Structural Determinants of Phenotypic Diversity and Replication Rate of Human Prions

Parallel In-register Intermolecular β-Sheet Architectures for Prion-seeded Prion Protein (PrP) Amyloids

(2014) Bradley R. Groveman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Stability of Mammalian Prion Protein Amyloid Fibrils Is Dictated by a Packing Polymorphism within the Core Region

(2013) Nathan J. Cobb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-existence of Distinct Prion Types Enables Conformational Evolution of Human PrPScby Competitive Selection

(2013) Tracy Haldiman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cofactor Molecules Induce Structural Transformation during Infectious Prion Formation

(2013) Michael B. Miller et al.   STRUCTURE

Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA

(2012) Piero Parchi et al.   ACTA NEUROPATHOLOGICA

Sporadic human prion diseases: molecular insights and diagnosis

(2012) Gianfranco Puoti et al.   LANCET NEUROLOGY

Biochemical Properties of Highly Neuroinvasive Prion Strains

(2012) Cyrus Bett et al.   PLoS Pathogens

Small Protease Sensitive Oligomers of PrPSc in Distinct Human Prions Determine Conversion Rate of PrPC

(2012) Chae Kim et al.   PLoS Pathogens

Slow Histidine H/D Exchange Protocol for Thermodynamic Analysis of Protein Folding and Stability Using Mass Spectrometry

(2011) Duc T. Tran et al.   ANALYTICAL CHEMISTRY

Amyloid Structure: Conformational Diversity and Consequences

(2011) Brandon H. Toyama et al.   Annual Review of Biochemistry

Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange

(2011) Vytautas Smirnovas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histidine Hydrogen-Deuterium Exchange Mass Spectrometry for Probing the Microenvironment of Histidine Residues in Dihydrofolate Reductase

(2011) Masaru Miyagi et al.   PLoS One

The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

(2011) Jacob I. Ayers et al.   PLoS Pathogens

Protease-Sensitive Conformers in Broad Spectrum of Distinct PrPSc Structures in Sporadic Creutzfeldt-Jakob Disease Are Indicator of Progression Rate

(2011) Chae Kim et al.   PLoS Pathogens

Molecular biology and pathology of prion strains in sporadic human prion diseases

(2010) Pierluigi Gambetti et al.   ACTA NEUROPATHOLOGICA

Molecular pathology of human prion disease

(2010) Jonathan D. F. Wadsworth et al.   ACTA NEUROPATHOLOGICA

Human prion strain selection in transgenic mice

(2010) Kurt Giles et al.   ANNALS OF NEUROLOGY

Defining sporadic Creutzfeldt-Jakob disease strains and their transmission properties

(2010) M. T. Bishop et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt–Jakob disease: its effect on the phenotype and prion-type characteristics

(2009) Ignazio Cali et al.   BRAIN

Distinct Structures of Scrapie Prion Protein (PrPSc)-seededVersusSpontaneous Recombinant Prion Protein Fibrils Revealed by Hydrogen/Deuterium Exchange

(2009) Vytautas Smirnovas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design and construction of diverse mammalian prion strains

(2009) D. W. Colby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of pKaValues of Individual Histidine Residues in Proteins Using Mass Spectrometry

(2008) Masaru Miyagi et al.   ANALYTICAL CHEMISTRY

Rapidly progressive dementia

(2008) Michael D. Geschwind et al.   ANNALS OF NEUROLOGY

Cell-free propagation of prion strains

(2008) Joaquín Castilla et al.   EMBO JOURNAL

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

(2008) Ryuichiro Atarashi et al.   NATURE METHODS

Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice

(2008) J. D. F. Wadsworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond PrPres Type 1/Type 2 Dichotomy in Creutzfeldt-Jakob Disease

(2008) Emmanuelle Uro-Coste et al.   PLoS Pathogens