Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity

Definition of the Landscape of Promoter DNA Hypomethylation in Liver Cancer

(2011) B. Stefanska et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies

(2010) M. Teresa Donato et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Integrating individual functional moieties of CXCL10 and CXCL11 into a novel chimeric chemokine leads to synergistic antitumor effects: a strategy for chemokine-based multi-target-directed cancer therapy

(2010) Ping Wang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Characterization of E2F3a function in HepG2 liver cancer cells

(2010) Wei Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cell cycle and cell death in disease: past, present and future

(2010) B. Zhivotovsky et al.   JOURNAL OF INTERNAL MEDICINE

Evaluation of Possible Carcinogenic Risk to Humans Based on Liver Tumors in Rodent Assays

(2010) Samuel M. Cohen   TOXICOLOGIC PATHOLOGY

Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification

(2010) Danyel G. J. Jennen et al.   TOXICOLOGICAL SCIENCES

SAGE analysis highlights the importance of p53csv, ddx5, mapkapk2 and ranbp2 to multiple myeloma tumorigenesis

(2009) Roberta S. Felix et al.   CANCER LETTERS

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

Hepatocyte-like cells derived from human embryonic stem cells specifically via definitive endoderm and a progenitor stage

(2009) Gabriella Brolén et al.   JOURNAL OF BIOTECHNOLOGY

Human embryonic stem cell technologies and drug discovery

(2009) Janne Jensen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

(2009) Lya G. Hernández et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Chemical regulators have overreached

(2009) Thomas Hartung et al.   NATURE

Discrimination for Genotoxic and Nongenotoxic Carcinogens by Gene Expression Profiling in Primary Mouse Hepatocytes Improves with Exposure Time

(2009) Karen Mathijs et al.   TOXICOLOGICAL SCIENCES

Characterization and Interlaboratory Comparison of a Gene Expression Signature for Differentiating Genotoxic Mechanisms

(2009) Heidrun Ellinger-Ziegelbauer et al.   TOXICOLOGICAL SCIENCES

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

Strategies to In Vitro Assessment of Major Human CYP Enzyme Activities by Using Liquid Chromatography Tandem Mass Spectrometry

(2008) A. Lahoz et al.   CURRENT DRUG METABOLISM

The carcinoGENOMICS project: Critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

(2008) M VINKEN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Inferring Pathway Activity toward Precise Disease Classification

(2008) Eunjung Lee et al.   PLoS Computational Biology

Mechanistic Evaluation of PPARα-Mediated Hepatocarcinogenesis: Are We There Yet?

(2007) Jeffrey M. Peters   TOXICOLOGICAL SCIENCES

Value of Rodent Carcinogenesis Bioassays

(2007) Jerrold M. Ward   TOXICOLOGY AND APPLIED PHARMACOLOGY