Disruption of Clathrin-Mediated Trafficking Causes Centrosome Overduplication and Senescence

DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence

(2016) Olga V. Leontieva et al.   Aging-US

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF

(2013) Łukasz Sadowski et al.   TRAFFIC

Persistent DNA damage caused by low levels of mitomycin C induces irreversible cell senescence

(2012) Elise McKenna et al.   CELL CYCLE

Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG

(2012) Amy B. Foraker et al.   JOURNAL OF CELL BIOLOGY

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane

(2012) L. P. Sousa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth stimulation leads to cellular senescence when the cell cycle is blocked

(2010) Zoya N. Demidenko et al.   CELL CYCLE

Cyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly

(2010) Marvin E. Tanenbaum et al.   CHROMOSOMA

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

(2010) Thomas Kirkegaard et al.   NATURE

The SCFSlimbubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication

(2009) Gregory C. Rogers et al.   JOURNAL OF CELL BIOLOGY

GAK, a regulator of clathrin-mediated membrane traffic, also controls centrosome integrity and chromosome congression

(2009) H. Shimizu et al.   JOURNAL OF CELL SCIENCE

Molecular Dissection of the Centrosome Overduplication Pathway in S-Phase-Arrested Cells

(2009) S. L. Prosser et al.   MOLECULAR AND CELLULAR BIOLOGY

Cdk2 suppresses cellular senescence induced by the c-myc oncogene

(2009) Stefano Campaner et al.   NATURE CELL BIOLOGY

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Signaling from endosomes: Location makes a difference

(2008) Lukasz Sadowski et al.   EXPERIMENTAL CELL RESEARCH

Essential Role of Cyclin-G–associated Kinase (Auxilin-2) in Developing and Mature Mice

(2008) Dong-won Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Roles of cyclins A and E in induction of centrosome amplification in p53-compromised cells

(2008) K Hanashiro et al.   ONCOGENE