Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption

Evaluation of BEH C18, BEH HILIC, and HSS T3 (C18) Column Chemistries for the UPLC-MS-MS Analysis of Glutathione, Glutathione Disulfide, and Ophthalmic Acid in Mouse Liver and Human Plasma

(2013) L.-S. New et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity

(2010) Jingbo Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver

(2010) Neil R. Kitteringham et al.   Journal of Proteomics

Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap1

(2010) K. Taguchi et al.   MOLECULAR AND CELLULAR BIOLOGY

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Induction of Heme Oxygenase-1, Biliverdin Reductase and H-Ferritin in Lung Macrophage in Smokers with Primary Spontaneous Pneumothorax: Role of HIF-1α

(2010) Delphine Goven et al.   PLoS One

Deletion ofKeap1in the Lung Attenuates Acute Cigarette Smoke–Induced Oxidative Stress and Inflammation

(2009) David J. Blake et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes

(2009) Scott A. Reisman et al.   BIOCHEMICAL PHARMACOLOGY

Biochemical effects of SIRT1 activators

(2009) Joseph A. Baur   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia

(2009) Chenhui Yang et al.   BRAIN RESEARCH

Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide

(2009) Soona Shin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Identification and characterization of an Nrf2-mediated ARE upstream of the rat glutamate cysteine ligase catalytic subunit gene (GCLC)

(2009) Muyao Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Kaempferol Suppresses Cisplatin-Induced Apoptosis Via Inductions of Heme Oxygenase-1 and Glutamate-Cysteine Ligase Catalytic Subunit in HEI-OC1 cells

(2009) Shang Shang Gao et al.   PHARMACEUTICAL RESEARCH

Increased Nrf2 Activation in Livers from Keap1-Knockdown Mice Increases Expression of Cytoprotective Genes that Detoxify Electrophiles more than those that Detoxify Reactive Oxygen Species

(2009) Scott A. Reisman et al.   TOXICOLOGICAL SCIENCES

ANIT-Induced Intrahepatic Cholestasis Alters Hepatobiliary Transporter Expression via Nrf2-Dependent and Independent Signaling

(2009) Yuji Tanaka et al.   TOXICOLOGICAL SCIENCES

Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages

(2009) Courtney G. Woods et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes

(2009) Scott A. Reisman et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice

(2008) Kosuke Okada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Resveratrol and 4-hydroxynonenal act in concert to increase glutamate cysteine ligase expression and glutathione in human bronchial epithelial cells

(2008) Hongqiao Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Curcumin and cancer: An “old-age” disease with an “age-old” solution

(2008) Preetha Anand et al.   CANCER LETTERS

The Nrf2 Activator Oltipraz Also Activates the Constitutive Androstane Receptor

(2008) M. D. Merrell et al.   DRUG METABOLISM AND DISPOSITION

Nuclear Factor-Eythroid 2–Related Factor 2 Prevents Alcohol-Induced Fulminant Liver Injury

(2008) Jutta Lamlé et al.   GASTROENTEROLOGY

NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet

(2008) Y. Tanaka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS