Comparison of Hepatic Transcription Profiles of Locked Ribonucleic Acid Antisense Oligonucleotides: Evidence of Distinct Pathways Contributing to Non-target Mediated Toxicity in Mice

Assessing the translatability of In vivo cardiotoxicity mechanisms to In vitro models using causal reasoning

(2013) Ahmed E Enayetallah et al.   BMC Pharmacology & Toxicology

Causal reasoning on biological networks: interpreting transcriptional changes

(2012) Leonid Chindelevitch et al.   BIOINFORMATICS

Myosin 1E coordinates actin assembly and cargo trafficking during clathrin-mediated endocytosis

(2012) Jackie Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

The long march of antisense

(2011) Dan Jones   NATURE REVIEWS DRUG DISCOVERY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes

(2011) Erich Koller et al.   NUCLEIC ACIDS RESEARCH

Modeling the Mechanism of Action of a DGAT1 Inhibitor Using a Causal Reasoning Platform

(2011) Ahmed E. Enayetallah et al.   PLoS One

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

(2010) Ellen Marie Straarup et al.   NUCLEIC ACIDS RESEARCH

Ethanol selectively impairs clathrin-mediated internalization in polarized hepatic cells

(2009) David J. Fernandez et al.   BIOCHEMICAL PHARMACOLOGY

The Role of Hypoxia in 2-Butoxyethanol–Induced Hemangiosarcoma

(2009) Daphna Laifenfeld et al.   TOXICOLOGICAL SCIENCES

Impaired receptor-mediated endocytosis: Its role in alcohol-induced apoptosis

(2008) Carol A Casey et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY