An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies
出版年份 2015 全文链接
标题
An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies
作者
关键词
Genome-wide association studies, Meta-analysis, Schizophrenia, Crohns disease, Test statistics, Genetic loci, Normal distribution, Molecular genetics
出版物
PLoS Genetics
Volume 11, Issue 12, Pages e1005717
出版商
Public Library of Science (PLoS)
发表日期
2015-12-30
DOI
10.1371/journal.pgen.1005717
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies
- (2013) Nilanjan Chatterjee et al. NATURE GENETICS
- Polygenic Modeling with Bayesian Sparse Linear Mixed Models
- (2013) Xiang Zhou et al. PLoS Genetics
- All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs
- (2013) Andrew J. Schork et al. PLoS Genetics
- Improved Heritability Estimation from Genome-wide SNPs
- (2012) Doug Speed et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
- (2012) S Hong Lee et al. NATURE GENETICS
- Genome-wide efficient mixed-model analysis for association studies
- (2012) Xiang Zhou et al. NATURE GENETICS
- Estimating Missing Heritability for Disease from Genome-wide Association Studies
- (2011) Sang Hong Lee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genomic inflation factors under polygenic inheritance
- (2011) Jian Yang et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Genome-wide association studies establish that human intelligence is highly heritable and polygenic
- (2011) G Davies et al. MOLECULAR PSYCHIATRY
- Genome-wide association study identifies five new schizophrenia loci
- (2011) NATURE GENETICS
- Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants
- (2011) J.-H. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A flexible genome-wide bootstrap method that accounts for rankingand threshold-selection bias in GWAS interpretation and replication study design
- (2011) Laura L. Faye et al. STATISTICS IN MEDICINE
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
- (2010) Ju-Hyun Park et al. NATURE GENETICS
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
- Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
- (2010) Andre Franke et al. NATURE GENETICS
- Estimating Effects and Making Predictions from Genome-Wide Marker Data
- (2010) Michael E. Goddard et al. STATISTICAL SCIENCE
- Estimating the posterior probability that genome-wide association findings are true or false
- (2009) József Bukszár et al. BIOINFORMATICS
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