Article
Biochemical Research Methods
Christoph Schaefer, Florian Schlottmann, Ansgar T. Kirk, Stefan Zimmermann
Summary: High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) chemically ionize gaseous samples and separate ions under high reduced electric field strengths. Increasing sample gas humidity shifts the mechanism of product ion formation from charge transfer to proton transfer. For HiKE-IMS, increasing sample gas humidity benefits the ionization yield of most analytes.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Chemistry, Multidisciplinary
Karen E. Butler, Yoshihiko Takinami, Adam Rainczuk, Erin S. Baker, Blaine R. Roberts
Summary: Native mass spectrometry combined with IMS-MS technology can be used to study the tertiary and quaternary structure of proteins, validate other structural determination methods, and provide more comprehensive structural information.
FRONTIERS IN CHEMISTRY
(2021)
Review
Chemistry, Analytical
Daniel G. Delafield, Gaoyuan Lu, Cameron J. Kaminsky, Lingjun Li
Summary: Mass spectrometry-based biomolecular analyses have become popular in research settings. Gas phase ion separation techniques provide a fourth dimension of analysis, enabling rapid characterization and high throughput profiling. This review highlights the latest developments and applications of high-end ion-mobility enabled instruments and their advantages for biomolecular research.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Stefan Lukow, James C. Weatherall
Summary: The verification of trace explosives detection systems is often limited to small sample sets, requiring statistical analysis to support the significance of the results. This study presents a method based on probability confidence interval to assess the trials and provides useful measures of the system's performance. Additionally, statistical tests are conducted to examine the propriety of combining statistics for similar tests.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
David S. Roberts, Morgan Mann, Jake A. Melby, Eli J. Larson, Yanlong Zhu, Allan R. Brasier, Song Jin, Ying Ge
Summary: Researchers have successfully elucidated the complete structure of newly discovered O-glycans on the S protein regional-binding domain (SR-BD) of the SARS-CoV-2 virus through a hybrid mass spectrometry approach. This method can provide insights into the interactions between the virus and host cells, laying a foundation for understanding the functional roles of O-glycans in SARS-CoV-2 and other glycoproteins.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Biochemistry & Molecular Biology
Wojciech Fabianowski, Miroslaw Maziejuk, Monika Szyposzynska, Monika Wisnik-Sawka
Summary: The article presents a technique of differential ion mobility spectrometry (DMS) for the detection and identification of volatile organic compounds (VOCs) from various categories. It analyzes the possibility of mixture identification using only the DMS spectrometer and provides several examples. The article also discusses the analysis of different compounds, their mechanisms of fragmentation, influence on effective ion temperature, and high electric field intensity.
Article
Biochemical Research Methods
Kevin Hooijschuur, Xiufen Liu, Anna Grootendorst, Ines Pieterman, Javier Sastre Torano
Summary: The use of mixed ion exchange particles and diatomite allows for high-capacity analysis of low-abundant compounds in CZE-DTIMS-MS, increasing sample injection volumes and flow rates.
Article
Spectroscopy
Robert Teuma-Castelletti, Ahmed Al Hejami, Diane Beauchemin
Summary: This study uses off-the-shelf infrared heaters to heat the sample introduction system on a Varian 820MS instrument, resulting in improved sensitivities and detection limits. The infrared heating increases sensitivities by a factor of 2 to 16 and improves detection limits by a factor of 1.1 to 3.5 for most analytes. It also reduces the formation of doubly charged species. The infrared heating also enhances plasma robustness.
ATOMIC SPECTROSCOPY
(2022)
Article
Chemistry, Physical
Marshall R. Ligare, Kelsey A. Morrison, Michael A. Hewitt, J. Ulises Reveles, Niranjan Govind, Heriberto Hernandez, Erin S. Baker, Brian H. Clowers, Julia Laskin, Grant E. Johnson
Summary: By employing ion mobility spectrometry and density functional theory, the structure of Au-7(PPh3)(7)H-5(2+) was determined, with hydrogen-containing species identified as potential intermediates in the formation of larger phosphine ligated gold clusters.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Applied
Minna Juvonen, Edwin Bakx, Henk Schols, Maija Tenkanen
Summary: This study investigated the potential of using TWIMS and CID-TWIMS-MS/MS to separate cereal-derived isomeric arabinoxylanoligosaccharides (A)XOS. The triand pentasaccharide isomers were distinguishable by the ATDs of the precursor ions, while CID-TWIMS-MS/MS could effectively separate isomeric fragment ions produced from tetra- and pentasaccharide (A)XOS. The base peak mobility spectrum was also introduced as a practical tool for (A)XOS fingerprinting.
