Transgenic Fatal Familial Insomnia Mice Indicate Prion Infectivity-Independent Mechanisms of Pathogenesis and Phenotypic Expression of Disease

Cold Exposure and Sleep in the Rat: REM Sleep Homeostasis and Body Size

(2017) Roberto Amici et al.   SLEEP

Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases

(2013) Laura Tapella et al.   BIOCHEMICAL JOURNAL

Spreading proteins in neurodegeneration: where do they take us?

(2013) Giovanna Mallucci   BRAIN

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

PrPST, a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease

(2013) Yael Friedman-Levi et al.   PLoS One

A New Mechanism for Transmissible Prion Diseases

(2012) N. Makarava et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mutant PrP Suppresses Glutamatergic Neurotransmission in Cerebellar Granule Neurons by Impairing Membrane Delivery of VGCC α2δ-1 Subunit

(2012) Assunta Senatore et al.   NEURON

A  neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

(2012) H. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein

(2012) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids

(2012) N. R. Deleault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion protein facilitates uptake of zinc into neuronal cells

(2012) Nicole T. Watt et al.   Nature Communications

De novo generation of prion strains

(2011) David W. Colby et al.   NATURE REVIEWS MICROBIOLOGY

Expression of Mutant or Cytosolic PrP in Transgenic Mice and Cells Is Not Associated with Endoplasmic Reticulum Stress or Proteasome Dysfunction

(2011) Elena Quaglio et al.   PLoS One

Spontaneous generation of anchorless prions in transgenic mice

(2011) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatal Prion Disease in a Mouse Model of Genetic E200K Creutzfeldt-Jakob Disease

(2011) Yael Friedman-Levi et al.   PLoS Pathogens

Variably protease-sensitive prionopathy: A new sporadic disease of the prion protein

(2010) Wen-Quan Zou et al.   ANNALS OF NEUROLOGY

The hydrophobic core region governs mutant prion protein aggregation and intracellular retention

(2010) Emiliano Biasini et al.   BIOCHEMICAL JOURNAL

The genetics of prion diseases

(2010) James A Mastrianni   GENETICS IN MEDICINE

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Conformational diversity in prion protein variants influences intermolecular β-sheet formation

(2009) Seungjoo Lee et al.   EMBO JOURNAL

A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP

(2009) W. Yang et al.   JOURNAL OF NEUROSCIENCE

Mutant Prion Protein Expression Is Associated with an Alteration of the Rab GDP Dissociation Inhibitor α (GDI)/Rab11 Pathway

(2009) Tania Massignan et al.   MOLECULAR & CELLULAR PROTEOMICS

Spontaneous Generation of Prion Infectivity in Fatal Familial Insomnia Knockin Mice

(2009) Walker S. Jackson et al.   NEURON

Fatal familial insomnia: Clinical features and early identification

(2008) Anna Krasnianski et al.   ANNALS OF NEUROLOGY

Sleep-wake behavior and responses to sleep deprivation of mice lacking both interleukin-1β receptor 1 and tumor necrosis factor-α receptor 1

(2008) Francesca Baracchi et al.   BRAIN BEHAVIOR AND IMMUNITY

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

(2008) Houman Khosravani et al.   JOURNAL OF CELL BIOLOGY

Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies

(2008) Emiliano Biasini et al.   JOURNAL OF NEUROCHEMISTRY

Aggregated, Wild-Type Prion Protein Causes Neurological Dysfunction and Synaptic Abnormalities

(2008) R. Chiesa et al.   JOURNAL OF NEUROSCIENCE

Mutant Prion Protein Expression Causes Motor and Memory Deficits and Abnormal Sleep Patterns in a Transgenic Mouse Model

(2008) Sara Dossena et al.   NEURON

De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis

(2008) C. J. Sigurdson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion

(2007) Emiliano Biasini et al.   JOURNAL OF NEUROCHEMISTRY