Zinc Finger Nuclease–Mediated Knockout of AHR or ARNT in Human Breast Cancer Cells Abolishes Basal and Ligand-Dependent Regulation of CYP1B1 and Differentially Affects Estrogen Receptor α Transactivation

Estrogen receptor α can selectively repress dioxin receptor-mediated gene expression by targeting DNA methylation

(2013) Maud Marques et al.   NUCLEIC ACIDS RESEARCH

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice

(2013) Joshua A. Harrill et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Distinct Roles for Aryl Hydrocarbon Receptor Nuclear Translocator and Ah Receptor in Estrogen-Mediated Signaling in Human Cancer Cell Lines

(2012) Mark P. Labrecque et al.   PLoS One

ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

(2011) Thomas J Cradick et al.   BMC BIOINFORMATICS

Move over ZFNs

(2011)   NATURE BIOTECHNOLOGY

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B

(2011) C. L. Partch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of aryl hydrocarbon receptor-dependent transcription by resveratrol or kaempferol is independent of estrogen receptor α expression in human breast cancer cells

(2010) Laura MacPherson et al.   CANCER LETTERS

Functional analysis of six human aryl hydrocarbon receptor variants in human breast cancer and mouse hepatoma cell lines

(2010) Trine Celius et al.   TOXICOLOGY

The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy

(2009) Shu Zhang et al.   ENDOCRINE-RELATED CANCER

Activation of the Aryl-Hydrocarbon Receptor Inhibits Invasive and Metastatic Features of Human Breast Cancer Cells and Promotes Breast Cancer Cell Differentiation

(2009) Julie M. Hall et al.   MOLECULAR ENDOCRINOLOGY

Dioxin Increases the Interaction Between Aryl Hydrocarbon Receptor and Estrogen Receptor Alpha at Human Promoters

(2009) Shaimaa Ahmed et al.   TOXICOLOGICAL SCIENCES

Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

(2008) Maureen K. Bunger et al.   TOXICOLOGICAL SCIENCES