Article
Optics
Chiaki Ohae, Kenji Hasegawa, Masato Nagano, Soma Tahara, Masayuki Katsuragawa
Summary: In this study, we propose an optimal design for achieving near-full energy conversion while maintaining good TEM00 mode property of fundamental laser radiation in the nanosecond regime. The design is based on standard wavelength conversion using angular phase matching of nonlinear optical crystals arranged in free space, and is applicable to a wide range of wavelengths and laser intensities.
Article
Spectroscopy
Lamyaa M. Almehmadi, Igor K. Lednev
Summary: Stand-off Raman spectroscopy combined with chemometrics has the potential to detect and identify biological stains from a distance for forensic purposes.
JOURNAL OF RAMAN SPECTROSCOPY
(2023)
Article
Optics
Alexey Gorevoy, Olga Polschikova, Alexander Machikhin, Elena Stoykova
Summary: Multi-wavelength digital holographic microscopy (MDHM) is a widely used technique in biological and industrial applications, offering increased height measurement range and the ability to measure concentration using phase delay spectrum. Acousto-optic tunable filters (AOTFs) provide the capability to select multiple bands for multiplexed holograms, but may limit the field of view (FOV) in off-axis holography. This study analyzes the performance of AOTF-based off-axis MDHM setup with diffraction grating or prism to enhance angular multiplexing efficiency.
Proceedings Paper
Engineering, Mechanical
John Macarthur, Jakob Hayden, Matthew Warden, Christopher Carson, David Stothard, Raphael Horvath, Florian Eigenmann, Markus Geiser, Vasili G. Savitski
Summary: A proof-of-concept scanning stand-off dual-comb spectrometer for explosives detection and identification at a 3 m distance is demonstrated. Detection of two types of explosives, RDX and PETN, on various surfaces was carried out using reflection-absorption and backscattering modes. The results show that the device has the features of fast scanning, accurate identification, and low detection limits.
CHEMICAL, BIOLOGICAL, RADIOLOGICAL, NUCLEAR, AND EXPLOSIVES (CBRNE) SENSING XXIII
(2022)
Article
Optics
Xiaohui Guo, Zhenrui Li, Yadong Jiao, Zhipeng Zhao, Chanfei Yao, Zhixu Jia, Kegong Dong, Haoyu Zhang, Honghuan Lin, Weiping Qin, Guanshi Qin
Summary: A shower of mid-infrared Raman solitons at a designed wavelength of 3 µm was successfully generated in a tapered fluorotellurite fiber, providing a new approach for optical soliton generation in fibers.
Article
Computer Science, Information Systems
Elena A. Anashkina, Alexey Andrianov
Summary: This study investigates the generation of optical frequency combs in a silica microsphere, covering multiple telecommunication bands with a 270-nm comb. Different pump wavelengths and dispersion regions have varying effects on the generation of optical frequency combs, with the mechanisms of individual peaks verified through numerical simulations.
Article
Engineering, Electrical & Electronic
Roopa Prakash, Vishal Choudhury, S. Arun, V. R. Supradeepa
Summary: The addition of transmission fiber before the nonlinear broadening stage overcomes poor spectral flatness and sensitivity issues in low-power continuous-wave pumped supercontinuum sources. The proposed two-stage spectral broadening technique successfully demonstrates a continuous-wave pump wavelength agile all-fiber supercontinuum module with spectra spanning from 1300 nm to 2000 nm.
