The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes

Comparative Metabolomics Reveals Endogenous Ligands of DAF-12, a Nuclear Hormone Receptor, Regulating C. elegans Development and Lifespan

(2014) Parag Mahanti et al.   Cell Metabolism

PQM-1 Complements DAF-16 as a Key Transcriptional Regulator of DAF-2-Mediated Development and Longevity

(2013) Ronald G. Tepper et al.   CELL

Discovery of Anthelmintic Drug Targets and Drugs Using Chokepoints in Nematode Metabolic Pathways

(2013) Christina M. Taylor et al.   PLoS Pathogens

Strongyloides stercoralis age-1: A Potential Regulator of Infective Larval Development in a Parasitic Nematode

(2012) Jonathan D. Stoltzfus et al.   PLoS One

A Steroid Receptor-MicroRNA Switch Regulates Life Span in Response to Signals from the Gonad

(2012) Y. Shen et al.   SCIENCE

RNAseq Analysis of the Parasitic Nematode Strongyloides stercoralis Reveals Divergent Regulation of Canonical Dauer Pathways

(2012) Jonathan D. Stoltzfus et al.   PLoS Neglected Tropical Diseases

Fatty Acid Oxidation Is Essential for Egg Production by the Parasitic Flatworm Schistosoma mansoni

(2012) Stanley Ching-Cheng Huang et al.   PLoS Pathogens

New genes that extend Caenorhabditis elegans’ lifespan in response to reproductive signals

(2011) Mark McCormick et al.   AGING CELL

DAF-12 Regulates a Connected Network of Genes to Ensure Robust Developmental Decisions

(2011) Daniel Hochbaum et al.   PLoS Genetics

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

(2009) Eyleen J. O'Rourke et al.   Cell Metabolism

Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans

(2009) J. Thomas Hannich et al.   DEVELOPMENTAL CELL

Synthesis and Activity of Dafachronic Acid Ligands for theC. elegansDAF-12 Nuclear Hormone Receptor

(2009) Kamalesh K. Sharma et al.   MOLECULAR ENDOCRINOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes

(2009) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans

(2009) C. M. Hammell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Starvation Protects Germline Stem Cells and Extends Reproductive Longevity in C. elegans

(2009) G. Angelo et al.   SCIENCE

Nuclear Hormone Receptor Regulation of MicroRNAs Controls Developmental Progression

(2009) Axel Bethke et al.   SCIENCE

Morphogenesis of Strongyloides stercoralis Infective Larvae Requires the DAF-16 Ortholog FKTF-1

(2009) Michelle L. Castelletto et al.   PLoS Pathogens

A Conserved Endocrine Mechanism Controls the Formation of Dauer and Infective Larvae in Nematodes

(2008) Akira Ogawa et al.   CURRENT BIOLOGY

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

(2008) Patrick Narbonne et al.   NATURE