FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2

Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia

(2015) Asuka Hira et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ATR-Mediated Phosphorylation of FANCI Regulates Dormant Origin Firing in Response to Replication Stress

(2015) Yu-Hung Chen et al.   MOLECULAR CELL

Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia

(2015) Kimberly A. Rickman et al.   Cell Reports

The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability

(2014) David Fox et al.   CELL RESEARCH

DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells

(2014) Sehyun Oh et al.   DNA REPAIR

BRCA1 Promotes Unloading of the CMG Helicase from a Stalled DNA Replication Fork

(2014) David T. Long et al.   MOLECULAR CELL

The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

(2014) Eeson Rajendra et al.   MOLECULAR CELL

A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

(2014) Qin Liang et al.   Nature Chemical Biology

Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA

(2014) Simonne Longerich et al.   NUCLEIC ACIDS RESEARCH

The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes

(2014) Qi Zhao et al.   Nature Communications

Biallelic Mutations in BRCA1 Cause a New Fanconi Anemia Subtype

(2014) Sarah L. Sawyer et al.   Cancer Discovery

Modularized Functions of the Fanconi Anemia Core Complex

(2014) Yaling Huang et al.   Cell Reports

Mutations in ERCC4, Encoding the DNA-Repair Endonuclease XPF, Cause Fanconi Anemia

(2013) Massimo Bogliolo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ATR-Dependent Phosphorylation of FANCM at Serine 1045 Is Essential for FANCM Functions

(2013) T. R. Singh et al.   CANCER RESEARCH

RIF1 Counteracts BRCA1-mediated End Resection during DNA Repair

(2013) Lin Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery

(2013) Indrajit Chaudhury et al.   NUCLEIC ACIDS RESEARCH

53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection

(2013) M. Zimmermann et al.   SCIENCE

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

(2013) M. Di Virgilio et al.   SCIENCE

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network

(2012) Zhijiang Yan et al.   MOLECULAR CELL

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase

(2012) Archana Sareen et al.   NUCLEIC ACIDS RESEARCH

Origin, functional role, and clinical impact of Fanconi anemia FANCA mutations

(2011) M. Castella et al.   BLOOD

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

MicroRNA-138 Modulates DNA Damage Response by Repressing Histone H2AX Expression

(2011) Y. Wang et al.   MOLECULAR CANCER RESEARCH

Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR

(2011) Philip M Reaper et al.   Nature Chemical Biology

Mutations of the SLX4 gene in Fanconi anemia

(2011) Yonghwan Kim et al.   NATURE GENETICS

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair

(2010) L. Colnaghi et al.   BLOOD

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

(2009) Jung Min Kim et al.   DEVELOPMENTAL CELL

ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function

(2008) N. B. Collins et al.   BLOOD

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

(2008) J. M. Kim et al.   BLOOD

Mutations to Ku reveal differences in human somatic cell lines

(2008) Kazi R. Fattah et al.   DNA REPAIR

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

(2008) Masamichi Ishiai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

(2008) J B Wilson et al.   ONCOGENE