IEEE PHOTONICS TECHNOLOGY LETTERS
(2021)
Article
Engineering, Biomedical
Vedran Nedelkovski, Orestis G. Andriotis, Karin Wieland, Christoph Gasser, Andreas Steiger-Thirsfeld, Johannes Bernardi, Bernhard Lendl, Michael L. Pretterklieber, Philipp J. Thurner
Summary: Bone tissue has unique mechanical properties due to its complex hierarchical structure. Testing of bone structures at the microscale using techniques like FIB and AFM has shown the importance of water for bone mechanics and the potential increase in bone fragility with age, linked to decreased energy dissipation.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Instruments & Instrumentation
Christopher K. Akhgar, Vanessa Nuernberger, Marlene Nadvornik, Victoria Ramos-Garcia, Isabel Ten-Domenech, Julia Kuligowski, Andreas Schwaighofer, Erwin Rosenberg, Bernhard Lendl
Summary: This study presents a novel method for determining the fatty acid composition of human milk using mid-infrared spectroscopy. By analyzing the absorbance spectra of pure milk fat recorded via attenuated total reflection Fourier transform infrared spectroscopy and combining the results with gas chromatography-mass spectrometry measurements, multivariate regression equations were established to predict fatty acid concentrations. The method achieved good predictions for various important fatty acid parameters, demonstrating its high accuracy.
APPLIED SPECTROSCOPY
(2022)
Article
Instruments & Instrumentation
Dominik Wacht, Mauro David, Borislav Hinkov, Hermann Detz, Andreas Schwaighofer, Bettina Baumgartner, Bernhard Lendl
Summary: The study presents the development of a mesoporous zirconia coating on ATR crystals to address the chemical stability issues of mesoporous silica in alkaline aqueous solutions, enabling in situ monitoring of organic pollutants. The coating exhibits strong chemical stability and high enrichment performance, with low detection limits for benzonitrile and valeronitrile.
APPLIED SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Alicja Dabrowska, Mauro David, Stephan Freitag, Aaron Maxwell Andrews, Gottfried Strasser, Borislav Hinkov, Andreas Schwaighofer, Bernhard Lendl
Summary: Mid-infrared chemical sensors based on quantum cascade technology were developed for broadband detection of aqueous samples targeting bovine milk proteins. The setup combined a tunable quantum cascade laser with a spectrally tailored in-house fabricated quantum cascade detector, showing similar performance to a high-end FTIR spectrometer. The study highlights the potential of quantum cascade detectors in next-generation MIR liquid-phase chemical sensors with low noise and high dynamic range.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Christopher K. Akhgar, Julian Ebner, Oliver Spadiut, Andreas Schwaighofer, Bernhard Lendl
Summary: In this study, an external cavity-quantum cascade laser-based mid-infrared spectrometer was used for in-line monitoring of proteins from preparative ion-exchange chromatography. Advanced background compensation strategies were implemented to obtain high-quality protein spectra, showing the potential to replace laborious off-line methods for protein monitoring.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Daniel R. Hermann, Georg Ramer, Markus Kitzler-Zeiler, Bernhard Lendl
Summary: Vibrational circular dichroism (VCD) is a powerful technique for determining the absolute configuration of molecules. This study presents an improved setup for VCD measurement using an external cavity quantum cascade laser as a light source, which allows for faster measurements with competitive noise levels. The setup offers higher temporal resolution and shorter measurement times compared to traditional methods.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Shilpa Vijayakumar, Jeremy Rowlette, Andreas Schwaighofer, Bernhard Lendl
Summary: The stability of high-concentration protein formulations is a significant challenge in biopharmaceutical development. This study used laser-based mid-infrared spectroscopy to investigate the effect of protein concentration and the presence of sugars on the thermal denaturation of bovine serum albumin (BSA). The results showed that high BSA concentrations led to lower denaturation temperatures, while different sugars had both stabilizing and destabilizing effects.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
A. Catarina V. D. dos Santos, Nikolaus Hondl, Victoria Ramos-Garcia, Julia Kuligowski, Bernhard Lendl, Georg Ramer
Summary: Researchers have found that the application of conventional IR microscopy in the life sciences is limited due to the restrictions on spatial resolution. The use of AFM-IR technology allows for chemical analysis of biomolecules at the nanoscale, which can contribute to the investigation of nano and microscale biological processes.
