Article
Biochemistry & Molecular Biology
Ling-Li Chen, Jia-Qiang Huang, Yuan-Yuan Wu, Liang-Bing Chen, Shu-Ping Li, Xu Zhang, Sen Wu, Fa-Zheng Ren, Xin-Gen Lei
Summary: Selenoprotein V (SELENOV) knockout in mice resulted in increased body weight and fat mass accumulation, along with decreased energy expenditure. SELENOV interacted with O-GlcNAc transferase (OGT), leading to decreased OGT protein levels and activity, potentially impacting fat metabolism through O-GlcNAcylation regulation.
Article
Nutrition & Dietetics
Shing-Hwa Liu, Yu-Xuan Chen, Huei-Ping Tzeng, Meng-Tsan Chiang
Summary: Low-carbohydrate and high-fat diets can cause lipid metabolism disturbance and fat accumulation, but fish oil supplementation can improve these adverse effects.
Article
Nutrition & Dietetics
Tengteng Ji, Bing Fang, Fang Wu, Yaqiong Liu, Le Cheng, Yixuan Li, Ran Wang, Longjiao Zhu
Summary: The number of obese people is increasing worldwide due to high-fat diets causing excess energy intake. A 12-week dietary intervention study on high-fat diet-induced obese mice showed that changing the diet significantly reduced weight gain and subcutaneous adipose tissue weight. Diet change also affected lipolysis, lipogenesis, and the proportion of adipocyte stem cells in different fat tissues.
Article
Nutrition & Dietetics
Jessica Petrine Castro Pereira, Erika Aparecida Oliveira, Fernanda Aparecida Castro Pereira, Josilene Nascimento Seixas, Camila Souza de Oliveira Guimaraes, Bruno Del Bianco Borges
Summary: Flaxseed and mulberry extracts have high antioxidant activity and contain a large amount of phenolic compounds. The use of these extracts can alleviate the negative effects caused by low endogenous estrogen action, such as reducing weight gain and improving vaginal epithelial cells.
Article
Nutrition & Dietetics
Aleksandra Pieta, Barbara Fraczek, Magdalena Wiecek, Paulina Mazur-Kurach
Summary: The study aimed to examine the effects of the Paleo diet on body composition and blood markers. The findings showed that compared to the control group, the Paleo diet resulted in lower body weight and higher blood concentration of adiponectin, but had no significant impact on other body composition and biochemical markers.
Article
Endocrinology & Metabolism
Christian A. Unger, Ahmed K. Aladhami, Marion C. Hope, William E. Cotham, Kendall W. Nettles, Deborah J. Clegg, Kandy T. Velazquez, Reilly T. Enos
Summary: This study indicates that enhanced skeletal muscle aromatase activity in male mice can mitigate the negative effects of a high-fat diet on obesity-associated metabolic impairments. Skeletal muscle estrogen can improve metabolic and inflammatory outcomes while promoting skeletal muscle hypertrophy, thus improving metabolic abnormalities and inflammation caused by a high-fat diet.
Article
Public, Environmental & Occupational Health
Piet A. van den Brandt, Regina G. Ziegler, Molin Wang, Tao Hou, Ruifeng Li, Hans-Olov Adami, Claudia Agnoli, Leslie Bernstein, Julie E. Buring, Yu Chen, Avonne E. Connor, A. Heather Eliassen, Jeanine M. Genkinger, Gretchen Gierach, Graham G. Giles, Gary G. Goodman, Niclas Hakansson, Vittorio Krogh, Loic Le Marchand, I-Min Lee, Linda M. Liao, M. Elena Martinez, Anthony B. Miller, Roger L. Milne, Marian L. Neuhouser, Alpa V. Patel, Anna Prizment, Kim Robien, Thomas E. Rohan, Norie Sawada, Leo J. Schouten, Rashmi Sinha, Rachael Z. Stolzenberg-Solomon, Lauren R. Teras, Shoichiro Tsugane, Kala Visvanathan, Elisabete Weiderpass, Kami K. White, Walter C. Willett, Alicja Wolk, Anne Zeleniuch-Jacquotte, Stephanie A. Smith-Warner
Summary: The associations between anthropometric factors and breast cancer risk vary inconsistently by estrogen and progesterone receptor status. Height, body mass index, adult weight gain show different strengths and directions of associations with breast cancer risk.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Food Science & Technology
Michal Wrzosek, Jakub Wozniak, Dariusz Wlodarek
Summary: The study assessed the impact of low-fat, high-carb (LFHC) and low-carb, high-fat (LCHF) diets on body composition of healthy weight men doing strength sports for 12 weeks, with results showing similar effects on body composition changes between the two diets.
FOOD SCIENCE & NUTRITION
(2021)
Review
Nutrition & Dietetics
Carlos Ruiz-Castellano, Sergio Espinar, Carlos Contreras, Fernando Mata, Alan A. Aragon, Jose Miguel Martinez-Sanz
Summary: This study focuses on the dietary-nutritional strategies for fat loss in resistance-trained athletes, emphasizing the goal of maximizing fat-free mass retention through proper caloric and protein intake. Additionally, carbohydrate intake and supplements such as caffeine and creatine monohydrate can also play a role in enhancing training performance in athletes.
Article
Nutrition & Dietetics
Nadine B. Wachsmuth, Felix Aberer, Sandra Haupt, Janis R. Schierbauer, Rebecca T. Zimmer, Max L. Eckstein, Beate Zunner, Walter Schmidt, Tobias Niedrist, Harald Sourij, Othmar Moser
Summary: This study investigated the effects of short-term high-carbohydrate/low-fat and low-carbohydrate diets on physical performance and body composition. The results showed that the high-carbohydrate/low-fat diet improved physical performance and led to a decrease in body weight and fat mass, but had no effect on lean body mass and skeletal muscle mass.
Article
Biochemistry & Molecular Biology
Junting Xie, Xiaoning Hou, Wanshi He, Jie Xiao, Yong Cao, Xiaojuan Liu
Summary: Although the specific action site and signal pathway of astaxanthin in weight loss remain unclear, this study used Caenorhabditis elegans to shed light on its efficacy and specific action sites. The supplementation of 60 μM astaxanthin significantly reduced fat deposition and triglyceride levels and prevented obesity caused by excessive energy accumulation. These effects were induced by sbp-1/mdt-15 and insulin/insulin-like growth factor pathways, and co-regulated the down-regulation of specific sites fat-6 and fat-7.
Article
Endocrinology & Metabolism
Wuling Zhong, Hui Wang, Yale Yang, Yali Zhang, Hejin Lai, Yalan Cheng, Huimin Yu, Ning Feng, Rui Huang, Shen Liu, Sheng Yang, Tongyang Hao, Baoyu Zhang, Hao Ying, Fang Zhang, Feifan Guo, Qiwei Zhai
Summary: Post-dieting fat mass increase is caused by enhanced intestinal lipid absorption, which is influenced by the increase in intestinal Lactobacillus. Inhibiting the growth of intestinal Lactobacillus through a high-protein diet or antibiotics can prevent fat accumulation.
Article
Food Science & Technology
Xiaorong Wang, Liying Zhu, Xiaoqiong Li, Xin Wang, Ruirong Hao, Jinjun Li
Summary: This study investigated the effects of HFCS on body fat and intestinal microbiota in mice, finding that HFCS increased body fat and altered the microbial composition. The Christensenellaceae R-7 group showed a negative correlation with various fat measures.
NPJ SCIENCE OF FOOD
(2022)
Article
Nutrition & Dietetics
Ahreum Lee, Eugene Koh, Dalnim Kim, Namkyu Lee, Soo Min Cho, Young Joo Lee, Ik-Hyun Cho, Hyun-Jeong Yang
Summary: This study examined the effects of DT sap on body weight and muscle metabolism in mice. The results showed that DT sap inhibited weight gain and increased muscle metabolism. It was found that DT sap activated the AMPK signaling pathway and estrogen alpha receptor, which may be related to the observed muscle metabolism and weight changes.
Article
Multidisciplinary Sciences
Kalpana D. D. Acharya, Madeline Graham, Harshini Raman, Abigail E. R. Parakoyi, Alexis Corcoran, Merzu Belete, Bharath Ramaswamy, Shashikant Koul, Ishneet Sachar, Kevin Derendorf, Jeremy B. B. Wilmer, Srikanth Gottipati, Marc J. J. Tetel
Summary: Decreased estrogens during menopause increase the risk of anxiety, depression, type 2 diabetes, and obesity. Depleting estrogens and having a high-fat diet in rodents also lead to anxiety and adiposity. The interaction between estrogens, diet, anxiety, and metabolism is poorly understood, but evidence suggests that gut microbiota play a role.
SCIENTIFIC REPORTS
(2023)