Article
Microbiology
Gongwen Chen, Yuqi Wu, Jie Deng, Zhengsheng Wen, Shuai Wang, Yanping Chen, Fuliang Hu, Huoqing Zheng
Summary: Keeping colonies of both western honey bees and eastern honey bees in close proximity in China increases opportunities for parasite and pathogen spillover. A large-scale survey conducted over a year revealed common viral infections in both bee species, with differences in infection dynamics between bee species or seasons. Varroa destructor infestation may contribute to the high susceptibility of A. mellifera to certain viruses, while others pose a greater threat to A. cerana. Cross-regional and cross-species spread of viruses was suggested by phylogenetic analyses, highlighting the need for effective disease management strategies to improve bee health.
Article
Environmental Sciences
Lais V. B. Inoue, Caio E. C. Domingues, Ales Gregorc, Elaine C. M. Silva-Zacarin, Osmar Malaspina
Summary: This study aimed to investigate the effects of the fungicide pyraclostrobin on the fat body and pericardial cells of Africanized honey bees. The results showed that pyraclostrobin can harm colony production and survival by causing detrimental effects at the individual bee cellular level.
Article
Environmental Sciences
Ge Zhang, Miranda Kersten, Amy Owen, Amanda Skidmore
Summary: The negative impacts of industrial farming on honey bee health, such as pesticide use and habitat loss, are well-known. Evaluating the suitability of urban farms for honey bee health is crucial for sustainable agriculture and apiculture in urban settings. Organic urban farms with restrictions on synthetic pesticides and conservation of natural habitat can provide an environment that mitigates these stressors. This experiment found that honey bees on organic urban farms in New Mexico were not stressed by pesticides, had diverse forage resources, and thrived with certain hive equipment. Overall, organic urban farms are important for honey bee health and food safety in desert climates, and hive equipment selection plays a role in mitigating environmental stress.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Entomology
Julio Chavez-Galarza, Ruth Lopez-Montanez, Alejandra Jimenez, Ruben Ferro-Mauricio, Juan Ore, Sergio Medina, Reyna Rea, Hector Vasquez
Summary: The genetic diversity of Peruvian honey bee populations remains unknown, with 65% of colonies belonging to African lineage A, 33.8% to Eastern European lineage C, and 1.2% to Western European lineage M. This study identified 24 haplotypes, including 15 reported for the first time, with Piura and Lima showing higher proportions of African haplotypes compared to European haplotypes, especially lineage C. Colonies from lineage M were rare and may indicate accidental introductions in the 19th century. Further studies are needed for sustainable management and conservation efforts.
Article
Multidisciplinary Sciences
Yuqi Wu, Yufei Zheng, Shuai Wang, Yanping Chen, Junyi Tao, Yanan Chen, Gongwen Chen, Hongxia Zhao, Kai Wang, Kun Dong, Fuliang Hu, Ye Feng, Huoqing Zheng
Summary: The intra-species diversity of gut microbiota in two closely related honey bee species, A. cerana and A. mellifera, shows distinct functional differences in core bacterial species between the hosts. However, the overall functional profiles of the gut microbiomes of the two honey bee species converge, likely due to overlapping ecological niches. This study provides critical insights into the evolution and functional roles of mutualistic microbiota in honey bees.
