标题
A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism
作者
关键词
Genome-wide association studies, Drug metabolism, Nicotine, Meta-analysis, Smoking habits, DNA methylation, Genomic signal processing, Enzyme metabolism
出版物
PLoS Genetics
Volume 11, Issue 9, Pages e1005498
出版商
Public Library of Science (PLoS)
发表日期
2015-09-26
DOI
10.1371/journal.pgen.1005498
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces
- (2015) Lynn M. Almli et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration
- (2015) Kristine L P Garcia et al. NEUROPSYCHOPHARMACOLOGY
- Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses
- (2015) Ayşe Demirkan et al. PLoS Genetics
- Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial
- (2015) Caryn Lerman et al. Lancet Respiratory Medicine
- Measures of Substance Consumption Among Substance Users, DSM-IV Abusers, and Those With DSM-IV Dependence Disorders in a Nationally Representative Sample
- (2015) Howard B. Moss et al. Journal of Studies on Alcohol and Drugs
- Downregulation of Notch Signaling Pathway in Late Preterm and Term Placentas from Pregnancies Complicated by Preeclampsia
- (2015) Persefoni Fragkiadaki et al. PLoS One
- Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
- (2014) Martin J. Aryee et al. BIOINFORMATICS
- Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array
- (2014) Haroon Naeem et al. BMC GENOMICS
- Known and Novel Sources of Variability in the Nicotine Metabolite Ratio in a Large Sample of Treatment-Seeking Smokers
- (2014) M. J. Chenoweth et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Forty-year trends in cardiovascular risk factors in Finland
- (2014) K. Borodulin et al. EUROPEAN JOURNAL OF PUBLIC HEALTH
- Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6)
- (2013) Li-Shiun Chen et al. ADDICTION
- Efficacy of interventions to combat tobacco addiction: Cochrane update of 2012 reviews
- (2013) Jamie Hartmann-Boyce et al. ADDICTION
- Haplotype Estimation Using Sequencing Reads
- (2013) Olivier Delaneau et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Regulation of Lung Cancer Metastasis by Klf4-Numb-like Signaling
- (2013) V. Vaira et al. CANCER RESEARCH
- Genetic and Pharmacokinetic Determinants of Response to Transdermal Nicotine in White, Black, and Asian Nonsmokers
- (2013) D A Dempsey et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms
- (2013) A. J. Bloom et al. HUMAN MOLECULAR GENETICS
- Genome-wide association study on detailed profiles of smoking behavior and nicotine dependence in a twin sample
- (2013) A Loukola et al. MOLECULAR PSYCHIATRY
- CYP2A6 slow nicotine metabolism is associated with increased quitting by adolescent smokers
- (2013) Meghan J. Chenoweth et al. Pharmacogenetics and Genomics
- Numblike regulates proliferation, apoptosis, and invasion of lung cancer cell
- (2013) Li Yingjie et al. TUMOR BIOLOGY
- The Finnish Twin Cohort Study: An Update
- (2013) Jaakko Kaprio Twin Research and Human Genetics
- Reproducibility of the Nicotine Metabolite Ratio in Cigarette Smokers
- (2012) G. St.Helen et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Genome-wide association study identifies multiple loci influencing human serum metabolite levels
- (2012) Johannes Kettunen et al. NATURE GENETICS
- Genome-wide efficient mixed-model analysis for association studies
- (2012) Xiang Zhou et al. NATURE GENETICS
- Rutgers Alcohol Problem Index Scores at Age 18 Predict Alcohol Dependence Diagnoses 7 Years Later
- (2011) Danielle M. Dick et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Nicotine Metabolite Ratio Predicts Smoking Topography and Carcinogen Biomarker Level
- (2011) A. A. Strasser et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
- (2011) Jordana T Bell et al. GENOME BIOLOGY
- Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior
- (2010) Thorgeir E Thorgeirsson et al. NATURE GENETICS
- Meta-analysis and imputation refines the association of 15q25 with smoking quantity
- (2010) Jason Z Liu et al. NATURE GENETICS
- Nicotine Addiction
- (2010) Neal L. Benowitz NEW ENGLAND JOURNAL OF MEDICINE
- Genetic origins of the association between verbal ability and alcohol dependence symptoms in young adulthood
- (2010) A. Latvala et al. PSYCHOLOGICAL MEDICINE
- Guidance molecules in lung cancer
- (2010) Patrick Nasarre et al. Cell Adhesion & Migration
- Disentangling molecular relationships with a causal inference test
- (2009) Joshua Millstein et al. BMC GENETICS
- The Neurobiology of Addictive Disorders
- (2009) Stephen Ross et al. CLINICAL NEUROPHARMACOLOGY
- Nicotine Dependence Pharmacogenetics: Role of Genetic Variation in Nicotine-Metabolizing Enzymes
- (2009) Riju Ray et al. JOURNAL OF NEUROGENETICS
- Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
- (2009) Mark S Silverberg et al. NATURE GENETICS
- Genetic and environmental influences on the ratio of 3′hydroxycotinine to cotinine in plasma and urine
- (2009) Gary E. Swan et al. Pharmacogenetics and Genomics
- A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
- (2009) Bryan N. Howie et al. PLoS Genetics
- Pharmacology of Nicotine: Addiction, Smoking-Induced Disease, and Therapeutics
- (2008) Neal L. Benowitz Annual Review of Pharmacology and Toxicology
- Predictors of Smoking Cessation After a Myocardial InfarctionThe Role of Institutional Smoking Cessation Programs in Improving Success
- (2008) Nazeera Dawood ARCHIVES OF INTERNAL MEDICINE
- Toward Personalized Therapy for Smoking Cessation: A Randomized Placebo-controlled Trial of Bupropion
- (2008) F Patterson et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Cohort Profile: The Cardiovascular Risk in Young Finns Study
- (2008) O. T Raitakari et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Aberrant Splicing Caused by Single Nucleotide Polymorphism c.516G>T [Q172H], a Marker of CYP2B6*6, Is Responsible for Decreased Expression and Activity of CYP2B6 in Liver
- (2008) M. H. Hofmann et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: A validation study
- (2008) Robert A. Schnoll et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation