisms of resistance in An. gambiae to this combination.
SCIENTIFIC REPORTS
(2021)
Article
Entomology
Edmund J. Norris, Jeffrey R. Bloomquist
Summary: With the increasing concern of insecticide-resistant mosquito populations, new vector control technologies are needed. Screening plant essential oils alone or in combination with natural pyrethrins showed that many oils synergized the toxicity of natural pyrethrins, either additively or synergistically. The study identified select plant essential oils that may offer important avenues for the development of future insecticide synergists.
Article
Infectious Diseases
Thomas Syme, Judicael Nounagnon, Boris N'dombidje, Martial Gbegbo, Abel Agbevo, Juniace Ahoga, Corine Ngufor
Summary: The study found that the performance of pyrethroid-CFP nets is reduced when combined with pyrethroid-PBO ITNs compared to when used alone. However, the efficacy is higher with net combinations that include pyrethroid-CFP nets. Therefore, prioritizing the distribution of pyrethroid-CFP nets over other types would maximize vector control impact in similar contexts.
Article
Biology
Ibrahim Kura Shehu, Hamdan Bn Ahmad, Israel Kayode Olayemi, Danjuma Solomon, Abu Hassan Ahmad, Hasber Salim
Summary: The resistance ability of mosquito vectors to insecticides in major diseases in Nigeria is a growing concern for control strategies. This study assessed the susceptibility of Anopheles gambiae and Culex quinquefasciatus mosquitoes to permethrin, propoxur, and malathion in Niger State, Nigeria. The mosquitoes showed potential resistance to permethrin, while most of them were susceptible to malathion.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2023)
Article
Parasitology
Rui-xin Shen, Yi-ting Wang, Jia-hong Wu, Ning Zhang, Heng-duan Zhang, Dan Xing, Yan Chen, Chun-xiao Li, Tong-yan Zhao
Summary: This study reveals for the first time the correlation between the expression of a gene coding for odorant-binding proteins (OBPs) and insecticide resistance in mosquitoes, providing a new target gene for resistance surveillance.
PARASITES & VECTORS
(2022)
