Infrared Fluorescent Imaging as a Potent Tool for In Vitro, Ex Vivo and In Vivo Models of Visceral Leishmaniasis

Projects set to tackle neglected diseases

(2014) Erika Check Hayden   NATURE

Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?

(2014) Rosa M. Reguera et al.   International Journal for Parasitology-Drugs and Drug Resistance

Antileishmanial Activity, Uptake, and Biodistribution of an Amphotericin B and Poly(α-Glutamic Acid) Complex

(2013) Abeer H. A. Mohamed-Ahmed et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

(2013) Manu De Rycker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An alternative in vitro drug screening test using Leishmania amazonensis transfected with red fluorescent protein

(2013) Marcele N. Rocha et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Appraisal of a Leishmania major Strain Stably Expressing mCherry Fluorescent Protein for Both In Vitro and In Vivo Studies of Potential Drugs and Vaccine against Cutaneous Leishmaniasis

(2012) Estefania Calvo-Álvarez et al.   PLoS Neglected Tropical Diseases

An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages

(2012) Jair L. Siqueira-Neto et al.   PLoS Neglected Tropical Diseases

Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it?

(2012) Lucio H. Freitas-Junior et al.   International Journal for Parasitology-Drugs and Drug Resistance

Improvement of the green fluorescent protein reporter system in Leishmania spp. for the in vitro and in vivo screening of antileishmanial drugs

(2011) Sergio A. Pulido et al.   ACTA TROPICA

Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation

(2011) Pascale Pescher et al.   CELLULAR MICROBIOLOGY

Bright and stable near-infrared fluorescent protein for in vivo imaging

(2011) Grigory S Filonov et al.   NATURE BIOTECHNOLOGY

Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System

(2011) Yaneth Osorio et al.   PLoS Neglected Tropical Diseases

Imaging of the host/parasite interplay in cutaneous leishmaniasis

(2010) Owain R. Millington et al.   EXPERIMENTAL PARASITOLOGY

Fluorescent Leishmania species: Development of stable GFP expression and its application for in vitro and in vivo studies

(2010) Azam Bolhassani et al.   EXPERIMENTAL PARASITOLOGY

In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent

(2010) K. Seifert et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Transgenic Leishmania donovani clinical isolates expressing green fluorescent protein constitutively for rapid and reliable ex vivo drug screening

(2009) N. Singh et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mammalian Expression of Infrared Fluorescent Proteins Engineered from a Bacterial Phytochrome

(2009) X. Shu et al.   SCIENCE

Reporter genes facilitating discovery of drugs targeting protozoan parasites

(2009) Anuradha Dube et al.   TRENDS IN PARASITOLOGY

Bioluminescent Imaging of Trypanosoma brucei Shows Preferential Testis Dissemination Which May Hamper Drug Efficacy in Sleeping Sickness

(2009) Filip Claes et al.   PLoS Neglected Tropical Diseases

Real-Time In Vivo Green Fluorescent Protein Imaging of a Murine Leishmaniasis Model as a New Tool for Leishmania Vaccine and Drug Discovery

(2008) S. R. Mehta et al.   Clinical and Vaccine Immunology