JOURNAL OF ADVANCED RESEARCH
(2022)
Article
Ecology
Cameron J. Jack, Ivone de Bem Oliveira, Chase B. Kimmel, James D. Ellis
Summary: Varroa destructor poses a significant threat to the global apiculture industry. Effective control of this parasite requires timely treatment. In order to understand the impact of treatment timing on Varroa populations in different seasons, we conducted a study using two field trials over multiple years in Florida, USA. Our results show that the efficacy of Varroa treatments varies across seasons, with faster population growth in summer and fall compared to winter and spring.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2023)
Review
Entomology
Dayson Castilhos, Alana Maria Polesso, Alany Cristyane Felix da Silva, Alexsandro Bispo dos Santos, Alice Tamara de Carvalho Lopes, Aloisio Alkimim de Oliveira Filho, Ana Flavia Santos da Cunha, Anderson Puker, Andre Luis Matioli, Andrea Abreu Serrado Campos, Andreia Lopes de Morais, Anna Frida Hatsue Modro, Antonio Abreu Silveira Neto, Arthur de Souza Moreira Pires, Caio Biasi, Carine Mascena Peixoto, Carize da Cruz Merces, Carlos Alfredo Lopes de Carvalho, Charle da Silva Paiva, Daniel Santiago Pereira, Daniel Santos Freire, Darcet Costa Souza, David De Jong, Diego Antonio Machado Soares, Edgar Rodrigues de Araujo Neto, Eduardo Alves de Souza, Eliaber Barros Santos, Emanuel Maia, Endrigo Adonis Braga de Araujo, Erica Gomes Lima, Erica Weinstein Teixeira, Erika Gleice Menezes do Nascimento, Fabio Adriano E Silva, Fabricio Alaor Cappelari, Fabricio Chagas Sobrinho, Felipe Mendes Fontes, Francisco Ariclenes Olinto, Francisco Everton Jales da Silva, Genevile Carife Bergamo, Geraldo Aparecido Rodrigues, Geraldo Moretto, Giliola Maria Lima Casadio, Gilson Marcos Bogus, Gleidson Giordano Pinto de Carvalho, Gleydson Luiz de Oliveira Neto, Guido Castagnino, Guilherme Sampaio de Queiroz, Gustavo Porfirio Pires, Hemilly Marques da Silva, Hilton Borges Silva Neto, Hugo Thales de Souza Nunes, Ingrid Pereira Pinto Oliveira, Isadora Rodriguez Sambrana, Jean Samel Rocha, Jefferson Luiz Bandero, Joao Gustavo Souza Sales de Albuquerque, Joao Paulo de Holanda Neto, John Kastelic, Jose Carlos Vieira Guerra Junior, Joselly Rodrigues da Costa, Jossivanio Santos de Jesus, Juliana Bendini, Katia Peres Gramacho, Larissa Souza, Lavinia Nascimento Leoni, Lionel Segui Goncalves, Lubiane Guimaraes Cestaro, Lucas da Silva Morais, Lucas Filipe Correia Franca Dantas, Luciano Santana Serra, Lucilene de Abreu, Luis Carlos Borsuk, Luis Fernando Batista Pinto, Luiz Amilo da Silva, Luiz Arthur dos Anjos Lima, Maicon Jose Fogaca, Marcia Regina Cavichio Issa, Maria Emilene Correia-Oliveira, Maria Luisa Teles Marques Florencio Alves, Marliton Rocha Barreto, Matheus Carvalho Del Rey, Matheus Jose de Oliveira Costa Barbosa, Matheus Roberto da Silva, Michelle Manfrini Morais, Natalia Vinhal-Silva, Pamela Tereza de Oliveira Gomes, Patricia Mendes Guimaraes-Beelen, Patrick Oliveira de Sousa, Paulo Sergio Cavalcanti Costa, Pedro Acioli de Souza, Rafael de Paula, Raiane Barbosa Mendes, Renata Valeria Regis de Sousa Gomes, Ricardo Goncalves Santos, Roberto Junior Teixeira Nascimento, Rodrigo Diniz Silveira, Rodrigo Silva Cabral, Rodrigo Torres, Roger Beelen, Rogerio Aparecido Pereira, Romulo Augusto Guedes Rizzardo, Sabrina Aparecida Cunha, Sandro Tarcisio Celmer, Sarajane Estevan, Sebastiao Lourenco de Assis Junior, Silel Vinicius Simoes Andrade Maciel, Silvio Jose Reis da Silva, Stephano Moreira, Tania Patricia Schafaschek, Tatiane Amaral de Barros, Tayana Holz Ruela, Thais Menezes de Souza Vitena, Thais Regina Bridi, Vagner Maximino Leite, Vanderlei Doniseti Acassio dos Reis, Vanessa Santos Louzado das Neves, Viviane Ferreira de Medeiros
Summary: The dynamics of Varroa destructor infestation levels in Africanized honey bees (AHB) in Brazil were examined in this review article. The study found that there were no indications that varroa negatively impacted Brazilian apiculture, despite significant variations in mite infestations over the past 45 years. The average infestation levels have remained around 4.5 mites per 100 adult bees, with a median of 3.8. Factors such as climate, hybridization, grooming and hygienic behaviors, genetic factors, stress levels, management practices, and environmental conditions were suggested to contribute to the low infestation levels.
Review
Entomology
Thomas D. Seeley
Summary: Thomas Seeley's research focuses on collective intelligence and natural lives of honey bees. By studying their behavior and social life, he reveals how a honey bee colony functions as a single decision-making unit in the wild.