Article
Biochemical Research Methods
Yen -Chen Liao, James M. Fulcher, David J. Degnan, Sarah M. Williams, Lisa M. Bramer, Dusan Velickovic, Kevin J. Zemaitis, Marija Velickovic, Ryan L. Sontag, Ronald J. Moore, Ljiljana Pasa-Tolic, Ying Zhu, Mowei Zhou
Summary: Conventional proteomic approaches cannot accurately measure signals from sub-populations of cells, while recent developments in bottom-up proteomics enable spatial mapping of cellular heterogeneity. However, bottom-up proteomics cannot define and quantify intact forms of proteins capturing genetic variations and posttranslational modifications. A spatially resolved top-down proteomics (TDP) platform is described, which allows direct identification and quantitation of proteoforms from tissue sections. This platform consists of a nanodroplet processing system for sample preparation and a laser capture microdissection-based cell isolation system. The improved sample preparation method enhances the coverage of nuclear proteins. The TDP platform has potential for biomarker discovery at the proteoform level from small tissue sections.
MOLECULAR & CELLULAR PROTEOMICS
(2023)
Article
Biochemical Research Methods
Noor A. Aly, James N. Dodds, Yu-Syuan Luo, Fabian A. Grimm, MaKayla Foster, Ivan Rusyn, Erin S. Baker
Summary: Persistent organic pollutants (POPs) pose risks to human health and the environment, requiring effective assessment methods. Chromatography coupled with mass spectrometry (MS) is commonly used, but challenges arise from the diverse range of chemical classes, necessitating multiple time-consuming analyses for different types of POPs. Ion mobility spectrometry coupled with MS (IMS-MS) shows potential as a rapid screening technique for assessing a variety of POP compounds and their metabolites.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Ludwig R. Sinn, Sven H. Giese, Marchel Stuiver, Juri Rappsilber
Summary: Ion-mobility spectrometry has the potential to solve analytically challenging research questions by adding an extra separation dimension to liquid chromatography-mass spectrometry. By using machine learning, the understanding of field asymmetric waveform ion-mobility spectrometry for the analysis of cross-linked peptides has been deepened and ideal compensation voltages correlating with chromatography fraction number have been identified.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Dylan H. Ross, Joon-Yong Lee, Aivett Bilbao, Daniel J. Orton, Josie G. Eder, Meagan C. Burnet, Brooke L. Deatherage Kaiser, Jennifer E. Kyle, Xueyun Zheng
Summary: A Python tool called LipidOz was developed for the automated determination of lipid double bond positions from complex LC-OzID-IMS-MS data, using a combination of traditional automation and deep learning approaches. The development of this tool provides practical application for lipidomics research.
COMMUNICATIONS CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jan Leipert, Philipp T. Kaulich, Max K. Steinbach, Britta Steer, Konrad Winkels, Christine Blurton, Matthias Leippe, Andreas Tholey
Summary: Researchers have developed a sample preparation method based on protein aggregation and acidic elution, allowing for sensitive protein identification analysis of single nematodes on a digital microfluidics device. Compared to in-tube sample preparation, this method increases proteoform identifications by 46%. Label-free quantification also reveals changes in proteoform abundance that cannot be distinguished by bottom-up proteomics. This workflow facilitates proteoform-focused analysis on limited availability samples.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Food Science & Technology
Maria Garcia-Nicolas, Natalia Arroyo-Manzanares, Lourdes Arce, Manuel Hernandez-Cordoba, Pilar Vinas
Review
Chemistry, Analytical
Maria Jose Cardador, Carolina Reyes-Palomo, Cipriano Diaz-Gaona, Lourdes Arce, Vicente Rodriguez-Estevez
Summary: The global emission and accumulation of gases due to livestock farming account for approximately 14.5% of the global warming effect caused by greenhouse gases (GHG), with pig farming contributing 9% of the total. Reliable sampling and analytical techniques are needed to accurately measure the GHG emissions from pig farms, as most current information is based on theoretical calculations. The selection of the best detection method is crucial for climate change policies and evaluating practices to reduce emissions.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Natividad Jurado-Campos, Andres Martin-Gomez, David Saavedra, Lourdes Arce
Summary: The article highlights the potential and importance of headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) in non targeted qualitative analysis, as well as discusses a novel quality control protocol suitable for different users.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Food Science & Technology
Natividad Jurado-Campos, Maria Garcia-Nicolas, Marta Pastor-Belda, Tom Bussmann, Natalia Arroyo-Manzanares, Brigida Jimenez, Pilar Vinas, Lourdes Arce
Summary: This study investigated the potential of using HS-UV-IMS for the untargeted volatile fingerprinting of organic and conventional olives, achieving a success rate of 94.39%. For olive oil samples, HS-GC-IMS and CE-UV techniques were employed for analysis, with CE-UV showing higher classification accuracy (95.76%) and more stability over time.
Article
Chemistry, Analytical
Rafael Freire, Luis Fernandez, Celia Mallafre-Muro, Andres Martin-Gomez, Francisco Madrid-Gambin, Luciana Oliveira, Antonio Pardo, Lourdes Arce, Santiago Marco
Summary: The GC-IMS technology allows for fast, reliable, and inexpensive chemical composition analysis of volatile mixtures, but the data processing can be complex and requires pre-processing. This study presents four different approaches for feature extraction and applies them to a dataset of Iberian ham samples to test the ability to infer chemical information from samples. The choice of feature extraction strategy is a balance between preserving chemical information and the computational effort required to generate data models.
Article
Agriculture, Dairy & Animal Science
Miriam Hernandez-Jimenez, Isabel Revilla, Lourdes Arce, Maria Jose Cardador, Rocio Rios-Reina, Inmaculada Gonzalez-Martin, Ana Maria Vivar-Quintana
Summary: The study demonstrates that both Near Infrared Spectroscopy and Gas Chromatography-Mass Spectrometry techniques are effective in classifying and authenticating Iberian pork raw materials without the need for chemical treatment. The use of these two techniques provides significant advantages for the industry.
Article
Food Science & Technology
Andres Martin-Gomez, Natalia Arroyo-Manzanares, Maria Garcia-Nicolas, Angela Lopez-Lorente, Soledad Cardenas, Ignacio Lopez-Garcia, Pilar Vinas, Manuel Hernandez-Cordoba, Lourdes Arce
Summary: The study used Raman spectroscopy as a rapid screening tool to successfully differentiate dry-cured Iberian ham samples of different feeding regimes and breeds, providing new possibilities for preventing labeling fraud. The method showed high validated classification rates for feeding regime (83.3%) and breed (86.7%), with an interlaboratory study confirming its applicability with a validated rate above 80% for 52 samples.
Review
Veterinary Sciences
Pablo Rodriguez-Hernandez, Vicente Rodriguez-Estevez, Lourdes Arce, Jaime Gomez-Laguna
Summary: VOCs analysis can serve as an effective method for diagnosing diseases, particularly in cases where current diagnostic techniques have low sensitivity, playing an important role in the diagnosis of tuberculosis and paratuberculosis.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Food Science & Technology
Andres Martin-Gomez, M. Pilar Segura-Borrego, Rocio Rios-Reina, M. Jose Cardador, Raquel M. Callejon, M. Lourdes Morales, Vicente Rodriguez-Estevez, Lourdes Arce
Summary: The study evaluated the quality of Iberian ham using advanced instrumental methods like HS-GC-IMS and HS-GC-MS to discriminate defective hams through non-destructive sampling. The results showed that these instrumental methods were effective in discriminating defective hams, and also provided insights into the volatile profile of spoiled Iberian hams, aiding in maintaining the quality of hams in the market.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Applied
M. P. Segura-Borrego, A. Martin-Gomez, R. Rios-Reina, M. J. Cardador, M. L. Morales, L. Arce, R. M. Callejon
Summary: The study demonstrates that using GC-MS or GC-IMS techniques combined with nondestructive sampling methods for identification of dry-cured Iberian ham is feasible. HS-GC-IMS is more sensitive than HS-GC-MS, detecting more compounds and providing accurate qualitative results. Principal component analysis identified potential markers for differentiation.
