Role of Flippases, Scramblases and Transfer Proteins in Phosphatidylserine Subcellular Distribution

Sec14-like phosphatidylinositol-transfer proteins and diversification of phosphoinositide signalling outcomes

(2014) Ashutosh Tripathi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mice Deficient in the Putative Phospholipid Flippase ATP11C Exhibit Altered Erythrocyte Shape, Anemia, and Reduced Erythrocyte Life Span

(2014) Mehmet Yabas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics

(2014) William A. Prinz   JOURNAL OF CELL BIOLOGY

Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling

(2014) Nicholas Ariotti et al.   JOURNAL OF CELL BIOLOGY

Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2

(2014) A. L. Vestergaard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

(2014) K. Segawa et al.   SCIENCE

Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation

(2013) R. van Kruchten et al.   BLOOD

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

P4 ATPases: Flippases in Health and Disease

(2013) Vincent van der Mark et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Differential Phospholipid Substrates and Directional Transport by ATP-binding Cassette Proteins ABCA1, ABCA7, and ABCA4 and Disease-causing Mutants

(2013) Faraz Quazi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type IV P-type ATPases Distinguish Mono-versusDiacyl Phosphatidylserine Using a Cytofacial Exit Gate in the Membrane Domain

(2013) Ryan D. Baldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-dependent Phospholipid Scramblase Activity of TMEM16 Protein Family Members

(2013) Jun Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylserine flipping enhances membrane curvature and negative charge required for vesicular transport

(2013) Peng Xu et al.   JOURNAL OF CELL BIOLOGY

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

(2013) Kenji Maeda et al.   NATURE

Two-gate mechanism for phospholipid selection and transport by type IV P-type ATPases

(2013) R. D. Baldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

(2013) J. Suzuki et al.   SCIENCE

Calcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents

(2013) A Kmit et al.   Cell Death & Disease

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

(2013) Mattia Malvezzi et al.   Nature Communications

Phospholipid flippases: Building asymmetric membranes and transport vesicles

(2012) Tessy T. Sebastian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

(2012) Huanghe Yang et al.   CELL

Explaining Calcium-Dependent Gating of Anoctamin-1 Chloride Channels Requires a Revised Topology

(2012) Kuai Yu et al.   CIRCULATION RESEARCH

Missense mutation in the ATPase, aminophospholipid transporter protein ATP8A2 is associated with cerebellar atrophy and quadrupedal locomotion

(2012) Onur Emre Onat et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Phosphatidylserine Stimulation of Drs2p·Cdc50p Lipid Translocase Dephosphorylation Is Controlled by Phosphatidylinositol-4-phosphate

(2012) Aurore Jacquot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amphipathic antenna of an inward rectifier K+ channel responds to changes in the inner membrane leaflet

(2012) M. Iwamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases

(2012) R. D. Baldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer

(2012) Faraz Quazi et al.   Nature Communications

Mutations in a P-Type ATPase Gene Cause Axonal Degeneration

(2012) Xianjun Zhu et al.   PLoS Genetics

P-Type ATPases

(2011) Michael G. Palmgren et al.   Annual Review of Biophysics

A minimal isoform of the TMEM16A protein associated with chloride channel activity

(2011) Loretta Ferrera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane surface charge dictates the structure and function of the epithelial Na+/H+exchanger

(2011) Robert Todd Alexander et al.   EMBO JOURNAL

ATP9B, a P4-ATPase (a Putative Aminophospholipid Translocase), Localizes to thetrans-Golgi Network in a CDC50 Protein-independent Manner

(2011) Hiroyuki Takatsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

(2011) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

(2011) Mehmet Yabas et al.   NATURE IMMUNOLOGY

The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow

(2011) Owen M Siggs et al.   NATURE IMMUNOLOGY

X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C

(2011) O. M. Siggs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive exposure of phosphatidylserine on viable cells

(2011) K. Segawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osh Proteins Regulate Membrane Sterol Organization but Are Not Required for Sterol Movement Between the ER and PM

(2011) Alexander G. Georgiev et al.   TRAFFIC

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Non-vesicular lipid transport by lipid-transfer proteins and beyond

(2010) Sima Lev   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Coordination of Golgi functions by phosphatidylinositol 4-kinases

(2010) Todd R. Graham et al.   TRENDS IN CELL BIOLOGY

Localization, Purification, and Functional Reconstitution of the P4-ATPase Atp8a2, a Phosphatidylserine Flippase in Photoreceptor Disc Membranes

(2009) Jonathan A. Coleman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the sodium–potassium pump at 2.4 Å resolution

(2009) Takehiro Shinoda et al.   NATURE

Emerging roles for lipids in shaping membrane-protein function

(2009) Rob Phillips et al.   NATURE

Reconstitution of phospholipid translocase activity with purified Drs2p, a type-IV P-type ATPase from budding yeast

(2009) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural aspects of ion pumping by Ca2+-ATPase of sarcoplasmic reticulum

(2008) Chikashi Toyoshima   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Distinct Flippases Translocate Glycerophospholipids and Oligosaccharide Diphosphate Dolichols across the Endoplasmic Reticulum†

(2008) Sumana Sanyal et al.   BIOCHEMISTRY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE