Interferon-γ Inhibits Ebola Virus Infection

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

(2015) Si Ming Man et al.   NATURE IMMUNOLOGY

Immune Evasion in Ebolavirus Infections

(2015) Jonathan Audet et al.   VIRAL IMMUNOLOGY

STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control

(2015) Karoly Toth et al.   PLoS Pathogens

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

A MicroRNA Processing Defect in Smokers' Macrophages Is Linked to SUMOylation of the Endonuclease DICER

(2014) Thomas J. Gross et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Interferon Gamma by a Recombinant Rabies Virus Strongly Attenuates the Pathogenicity of the Virus via Induction of Type I Interferon

(2014) Darryll A. Barkhouse et al.   JOURNAL OF VIROLOGY

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

(2014) S. K. Gire et al.   SCIENCE

Comprehensive Functional Analysis of N-Linked Glycans on Ebola Virus GP1

(2014) N. J. Lennemann et al.   mBio

Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein

(2014) J Galindo-Moreno et al.   Cell Death & Disease

Interferon-stimulated genes: roles in viral pathogenesis

(2014) John W Schoggins   Current Opinion in Virology

Effects of vitamin D supplementation on alveolar macrophage gene expression: preliminary results of a randomized, controlled trial

(2014) Alicia K Gerke et al.   MULTIDISCIPLINARY RESPIRATORY MEDICINE

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

(2013) HyeonJoo Cheon et al.   EMBO JOURNAL

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

(2013) O. Martinez et al.   JOURNAL OF VIROLOGY

Role of the Phosphatidylserine Receptor TIM-1 in Enveloped-Virus Entry

(2013) S. Moller-Tank et al.   JOURNAL OF VIROLOGY

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

(2013) John W. Schoggins et al.   NATURE

Understanding and altering cell tropism of vesicular stomatitis virus

(2013) Eric Hastie et al.   VIRUS RESEARCH

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

(2013) Reed S. Shabman et al.   PLoS Pathogens

Animal models for Ebola and Marburg virus infections

(2013) Eri Nakayama et al.   Frontiers in Microbiology

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

Expression of Complement Components and Regulators by Different Subtypes of Bone Marrow-Derived Macrophages

(2012) Chang Luo et al.   INFLAMMATION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Interferon-β Therapy Prolongs Survival in Rhesus Macaque Models of Ebola and Marburg Hemorrhagic Fever

(2012) Lauren M. Smith et al.   JOURNAL OF INFECTIOUS DISEASES

Essential Cell-Autonomous Role for Interferon (IFN) Regulatory Factor 1 in IFN- -Mediated Inhibition of Norovirus Replication in Macrophages

(2012) N. S. Maloney et al.   JOURNAL OF VIROLOGY

Exosome-mediated delivery of siRNA in vitro and in vivo

(2012) Samir El-Andaloussi et al.   Nature Protocols

Systematic identification of type I and type II interferon-induced antiviral factors

(2012) S.-Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse Models for Filovirus Infections

(2012) Steven B. Bradfute et al.   Viruses-Basel

Ebola and Marburg haemorrhagic fever viruses: major scientific advances, but a relatively minor public health threat for Africa

(2011) E.M. Leroy et al.   CLINICAL MICROBIOLOGY AND INFECTION

Cloning, expression and antiviral activity of IFNγ from the Australian fruit bat, Pteropus alecto

(2011) Vijaya Janardhana et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

(2011) A. S. Kondratowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus

(2011) I-Chueh Huang et al.   PLoS Pathogens

A Novel Role for IFN-Stimulated Gene Factor 3II in IFN-  Signaling and Induction of Antiviral Activity in Human Cells

(2010) A. N. Morrow et al.   JOURNAL OF IMMUNOLOGY

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1

(2010) Daniel J. Gough et al.   PLOS BIOLOGY

Disease modeling for Ebola and Marburg viruses

(2009) D. Bente et al.   Disease Models & Mechanisms

RIG-I activation inhibits ebolavirus replication

(2009) Christina F. Spiropoulou et al.   VIROLOGY

ISG15 Inhibits Nedd4 Ubiquitin E3 Activity and Enhances the Innate Antiviral Response

(2008) Oxana A. Malakhova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin

(2008) N. Jouvenet et al.   JOURNAL OF VIROLOGY

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity

(2008) A. Okumura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA