In Vivo Genotoxicity of Methyleugenol in gpt Delta Transgenic Rats Following Medium-Term Exposure

Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats

(2012) Yuta Suzuki et al.   ARCHIVES OF TOXICOLOGY

Identification of human and murine sulfotransferases able to activate hydroxylated metabolites of methyleugenol to mutagens in Salmonella typhimurium and detection of associated DNA adducts using UPLC-MS/MS methods

(2012) K. Herrmann et al.   MUTAGENESIS

Metabolism of Methyleugenol in Liver Microsomes and Primary Hepatocytes: Pattern of Metabolites, Cytotoxicity, and DNA-Adduct Formation

(2012) Alexander T. Cartus et al.   TOXICOLOGICAL SCIENCES

Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat

(2012) Ala' A.A. Al-Subeihi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Physiologically Based Biokinetic (PBBK) Model for Safrole Bioactivation and Detoxification in Rats

(2011) E. Martati et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Detection and Quantification of Specific DNA Adducts by Liquid Chromatography−Tandem Mass Spectrometry in the Livers of Rats Given Estragole at the Carcinogenic Dose

(2011) Yuji Ishii et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Methyleugenol Genotoxicity in the Fischer 344 Rat Using the Comet Assay and Pathway-Focused Gene Expression Profiling

(2011) Wei Ding et al.   TOXICOLOGICAL SCIENCES

Comprehensive toxicity study of safrole using a medium-term animal model with gpt delta rats

(2011) M. Jin et al.   TOXICOLOGY

Integration of In Vivo Genotoxicity and Short-term Carcinogenicity Assays Using F344 gpt Delta Transgenic Rats: In Vivo Mutagenicity of 2,4-Diaminotoluene and 2,6-Diaminotoluene Structural Isomers

(2009) Naomi Toyoda-Hokaiwado et al.   TOXICOLOGICAL SCIENCES

Possible participation of oxidative stress in causation of cell proliferation and in vivo mutagenicity in kidneys of gpt delta rats treated with potassium bromate

(2008) Takashi Umemura et al.   TOXICOLOGY