Utility of Rat Liver S9 Fractions to Study Skin-Sensitizing Prohaptens in a Modified KeratinoSens Assay

Elucidation of Xenobiotic Metabolism Pathways in Human Skin and Human Skin Models by Proteomic Profiling

(2012) Sven van Eijl et al.   PLoS One

Langerhans Cells Facilitate Epithelial DNA Damage and Squamous Cell Carcinoma

(2012) B. G. Modi et al.   SCIENCE

The Direct Peptide Reactivity Assay: Selectivity of Chemical Respiratory Allergens

(2012) Jon F. Lalko et al.   TOXICOLOGICAL SCIENCES

Evaluating the sensitization potential of surfactants: Integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach

(2011) Nicholas Ball et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The Incorporation of Lysine into the Peroxidase Peptide Reactivity Assay for Skin Sensitization Assessments

(2011) John A. Troutman et al.   TOXICOLOGICAL SCIENCES

Cross Talk between Keratinocytes and Dendritic Cells: Impact on the Prediction of Sensitization

(2011) Jenny Hennen et al.   TOXICOLOGICAL SCIENCES

Discrimination of haptens from prohaptens using the metabolically deficient Cprlow/low mouse

(2011) Itai Chipinda et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models

(2011) Christine Jäckh et al.   TOXICOLOGY IN VITRO

Contact allergy to fragrances: current patch test results (2005-2008) from the Information Network of Departments of Dermatology*

(2010) Wolfgang Uter et al.   CONTACT DERMATITIS

A pre-validation transferability study of the GreenScreen HC GADD45a-GFP assay with a metabolic activation system (S9)

(2010) Nicholas Billinton et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Use of the human monocytic leukemia THP-1 cell line and co-incubation with microsomes to identify and differentiate hapten and prohapten sensitizers

(2010) Itai Chipinda et al.   TOXICOLOGY

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro

(2010) Roger Emter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: Results of a ring-study in five laboratories

(2010) Natsch Andreas et al.   TOXICOLOGY IN VITRO

Cutaneous Metabolic Activation of Carvoxime, a Self-Activating, Skin-Sensitizing Prohapten

(2009) Hagen Ott et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin™ and full thickness model from Episkin™

(2009) Van Luu-The et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Nrf2-Keap1-ARE Toxicity Pathway as a Cellular Sensor for Skin Sensitizers—Functional Relevance and a Hypothesis on Innate Reactions to Skin Sensitizers

(2009) Andreas Natsch   TOXICOLOGICAL SCIENCES

Investigation of Peptide Reactivity of Pro-hapten Skin Sensitizers Using a Peroxidase-Peroxide Oxidation System

(2009) G. Frank Gerberick et al.   TOXICOLOGICAL SCIENCES

Evaluation of cytochrome P450 1 (CYP1) and N-acetyltransferase 1 (NAT1) activities in HaCaT cells: Implications for the development of in vitro techniques for predictive testing of contact sensitizers

(2009) Jutta Bonifas et al.   TOXICOLOGY IN VITRO

LC-MS–Based Characterization of the Peptide Reactivity of Chemicals to Improve the In Vitro Prediction of the Skin Sensitization Potential

(2008) Andreas Natsch et al.   TOXICOLOGICAL SCIENCES

Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergens

(2008) Lina Hagvall et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Allergic Contact Dermatitis––Formation, Structural Requirements, and Reactivity of Skin Sensitizers

(2007) Ann-Therese Karlberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY