Efficient Monitoring of In Vivo Pig-a Gene Mutation and Chromosomal Damage: Summary of 7 Published Studies and Results From 11 New Reference Compounds

Integration of Pig-a, micronucleus, chromosome aberration, and comet assay endpoints in a 28-day rodent toxicity study with 4-nitroquinoline-1-oxide

(2011) Leon F. Stankowski et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Report on stage III Pig-a mutation assays using N-ethyl-N-nitrosourea - comparison with other in vivo genotoxicity endpoints

(2011) Zoryana Cammerer et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies

(2011) Jing Shi et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

International Pig-a gene mutation assay trial (Stage III): Results with N-methyl-N-nitrosourea

(2011) Anthony M. Lynch et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Manifestation and persistence of Pig-a mutant red blood cells in C57BL/6 mice following single and split doses of N-ethyl-N-nitrosourea

(2011) Javed A. Bhalli et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Report on stage III Pig-a mutation assays using benzo[a]pyrene

(2011) Javed A. Bhalli et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes

(2011) Stephen D. Dertinger et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories

(2011) Stephen D. Dertinger et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

When pigs fly: Immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis

(2011) Stephen D. Dertinger et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The in vivo pig-a gene mutation assay, a potential tool for regulatory safety assessment

(2010) Vasily N. Dobrovolsky et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol

(2010) Leslie Recio et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

(2010) Andreas Rothfuss et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Compilation and use of genetic toxicity historical control data

(2010) Makoto Hayashi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Improvement of in vivo genotoxicity assessment: Combination of acute tests and integration into standard toxicity testing

(2010) Andreas Rothfuss et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Integration of Mutation and Chromosomal Damage Endpoints into 28-Day Repeat Dose Toxicology Studies

(2010) Stephen D. Dertinger et al.   TOXICOLOGICAL SCIENCES

Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea

(2009) Daishiro Miura et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities—Report from an ECVAM workshop

(2009) Stefan Pfuhler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The use of PIG-A as a sentinel gene for the study of the somatic mutation rate and of mutagenic agents in vivo

(2009) Benedetta Peruzzi et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens

(2009) Souk Phonethepswath et al.   TOXICOLOGICAL SCIENCES

In vivo mutation assay based on the endogenousPig-a locus

(2008) Steven M. Bryce et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Development of an in vivo gene mutation assay using the endogenousPig-Agene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat

(2008) Daishiro Miura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Erythrocyte-based Pig-a gene mutation assay: Demonstration of cross-species potential

(2008) Souk Phonethepswath et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Evaluation of Macaca mulatta as a model for genotoxicity studies

(2008) Vasily N. Dobrovolsky et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS