RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo

Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide

(2014) Eva Madi Riising et al.   MOLECULAR CELL

Epigenetic Modifications Induced by Blimp-1 Regulate CD8+ T Cell Memory Progression during Acute Virus Infection

(2013) Hyun Mu Shin et al.   IMMUNITY

Identification of Small Molecule Inhibitors of Jumonji AT-rich Interactive Domain 1B (JARID1B) Histone Demethylase by a Sensitive High Throughput Screen

(2013) Joyce Sayegh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy-Inducing Protein Beclin-1 in Dendritic Cells Regulates CD4 T Cell Responses and Disease Severity during Respiratory Syncytial Virus Infection

(2013) M. Reed et al.   JOURNAL OF IMMUNOLOGY

Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration

(2013) Sihyug Jang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interferon-Beta Induces Distinct Gene Expression Response Patterns in Human Monocytes versus T cells

(2013) Noa Henig et al.   PLoS One

The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

(2013) Mareike Albert et al.   PLoS Genetics

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

(2012) Line H. Kristensen et al.   FEBS Journal

Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response

(2012) Terry C. Fang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Respiratory Syncytial Virus NS1 Protein Colocalizes with Mitochondrial Antiviral Signaling Protein MAVS following Infection

(2012) Sandhya Boyapalle et al.   PLoS One

DNA methylation: a promising landscape for immune system-related diseases

(2012) Beatriz Suarez-Alvarez et al.   TRENDS IN GENETICS

Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)

(2012) Elizabeth C Moore et al.   Virology Journal

Jarid1b targets genes regulating development and is involved in neural differentiation

(2011) Sandra U Schmitz et al.   EMBO JOURNAL

H3K4 tri-methylation provides an epigenetic signature of active enhancers

(2011) Aleksandra Pekowska et al.   EMBO JOURNAL

Differential Pathogenesis of Respiratory Syncytial Virus Clinical Isolates in BALB/c Mice

(2011) K. L. Stokes et al.   JOURNAL OF VIROLOGY

Regulation of STAT signaling in mouse bone marrow derived dendritic cells by respiratory syncytial virus

(2011) Zhijun Jie et al.   VIRUS RESEARCH

Epigenomic deregulation in the immune system

(2011) Virginia C Rodriguez-Cortez et al.   Epigenomics

Respiratory Syncytial Virus Interferon Antagonist NS1 Protein Suppresses and Skews the Human T Lymphocyte Response

(2011) Shirin Munir et al.   PLoS Pathogens

Epigenetic modulation of host: new insights into immune evasion by viruses

(2010) Dwaipayan Adhya et al.   JOURNAL OF BIOSCIENCES

Respiratory Virus-Induced TLR7 Activation Controls IL-17-Associated Increased Mucus via IL-23 Regulation

(2010) N. W. Lukacs et al.   JOURNAL OF IMMUNOLOGY

Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

(2009) Gang Wei et al.   IMMUNITY

Subversion of Pulmonary Dendritic Cell Function by Paramyxovirus Infections

(2009) A. Guerrero-Plata et al.   JOURNAL OF IMMUNOLOGY

Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I

(2009) Z. Ling et al.   JOURNAL OF VIROLOGY

Soluble G protein of respiratory syncytial virus inhibits Toll-like receptor 3/4-mediated IFN-beta induction

(2008) M. Shingai et al.   INTERNATIONAL IMMUNOLOGY

Nonstructural Proteins 1 and 2 of Respiratory Syncytial Virus Suppress Maturation of Human Dendritic Cells

(2008) S. Munir et al.   JOURNAL OF VIROLOGY

Division of labor between dendritic cell subsets of the lung

(2008) C H GeurtsvanKessel et al.   Mucosal Immunology