Article
Microbiology
Pablo Rodriguez-Hernandez, Maria Jose Cardador, Rocio Rios-Reina, Jose Maria Sanchez-Carvajal, Angela Galan-Relano, Francisco Jurado-Martos, Inmaculada Luque, Lourdes Arce, Jaime Gomez-Laguna, Vicente Rodriguez-Estevez
Summary: This study evaluates the potential of gas chromatography coupled to ion mobility spectrometry (GC-IMS) in discriminating cattle infected by Mycobacterium tuberculosis complex (MTC) from non-infected animals. Volatile organic compounds (VOCs) produced from feces were analyzed and chemometrics were used to process the data. The results demonstrate that this approach has a robust performance in identifying the infection and non-infection status with high accuracy and sensitivity.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Pablo Rodriguez-Hernandez, Maria Jose Cardador, Rocio Rios-Reina, Jose Maria Sanchez-Carvajal, Angela Galan-Relano, Francisco Jurado-Martos, Inmaculada Luque, Lourdes Arce, Jaime Gomez-Laguna, Vicente Rodriguez-Estevez
Summary: Bovine tuberculosis is a re-emerging disease that poses risks to the livestock sector and public health. Current diagnostic procedures have drawbacks, and alternative tools are needed. This study evaluates the potential of gas chromatography coupled to ion mobility spectrometry (GC-IMS) in distinguishing naturally infected cattle from non-infected animals.
MICROBIOLOGY SPECTRUM
(2023)
Review
Chemistry, Analytical
Natividad Jurado-Campos, Rocio Rodriguez-Gomez, Natalia Arroyo-Manzanares, Lourdes Arce
Summary: This review explores alternative techniques for classifying olive oils, complementing the current official methods, and provides a detailed description of their advantages and disadvantages. These new techniques can replace or supplement the conventional physicochemical analysis and sensory tasting methods.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
P. Rodriguez-Hernandez, M. J. Cardador, L. Arce, V. Rodriguez-Estevez
Summary: Volatilome analysis is gaining attention for disease diagnosis in animals and humans. Fecal samples are being proposed as a fast, easy, and noninvasive method for disease diagnosis. However, fecal samples are complex and require special consideration and preparation. This review evaluates the analytical methods, advantages, and limitations in studies focused on the diagnosis of animal diseases through fecal volatilome.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Natividad Jurado-Campos, Natalia Arroyo-Manzanares, Pilar Vinas, Lourdes Arce
Review
Chemistry, Analytical
Claudia Campanale, Silvia Galafassi, Francesca Di Pippo, Iulian Pojar, Carmine Massarelli, Vito Felice Uricchio
Summary: Biodegradable plastic mulches (BDMs) have the potential to be an eco-friendly alternative to conventional plastic mulches in agriculture. However, their long-term impacts on soil ecosystems are still uncertain, and further research is needed. Incorporating BDMs into the soil may stimulate microbial activity, but there is also a risk of incomplete degradation and release of residual microplastics and additives.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Xuechi Yin, Sijie Liu, Deepak Kukkar, Jianlong Wang, Daohong Zhang, Ki-Hyun Kim
Summary: The lateral flow immunoassay strip is a classic and dominant tool in point-of-care detection, known for its portability and simplicity. However, current colored nanomaterials used as signal labels in LFIA have limited sensing potential, leading to the recognition of composite nanoparticles as alternatives to enhance sensitivity, signal readout diversity, anti-matrix interference, and cost-effectiveness.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Yaxin Cao, Longyi Shao, Timothy P. Jones, Wenjing Deng, M. Santosh, Pengju Liu, Cheng-Xue Yang, Yaowei Li, Daizhou Zhang, Kelly Berube
Summary: The toxicity of fibrous particles in ambient air can be higher than other types of particles. Microfibers can be organic or inorganic and their presence in the atmosphere as a result of human activity raises concerns for environmental and public health. Accurate collection, identification, and understanding of the health hazards associated with these fibers are crucial for mitigation strategies and protection of public health.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Chenchen Xie, Chen Meng, Huilin Liu, Baoguo Sun
Summary: The development of food hazard factor (FHF) detection has been moving towards on-site inspection and mobile law enforcement, calling for simple, fast, and affordable analysis technology to ensure food safety and quality. This review comprehensively summarizes the progress in research on smartphone-assisted MIP optosensors, focusing on the key issues of accuracy and sensitivity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Guillem Peris-Pastor, Cristian Azorin, Jose Grau, Juan L. Benede, Alberto Chisvert
Summary: Green Analytical Chemistry plays an important role in every stage of method development, including sample preparation. Extraction techniques have evolved from conventional ones to a variety of miniaturized techniques in order to enhance analytical performance and ensure safety for operators and the environment. Green metric tools are used to evaluate the impact and sustainability of methods, with AGREEprep selected as the most suitable tool for evaluating published methods in various applications. The miniaturization of sample preparation strategies has led to the use of less and safer solvents, reduced waste generation and energy consumption, and improved portability and throughput.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Helena Hruskova, Roman Reminek, Frantisek Foret