ACS MEASUREMENT SCIENCE AU
(2023)
Article
Instruments & Instrumentation
Daniel-Ralph Hermann, Georg Ramer, Lisa Riedlsperger, Bernhard Lendl
Summary: Recently, high-throughput quantum cascade laser-based vibrational circular dichroism (QCL-VCD) technology has significantly reduced the measurement time for high-quality vibrational circular dichroism spectra. This study evaluated the feasibility of using QCL-VCD for chiral monitoring in a circulating system. The results showed that QCL-VCD demonstrated good sensitivity to both molar and enantiomeric excess (EE), making it suitable for high-resolution chiral monitoring in chemical processes.
APPLIED SPECTROSCOPY
(2023)
Article
Physics, Applied
E. V. Bergmann, G. V. B. Lukasievicz, B. Lendl, A. R. Sampaio, V. S. Zanuto, M. L. Baesso, L. C. Malacarne, N. G. C. Astrath
Summary: An all-optical photoinduced lensing method for exciting and monitoring acoustic waves in liquids is introduced in this article. The method utilizes a laser pulse to generate a localized temperature gradient, which launches pressure waves in the liquid at a nanosecond timescale. The refractive index change caused by acoustic and thermal effects can be sensed by a probe laser beam. The physical properties of the liquids can be quantitatively described based on the theoretical description of the intensity signal.
JOURNAL OF APPLIED PHYSICS
(2023)
Article
Plant Sciences
Jessica C. Huss, Sebastian J. Antreich, Martin Felhofer, Konrad Mayer, Michaela Eder, Ana Catarina Vieira Dias dos Santos, Georg Ramer, Bernhard Lendl, Notburga Gierlinger
Summary: The water caltrop develops unique woody fruits with unusually large seeds among aquatic plants. Hydrolyzable tannins flood the endocarp tissue during fruit development and lignin is integrated into the cell walls during maturation. The presence of ester linkages in the mature tissue suggests that gallotannins and their derivatives are cross-linked to other wall components, leading to unique cell-wall properties.
Article
Chemistry, Analytical
Ivan Rienda, Erika Moro, Alvaro Perez-Rubio, Ramon Trullenque-Juan, David Perez-Guaita, Bernhard Lendl, Julia Kuligowski, Jose V. Castell, Judith Perez-Rojas, Eugenia Pareja, Guillermo Quintas
Summary: Near-infrared and attenuated total reflectance-Fourier transform mid-infrared spectroscopy can be used for real-time quantitative assessment of liver steatosis, playing a crucial role in the success of liver transplantation surgery.
Article
Chemistry, Analytical
Ivan Rienda, Isabel Ten-Domenech, Erika Moro, Marta Moreno-Torres, Judith Perez-Rojas, Eugenia Pareja, Alvaro Perez-Rubio, Ramon Trullenque, Ramiro Jover, Bernhard Lendl, David Perez-Guaita, Julia Kuligowski, Jose V. Castell, Guillermo Quintas
Summary: The assessment of liver steatosis is crucial in hepatology and liver transplantation surgery. Current methods for evaluating steatosis are time-consuming, subjective, and lack reproducibility. Recent research has shown that infrared spectroscopy could be used for real-time quantification of steatosis during abdominal surgery. This study developed and validated digital image analysis methods that provide accurate and reproducible reference values for steatosis quantification, enhancing the performance of infrared spectroscopic models. A PLS model in the 1810-1052 cm(-1) region using first derivative ATR-FTIR spectra provided RMSECV = 0.99%.
Article
Biochemical Research Methods
Florian Pilat, Benedikt Schwarz, Bettina Baumgartner, Daniela Ristanic, Hermann Detz, Aaron M. M. Andrews, Bernhard Lendl, Gottfried Strasser, Borislav Hinkov
Summary: Quality control of liquids plays a crucial role in analytical chemistry, and the gold standard for measuring residual water in organic solvents and pharmaceutical applications is Karl Fischer titration. A high-performance lab-on-a-chip sensor based on mid-IR spectroscopy is proposed for real-time analysis of residual water concentration in isopropyl alcohol. Two experiments demonstrate its ability to detect water content with high sensitivity and rapid response time. The sensor achieves a limit of detection between 120 ppm and 150 ppm for the flow cell configuration and 1.5 x 10(-2)%(vol) to 19%(vol) in the in situ configuration.