ANNUAL REVIEW OF ENTOMOLOGY
(2022)
Article
Entomology
Daniel Cook, Boyd Tarlinton, James M. McGree, Alethea Blackler, Caroline Hauxwell
Summary: Strength auditing of European honey bee colonies is critical for colony health management. This study evaluates the use of temperature sensing technology in colony strength assessment and identifies key parameters linking temperature to colony strength. The presence of bees in hives significantly affects hive temperature and range, and sensor placement across the width of the hive is important when linking sensor data with colony strength. Statistical models can be used to predict colony strength from temperature sensor data.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Immunology
Alexandre Naime Barbosa, Rui Seabra Ferreira, Francilene Capel Tavares de Carvalho, Fabiana Schuelter-Trevisol, Monica Bannwart Mendes, Bruna Cavecci Mendonca, Jose Nixon Batista, Daisson Jose Trevisol, Leslie Boyer, Jean-Philippe Chippaux, Natalia Bronzatto Medolago, Claudia Vilalva Cassaro, Marcia Tonin Rigotto Carneiro, Ana Paola Piloto de Oliveira, Daniel Carvalho Pimenta, Luis Eduardo Ribeiro da Cunha, Lucilene Delazari dos Santos, Benedito Barraviera
Summary: The study evaluated the safety, optimal dose, and preliminary effectiveness of a new Africanized honeybee antivenom in treating multiple stings. Results showed the antivenom to be safe and effective in treating massive bee attacks, with participants experiencing rapid recovery and significant decrease in venom levels during treatment.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Entomology
Adam Tofilski, Eliza Cauia, Adrian Siceanu, Gabriela Oana Visan, Dumitru Cauia
Summary: The study revealed significant changes in wing venation of Romanian honey bees over the past four decades, but the two major subpopulations separated by mountains remain distinct. This suggests that natural variation among honey bees is still preserved despite hybridization between native and non-native bees. To aid in the conservation efforts, a method for identifying native Romanian bees was developed.
Article
Multidisciplinary Sciences
Szymon Smolinski, Aleksandra Langowska, Adam Glazaczow
Summary: The study revealed that elevated temperatures in spring and autumn reinforce the infestation of V. destructor in bee colonies. Factors such as bee abundance, capped brood abundance in autumn, and the number of colonies merged have significant effects on autumn mite infestation.
SCIENTIFIC REPORTS
(2021)
Article
Microbiology
Kirk J. Grubbs, Daniel S. May, Joseph A. Sardina, Renee K. Dermenjian, Thomas P. Wyche, Adrian A. Pinto-Tomas, Jon Clardy, Cameron R. Currie
Summary: Research suggests that honey bees may use Actinobacteria derived from pollen and their associated small molecules to maintain colony health, particularly exhibiting inhibitory activity against Paenibacillus larvae, the causative agent of American foulbrood.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Ashley L. St Clair, Ge Zhang, Adam G. Dolezal, Matthew E. O'Neal, Amy L. Toth
Summary: Large scale agricultural production can reduce habitat availability for wild bees and lead to population declines. The presence of managed honey bee colonies may not have an immediate negative impact on wild bees. Instead, wild bees respond strongly to landscape composition, with lower species richness in landscapes dominated by crops. Woodland and grassland habitats have the greatest positive effect on bee richness.
AGRICULTURE ECOSYSTEMS & ENVIRONMENT
(2022)
Article
Entomology
Abdessamad Aglagane, Adam Tofilski, Omar Er-Rguibi, El-Mustapha Laghzaoui, Latifa Kimdil, El Hassan El Mouden, Stefan Fuchs, Andrzej Oleksa, Ahmed Aamiri, Mohamed Aourir
Summary: This study investigates the conservation status and geographic variation of four populations of Apis mellifera sahariensis in south-eastern Morocco using geometric morphometrics. The study finds significant differences between the studied populations and the reference subspecies, likely due to hybridization. The study also identifies significant differences in wing shape among the four populations, attributed to the fragmented distribution of the study area. These findings can inform future conservation strategies for the Saharan honey bee in Morocco.
Article
Entomology
Marcelo P. Camilli, Daniel C. B. de Barros, Gabriel M. Martineli, Aime A. Longuini, Samir Moura Kadri, Jose Cavalcante S. Vieira, Pedro de Magalhaes Padilha, Ricardo de Oliveira Orsi
Summary: This study examined the effects of supplementation with different concentrations of organic zinc on the proteome of royal jelly in Apis mellifera. The results showed that the organic zinc-containing diets altered the protein content and expression of major royal jelly proteins.