Summary: This review article summarizes the progress and recent studies in offline electromigration preparative techniques between 2018 and 2023. It covers various techniques including electrophoresis, free-flow electrophoresis, isoelectric focusing, and isotachophoresis, providing theoretical aspects, trends, and solutions to existing limitations in each technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Mayank Garg, Nicole Pamme
Summary: This review focuses on the removal strategies of templates from molecularly imprinted polymers (MIPs) used in diagnostic biosensors. Chemical-based and electrochemical-based template extraction approaches are summarized and evaluated, providing guidance for researchers in the fields of analytical chemistry, diagnostics, and materials science for the design of MIP-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Ivneet Banga, Anirban Paul, Nathan Kodjo Mintah Churcher, Ruchita Mahesh Kumar, Sriram Muthukumar, Shalini Prasad
Summary: Breathomics is an emerging field that focuses on analyzing exhaled breath to diagnose and monitor respiratory diseases. Electrochemical sensors, with their high sensitivity, selectivity, and low cost, play a significant role in breathomics and can be integrated into portable devices for point-of-care diagnosis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Fabjola Bilo, Paola Cirelli, Laura Borgese
Summary: This review explores the application of X-ray fluorescence (XRF) spectrometry for elemental analysis of particulate matter (PM) in air quality monitoring. It discusses the fundamentals of XRF, experimental configurations, PM sampling devices and substrate, sample preparation strategies, qualitative and quantitative analysis, as well as the challenges faced by XRF in becoming a reliable analytical technique for PM analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hakim Faraji
Summary: The dispersive liquid-liquid microextraction (DLLME) technique is widely popular in analytical chemistry due to its high efficiency, cost-effectiveness, and simplicity. Recent advancements have addressed the limitations of DLLME, incorporating greener solvents, innovative dispersion strategies, and simplified procedures. These changes have made DLLME a more sustainable and efficient technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair, Reda M. Abdelhameed, Marcello Locatelli, Fotouh R. Mansour
Summary: Carbon nanomaterials (CNMs) have excellent capabilities in terms of adsorption, enhanced oxidation, and photocatalysis, attracting widespread attention in different fields. Metal-organic frameworks (MOFs) have been widely used due to their regular network structure, porous nature, and large specific surface area. However, the instability of MOFs in aqueous solutions limits their applications in chemical sensing. Recent studies have focused on increasing the stability of MOFs in water-based matrices through chemical modifications using CNMs.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Alexandra Pape, Oliver J. Schmitz
Summary: Low temperature plasmas based on dielectric barrier discharges have emerged as a recent development in ion source research. These ion sources are applicable to heat-sensitive analytes and can ionize a wide range of compounds. Despite intensive research on important parameters such as configuration, shape, size, and materials in the past two decades, the actual ionization mechanism for all plasma gases has not been fully elucidated. This review provides an overview of atmospheric pressure ion sources, with a focus on plasma and dielectric barrier discharge based ion sources, summarizing the reactions occurring in the plasma and discussing the applications developed by different research groups.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hai Xiong, Fengli Li, Linyu Zeng, Qiyu Lei
Summary: This review provides an overview of the emerging trends in the use of functional COF nanomaterials as biosensors for DNA/RNA detection. It summarizes the construction of DNA/RNA hybridized COF nanoprobes and their potential applications in bioanalyte detection, biosensing, biomarker imaging, and clinical biomedicine.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Bing Yan
Summary: This article summarizes the recent progress in logic gate computing and operation based on multiple luminescence response and chemical sensing for lanthanide functionalized MOF hybrid systems. The article first describes multi-color luminescence and the subsequent multiple luminescence response. The basic concept of logic gate operation and the advantages of lanthanide-based hybrid materials are then introduced. Reports on logic gate operation using pure lanthanide MOFs are provided, followed by a detailed summary of logic gate operations using lanthanide functionalized MOF hybrid materials. Additionally, the article discusses the practical luminescent detection of analytes by correlating the luminescence responsive signals and the concentration of different analytes. Finally, the article concludes with a prospect for this topic.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Brij Mohan, Gurjaspreet Singh, Rakesh Kumar Gupta, Pawan Kumar Sharma, Alexander A. Solovev, Armando J. L. Pombeiro, Peng Ren
Summary: Porous materials, particularly hydrogen-bonded organic frameworks (HOFs), have gained significant attention due to their versatile applications and unique properties such as well-defined crystalline structure and easy regeneration processes. This article provides a comprehensive overview of HOFs, including synthesis methods, hydrogen bonding motifs, recent advancements, and potential applications, offering valuable guidance for further exploration in this dynamic field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