Article
Chemistry, Analytical
A. Catarina V. D. dos Santos, Davide Tranchida, Bernhard Lendl, Georg Ramer
Summary: The routine analysis of polymer blends at the nanoscale usually requires electron microscopy techniques. The tapping mode AFM-IR, a recent technique that combines AFM's resolution with chemical information, is useful for analyzing highly heterogeneous samples.
Review
Chemistry, Analytical
Claudia Campanale, Silvia Galafassi, Francesca Di Pippo, Iulian Pojar, Carmine Massarelli, Vito Felice Uricchio
Summary: Biodegradable plastic mulches (BDMs) have the potential to be an eco-friendly alternative to conventional plastic mulches in agriculture. However, their long-term impacts on soil ecosystems are still uncertain, and further research is needed. Incorporating BDMs into the soil may stimulate microbial activity, but there is also a risk of incomplete degradation and release of residual microplastics and additives.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Xuechi Yin, Sijie Liu, Deepak Kukkar, Jianlong Wang, Daohong Zhang, Ki-Hyun Kim
Summary: The lateral flow immunoassay strip is a classic and dominant tool in point-of-care detection, known for its portability and simplicity. However, current colored nanomaterials used as signal labels in LFIA have limited sensing potential, leading to the recognition of composite nanoparticles as alternatives to enhance sensitivity, signal readout diversity, anti-matrix interference, and cost-effectiveness.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Yaxin Cao, Longyi Shao, Timothy P. Jones, Wenjing Deng, M. Santosh, Pengju Liu, Cheng-Xue Yang, Yaowei Li, Daizhou Zhang, Kelly Berube
Summary: The toxicity of fibrous particles in ambient air can be higher than other types of particles. Microfibers can be organic or inorganic and their presence in the atmosphere as a result of human activity raises concerns for environmental and public health. Accurate collection, identification, and understanding of the health hazards associated with these fibers are crucial for mitigation strategies and protection of public health.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Chenchen Xie, Chen Meng, Huilin Liu, Baoguo Sun
Summary: The development of food hazard factor (FHF) detection has been moving towards on-site inspection and mobile law enforcement, calling for simple, fast, and affordable analysis technology to ensure food safety and quality. This review comprehensively summarizes the progress in research on smartphone-assisted MIP optosensors, focusing on the key issues of accuracy and sensitivity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Guillem Peris-Pastor, Cristian Azorin, Jose Grau, Juan L. Benede, Alberto Chisvert
Summary: Green Analytical Chemistry plays an important role in every stage of method development, including sample preparation. Extraction techniques have evolved from conventional ones to a variety of miniaturized techniques in order to enhance analytical performance and ensure safety for operators and the environment. Green metric tools are used to evaluate the impact and sustainability of methods, with AGREEprep selected as the most suitable tool for evaluating published methods in various applications. The miniaturization of sample preparation strategies has led to the use of less and safer solvents, reduced waste generation and energy consumption, and improved portability and throughput.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Helena Hruskova, Roman Reminek, Frantisek Foret
Summary: This review article summarizes the progress and recent studies in offline electromigration preparative techniques between 2018 and 2023. It covers various techniques including electrophoresis, free-flow electrophoresis, isoelectric focusing, and isotachophoresis, providing theoretical aspects, trends, and solutions to existing limitations in each technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Mayank Garg, Nicole Pamme
Summary: This review focuses on the removal strategies of templates from molecularly imprinted polymers (MIPs) used in diagnostic biosensors. Chemical-based and electrochemical-based template extraction approaches are summarized and evaluated, providing guidance for researchers in the fields of analytical chemistry, diagnostics, and materials science for the design of MIP-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Ivneet Banga, Anirban Paul, Nathan Kodjo Mintah Churcher, Ruchita Mahesh Kumar, Sriram Muthukumar, Shalini Prasad