JOURNAL OF APICULTURAL RESEARCH
(2023)
Article
Critical Care Medicine
Ana Paula Silveira Leite, Carina Guidi Pinto, Felipe Cantore Tiburcio, Kevin Silva Muller, Carlos Roberto Padovani, Benedito Barraviera, Rui Seabra Ferreira Junior, Claudenete Vieira Leal, Cintia Yuri Matsumura, Selma Maria Michelin Matheus
Summary: Peripheral nerve injuries lead to changes in the Agrin-LRP4-MuSK pathway, resulting in disaggregation of AChRs and a shift from epsilon to gamma subunit. This study evaluated the effect of combining tubulization with fibrin biopolymer on AChRs and associated proteins after peripheral nerve injury. The results showed that the tubulization with fibrin biopolymer group exhibited morphological and morphometric similarities to the control group at the neuromuscular junctions. Additionally, there was an increase in S100 and AChR epsilon protein expression, and a decrease in MyoD expression. These positive associations enhanced AChRs stabilization and promoted neuromuscular regeneration, highlighting the potential of tubulization for severe injury repair and the beneficial effect of fibrin biopolymer.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2023)
Article
Biochemistry & Molecular Biology
Karina Torres Pomini, Daniela Vieira Buchaim, Ana Carolina Cestari Bighetti, Abdul Latif Hamze, Carlos Henrique Bertoni Reis, Marco Antonio Hungaro Duarte, Murilo Priori Alcalde, Benedito Barraviera, Rui Seabra Ferreira Junior, Alexandre Teixeira de Souza, Paulo Sergio da Silva Santos, Joao Paulo Galletti Pilon, Miguel Angelo de Marchi, Dayane Maria Braz Nogueira, Cleuber Rodrigo de Souza Bueno, Wendel Cleber Soares, Rogerio Leone Buchaim
Summary: Extending the use of heterologous fibrin biopolymer, this pre-clinical study examined the formation of a less dense scaffold to facilitate bone cell infiltration by adjusting the proportionality of its components. Combined with laser photobiomodulation therapy, it aimed to accelerate the repair process and reduce recovery time. The study found that the laser-treated groups showed higher bone volume and bone area, indicating the potential effects of laser radiation in promoting bone regeneration.
Article
Biochemical Research Methods
Emidio Beraldo-Neto, Hugo Vigerelli, Guilherme Rabelo Coelho, Daiane Laise da Silva, Ana Leonor Abrahao Nencioni, Daniel Carvalho Pimenta
Summary: Tityus bahiensis, a scorpion species found in Brazil, has been identified as one of the main causes of human accidents. However, the composition of its venom has not been described in the literature, leading to a lack of proper study on this particular species. In this study, chromatographic separation and proteomic analyses were conducted to investigate the peptides and proteins present in the scorpion venom. The results revealed a diverse range of toxins and enzymes, including potassium and sodium channel toxins, metallopeptidases, hyaluronidases, phospholipase, angiotensin-converting enzyme, cysteine-rich proteins, serine peptidase inhibitors peptides, and antimicrobial peptides. This study provides valuable insights into the diversity and distribution of venom toxins and introduces a straightforward method for venom fractionation.
JOURNAL OF PROTEOMICS
(2023)
Article
Clinical Neurology
Felipe Cantore Tiburcio, Kevin Silva Muller, Ana Paula Silveira Leite, Igor Rodrigues Araujo de Oliveira, Benedito Barraviera, Rui Seabra Ferreira Jr, Carlos Roberto Padovani, Carina Guidi Pinto, Selma Maria Michelin Matheus
Summary: This study evaluated the neuroregeneration and immune response using suture-associated heterologous fibrin biopolymer (HFB) for sciatic nerve repair. The results showed that HFB increased axonal regeneration, induced angiogenesis, prevented severe muscle degeneration, and assisted in neuromuscular junction recovery, which has significant implications for improved peripheral nerve repair.
Article
Entomology
Giovanna do Prado Ribeiro, Samir Moura Kadri, Luis Antonio Justulin, Paulo Eduardo Martins Ribolla, Ricardo de Oliveira Orsi
Summary: This study analyzed whether the source of zinc (inorganic and organic) affects the morphology of the hypopharyngeal gland (HPG) and the relative expression of major royal jelly protein (MRJP) genes in nursing bees. The results showed that zinc increased the HPG area, but did not significantly affect the expression of MRJP genes. Organic source of zinc had the best results.
PHYSIOLOGICAL ENTOMOLOGY
(2023)
Review
Food Science & Technology
Lais Campelo Mendes, Gabriela Magnolia Melo Viana, Ana Leonor Abrahao Nencioni, Daniel Carvalho Pimenta, Emidio Beraldo-Neto
Summary: The scorpion family Buthidae includes arthropods whose venom contains diverse biomolecules, including neurotoxins that target ion channels in cell membranes. Disturbances in ion channel activity can lead to channelopathies, causing a range of diseases. Scorpion peptides offer potential as resources for developing drugs that specifically target ion channels. This review provides a comprehensive overview of ion channels, scorpion toxins, and potential areas for future research, emphasizing the significance of scorpion venom in discovering novel drugs for treating channelopathies.
