Interaction between the tRNA-Binding and C-Terminal Domains of Yeast Gcn2 Regulates Kinase Activity In Vivo

Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals

(2014) Hongzhen He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Initiation Factor eIF2 in Response to Stress Conditions Is Mediated by Acidic Ribosomal P1/P2 Proteins in Saccharomyces cerevisiae

(2014) Antonio Jiménez-Díaz et al.   PLoS One

Enhanced Interaction between Pseudokinase and Kinase Domains in Gcn2 stimulates eIF2α Phosphorylation in Starved Cells

(2014) Sebastien Lageix et al.   PLoS Genetics

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

(2013) James M. Murphy et al.   BIOCHEMICAL JOURNAL

EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension

(2013) Mélanie Eyries et al.   NATURE GENETICS

New functions of protein kinase Gcn2 in yeast and mammals

(2012) José R. Murguía et al.   IUBMB LIFE

Overexpression of Eukaryotic Translation Elongation Factor 3 Impairs Gcn2 Protein Activation

(2012) Jyothsna Visweswaraiah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence That Eukaryotic Translation Elongation Factor 1A (eEF1A) Binds the Gcn2 Protein C Terminus and Inhibits Gcn2 Activity

(2011) Jyothsna Visweswaraiah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs

(2010) Ethan A. Merritt et al.   JOURNAL OF MOLECULAR BIOLOGY