期刊
TRAFFIC INJURY PREVENTION
卷 11, 期 2, 页码 123-126出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/15389580903518280
关键词
Ethyl glucuronide; Hair analysis; Fitness to drive; Alcohol abuse; Abstinence monitoring
Objective: Ethyl glucuronide (EtG) determinations in the hair of self-reported teetotalers were reviewed and compared with carbohydrate-deficient transferrin (CDT) blood tests (by immunochemistry and high-performance liquid chromatography [HPLC]). Methods: A retrospective study was carried out on 154 people whose fitness to drive had to be assessed because of the suspicion of relevant alcohol problems. Results: EtG was detected in 55 percent of the hair samples and abstinence thus disproved. In two thirds (67%) of these cases, alcohol consumption was even shown to be excessive (EtG values > 30 pg/mg). Of the EtG-positive subjects 54 and 82 percent had CDT values within the reference range by immunochemistry and HPLC, respectively. Thirty-nine percent of the EtG-negative subjects had increased immunochemical CDT values; in contrast, 96 percent had HPLC CDT values within the normal range. Conclusions: EtG analysis in hair is a useful tool for assessing fitness to drive in suspected drinking drivers; compared to CDT values it provides a direct and unequivocal marker for reliable abstinence monitoring over a period of several months, depending on the length of the hair.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据