Review
Food Science & Technology
Joeliton dos Santos Cavalcante, Denis Emanuel Garcia de Almeida, Micael Saggion Moraes, Sophia Ribeiro Santos, Pedro Moriel Pincinato, Pedro Marques Riciopo, Lais Lacerda B. de Oliveira, Wuelton Marcelo Monteiro, Rui Seabra Ferreira-Junior
Summary: Specific and sensitive tools for diagnosing and monitoring accidents caused by venomous animals are urgently needed. Existing diagnostic methods have not yet been applied in clinical settings, resulting in delayed diagnoses and progression to severe disease.
Article
Chemistry, Medicinal
Cleuber Rodrigo de Souza Bueno, Maria Clara Cassola Tonin, Daniela Vieira Buchaim, Benedito Barraviera, Rui Seabra Ferreira Jr, Paulo Sergio da Silva Santos, Carlos Henrique Bertoni Reis, Claudio Maldonado Pastori, Eliana de Souza Bastos Mazuqueli Pereira, Dayane Maria Braz Nogueira, Marcelo Augusto Cini, Geraldo Marco Rosa Jr, Rogerio Leone Buchaim
Summary: This study investigated the use of heterologous fibrin biopolymer (HFB) in the repair of the buccal branch of the facial nerve (BBFN) along with photobiomodulation (PBM) using low-level laser therapy (LLLT). The effects on axons, facial muscles, and functional recovery were analyzed.
Article
Chemistry, Medicinal
Daiane Laise da Silva, Rodrigo Valladao, Emidio Beraldo-Neto, Guilherme Rabelo Coelho, Oscar Bento da Silva Neto, Hugo Vigerelli, Adriana Rios Lopes, Brett R. Hamilton, Eivind A. B. Undheim, Juliana Mozer Sciani, Daniel Carvalho Pimenta
Summary: In this study, three serine peptidase inhibitors were isolated from the venom of the Brazilian sea anemone A. cascaia. These inhibitors were found to belong to the venom Kunitz toxin family and may play a role in protecting other venom components from proteolysis. Mass spectrometry imaging revealed the spatial distribution of these inhibitors throughout the sea anemone.
Article
Biochemistry & Molecular Biology
Adelia Cristina Oliveira Cintra, Tassia Rafaella Costa, Gabriel Neves Cezarette, Fabiola Attie de Castro, Daniel Carvalho Pimenta, Suely Vilela Sampaio
Summary: Venom peptides from Bothrops atrox snake venom, particularly the novel peptide Batroxin I, showed selective cytotoxicity towards HepG2 liver tumor cells and induced apoptosis by intrinsic pathway activation. The amino acid sequence of Batroxin I was determined and it belonged to the class of bradykinin-enhancing peptides and cell penetration peptide. This peptide could potentially be used as a template for drug development and as an adjuvant to treat cancer and other diseases.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2023)
Article
Chemistry, Applied
Camilla Nicolucci, Milena Padovani, Fernanda de Castro Rodrigues, Laura Nagy Fritsch, Ana Cristina Santos, Denise Goncalves Priolli, Juliana M. Sciani
Summary: Flavonoids, with antioxidant, anti-inflammatory, and neuroprotective properties, have potential therapeutic effects on central nervous system diseases such as Alzheimer's disease and Parkinson's disease. They protect neurons, improve brain function, and modulate neurotransmission for treating mental disorders like sedative, antidepressant, and sleep inducer. Research on the mechanisms and benefits of flavonoids is ongoing, but they represent a promising avenue for future research and development.
NATURAL PRODUCT RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Mohammadhossein Movassaghghazani, Nazanin Shabansalmani
Summary: The study revealed high levels of AFM1 in both breast milk and powdered milk samples in Tehran, with some samples exceeding the established limits. Therefore, monitoring and regulating toxin levels in these products is crucial for maternal and infant health.
Article
Pharmacology & Pharmacy
Defeng Wen, Wantong Han, Quan Chen, Guanhui Qi, Mengling Gao, Pu Guo, Yu Liu, Zhongyuan Wu, Shulin Fu, Qirong Lu, Yinsheng Qiu
Summary: Luteolin can inhibit FB1-induced intestinal inflammatory injury by inhibiting the activation of NF-kappa B and ERK signaling pathways, according to network pharmacology and in vitro experiments.