Summary: Breathomics is an emerging field that focuses on analyzing exhaled breath to diagnose and monitor respiratory diseases. Electrochemical sensors, with their high sensitivity, selectivity, and low cost, play a significant role in breathomics and can be integrated into portable devices for point-of-care diagnosis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Fabjola Bilo, Paola Cirelli, Laura Borgese
Summary: This review explores the application of X-ray fluorescence (XRF) spectrometry for elemental analysis of particulate matter (PM) in air quality monitoring. It discusses the fundamentals of XRF, experimental configurations, PM sampling devices and substrate, sample preparation strategies, qualitative and quantitative analysis, as well as the challenges faced by XRF in becoming a reliable analytical technique for PM analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hakim Faraji
Summary: The dispersive liquid-liquid microextraction (DLLME) technique is widely popular in analytical chemistry due to its high efficiency, cost-effectiveness, and simplicity. Recent advancements have addressed the limitations of DLLME, incorporating greener solvents, innovative dispersion strategies, and simplified procedures. These changes have made DLLME a more sustainable and efficient technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair, Reda M. Abdelhameed, Marcello Locatelli, Fotouh R. Mansour
Summary: Carbon nanomaterials (CNMs) have excellent capabilities in terms of adsorption, enhanced oxidation, and photocatalysis, attracting widespread attention in different fields. Metal-organic frameworks (MOFs) have been widely used due to their regular network structure, porous nature, and large specific surface area. However, the instability of MOFs in aqueous solutions limits their applications in chemical sensing. Recent studies have focused on increasing the stability of MOFs in water-based matrices through chemical modifications using CNMs.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Alexandra Pape, Oliver J. Schmitz
Summary: Low temperature plasmas based on dielectric barrier discharges have emerged as a recent development in ion source research. These ion sources are applicable to heat-sensitive analytes and can ionize a wide range of compounds. Despite intensive research on important parameters such as configuration, shape, size, and materials in the past two decades, the actual ionization mechanism for all plasma gases has not been fully elucidated. This review provides an overview of atmospheric pressure ion sources, with a focus on plasma and dielectric barrier discharge based ion sources, summarizing the reactions occurring in the plasma and discussing the applications developed by different research groups.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hai Xiong, Fengli Li, Linyu Zeng, Qiyu Lei
Summary: This review provides an overview of the emerging trends in the use of functional COF nanomaterials as biosensors for DNA/RNA detection. It summarizes the construction of DNA/RNA hybridized COF nanoprobes and their potential applications in bioanalyte detection, biosensing, biomarker imaging, and clinical biomedicine.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Bing Yan
Summary: This article summarizes the recent progress in logic gate computing and operation based on multiple luminescence response and chemical sensing for lanthanide functionalized MOF hybrid systems. The article first describes multi-color luminescence and the subsequent multiple luminescence response. The basic concept of logic gate operation and the advantages of lanthanide-based hybrid materials are then introduced. Reports on logic gate operation using pure lanthanide MOFs are provided, followed by a detailed summary of logic gate operations using lanthanide functionalized MOF hybrid materials. Additionally, the article discusses the practical luminescent detection of analytes by correlating the luminescence responsive signals and the concentration of different analytes. Finally, the article concludes with a prospect for this topic.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Brij Mohan, Gurjaspreet Singh, Rakesh Kumar Gupta, Pawan Kumar Sharma, Alexander A. Solovev, Armando J. L. Pombeiro, Peng Ren
Summary: Porous materials, particularly hydrogen-bonded organic frameworks (HOFs), have gained significant attention due to their versatile applications and unique properties such as well-defined crystalline structure and easy regeneration processes. This article provides a comprehensive overview of HOFs, including synthesis methods, hydrogen bonding motifs, recent advancements, and potential applications, offering valuable guidance for further exploration in this dynamic field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
