AMP-Activated Protein Kinase Deficiency Rescues Paraquat-Induced Cardiac Contractile Dysfunction Through an Autophagy-Dependent Mechanism
出版年份 2014 全文链接
标题
AMP-Activated Protein Kinase Deficiency Rescues Paraquat-Induced Cardiac Contractile Dysfunction Through an Autophagy-Dependent Mechanism
作者
关键词
-
出版物
TOXICOLOGICAL SCIENCES
Volume 142, Issue 1, Pages 6-20
出版商
Oxford University Press (OUP)
发表日期
2014-08-05
DOI
10.1093/toxsci/kfu158
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer
- (2014) Claudia Fumarola et al. BIOCHEMICAL PHARMACOLOGY
- Mammalian Target of Rapamycin Signaling in Cardiac Physiology and Disease
- (2014) Sebastiano Sciarretta et al. CIRCULATION RESEARCH
- Inhibition of Mammalian Target of Rapamycin With Rapamycin Reverses Hypertrophic Cardiomyopathy in Mice With Cardiomyocyte-Specific Knockout of PTEN
- (2014) Xihui Xu et al. HYPERTENSION
- How Parkinsonian Toxins Dysregulate the Autophagy Machinery
- (2013) Ruben Dagda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Rapalogs and mTOR inhibitors as anti-aging therapeutics
- (2013) Dudley W. Lamming et al. JOURNAL OF CLINICAL INVESTIGATION
- Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1
- (2013) D. N. Tripathi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impairment of Atg5-Dependent Autophagic Flux Promotes Paraquat- and MPP+-Induced Apoptosis But Not Rotenone or 6-Hydroxydopamine Toxicity
- (2013) Aracely Garcia-Garcia et al. TOXICOLOGICAL SCIENCES
- Macrophage Migration Inhibitory Factor Deficiency Augments Doxorubicin‐Induced Cardiomyopathy
- (2013) Xihui Xu et al. Journal of the American Heart Association
- Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation
- (2012) Rui Guo et al. CARDIOVASCULAR RESEARCH
- Paraquat, but Not Maneb, Induces Synucleinopathy and Tauopathy in Striata of Mice through Inhibition of Proteasomal and Autophagic Pathways
- (2012) Jonathan Wills et al. PLoS One
- Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation
- (2012) Xihui Xu et al. Journal of Molecular Cell Biology
- Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop
- (2011) Antje S. Löffler et al. Autophagy
- The serine/threonine kinase ULK1 is a target of multiple phosphorylation events
- (2011) Markus Bach et al. BIOCHEMICAL JOURNAL
- Tuning flux: autophagy as a target of heart disease therapy
- (2011) Min Xie et al. CURRENT OPINION IN CARDIOLOGY
- Autophagy as a therapeutic target in cardiovascular disease
- (2011) Andriy Nemchenko et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Cardiac-specific overexpression of catalase attenuates paraquat-induced myocardial geometric and contractile alteration: Role of ER stress
- (2010) We Ge et al. FREE RADICAL BIOLOGY AND MEDICINE
- Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: Modulation by the Nrf2/Trx axis
- (2010) Mireia Niso-Santano et al. FREE RADICAL BIOLOGY AND MEDICINE
- Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction
- (2010) Subat Turdi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The Association of AMPK with ULK1 Regulates Autophagy
- (2010) Jong Woo Lee et al. PLoS One
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- ASK1 Overexpression Accelerates Paraquat-Induced Autophagy via Endoplasmic Reticulum Stress
- (2010) Mireia Niso-Santano et al. TOXICOLOGICAL SCIENCES
- The Role of NADPH Oxidase 1–Derived Reactive Oxygen Species in Paraquat-Mediated Dopaminergic Cell Death
- (2009) Ana Clara Cristóvão et al. ANTIOXIDANTS & REDOX SIGNALING
- Markers of Autophagy Are Downregulated in Failing Human Heart After Mechanical Unloading
- (2009) C. Kassiotis et al. CIRCULATION
- Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts
- (2009) Jun Ren et al. CRITICAL CARE MEDICINE
- mTOR and cancer: many loops in one pathway
- (2009) Alejo Efeyan et al. CURRENT OPINION IN CELL BIOLOGY
- ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
- (2009) Ian G. Ganley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aldehyde dehydrogenase-2 transgene ameliorates chronic alcohol ingestion-induced apoptosis in cerebral cortex
- (2009) Jun Ren et al. TOXICOLOGY LETTERS
- LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
- (2008) Hua Yuan et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Toxicokinetics and toxicodynamics of paraquat accumulation in mouse brain
- (2008) Kavita Prasad et al. EXPERIMENTAL NEUROLOGY
- Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism
- (2008) E. Y. W. Chan et al. MOLECULAR AND CELLULAR BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started