Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium

Oxidative Stress and Chromium(VI) Carcinogenesis

(2012) Hua Yao et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis

(2010) Nicole M. Gatto et al.   Cancer Epidemiology

Chromium genotoxicity: A double-edged sword

(2010) Kristen P. Nickens et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Carcinogenic mode of action of folpet in mice and evaluation of its relevance to humans

(2010) Samuel M. Cohen et al.   CRITICAL REVIEWS IN TOXICOLOGY

Genetic toxicology of folpet and captan

(2010) Gail T. Arce et al.   CRITICAL REVIEWS IN TOXICOLOGY

A quantitative assessment of the carcinogenicity of hexavalent chromium by the oral route and its relevance to human exposure

(2010) Alan H. Stern   ENVIRONMENTAL RESEARCH

Measurement of tumor-associated mutations in the nasal mucosa of rats exposed to varying doses of formaldehyde

(2010) Fanxue Meng et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Exposure to Hexavalent Chromium Resulted in Significantly Higher Tissue Chromium Burden Compared With Trivalent Chromium Following Similar Oral Doses to Male F344/N Rats and Female B6C3F1 Mice

(2010) Bradley J. Collins et al.   TOXICOLOGICAL SCIENCES

Histopathologic Features and Microsatellite Instability of Cancers of the Papilla of Vater and Their Precursor Lesions

(2009) Petra Ruemmele et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Genetic Susceptibility to Gastrointestinal Cancer: Minireview of the Genomewide Studies

(2009) Masayoshi Tokuoka et al.   ANNALS OF SURGICAL ONCOLOGY

Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens

(2009) Alan R. Boobis et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The Key Events Dose-Response Framework: A Cross-Disciplinary Mode-of-Action Based Approach to Examining Dose-Response and Thresholds

(2009) Elizabeth Julien* et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization

(2009) Annie M. Jarabek et al.   CRITICAL REVIEWS IN TOXICOLOGY

Epigenetics and environmental chemicals

(2009) Andrea Baccarelli et al.   CURRENT OPINION IN PEDIATRICS

Lung Inflammation, Injury, and Proliferative Response after Repetitive Particulate Hexavalent Chromium Exposure

(2009) Laura M. Beaver et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cancer Mortality in a Chinese Population Exposed to Hexavalent Chromium in Drinking Water

(2009) James J. Beaumont et al.   EPIDEMIOLOGY

Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years

(2009) M.D. Stout et al.   FOOD AND CHEMICAL TOXICOLOGY

Molecular physiology and genetics of Na+-independent SLC4 anion exchangers

(2009) S. L. Alper   JOURNAL OF EXPERIMENTAL BIOLOGY

Cancer Mortality in Chinese Populations Surrounding an Alloy Plant with Chromium Smelting Operations

(2009) Brent D. Kerger et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability

(2009) C.F.D. Rodrigues et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Nitrative and Oxidative Stress in Toxicology and Disease

(2009) Ruth A. Roberts et al.   TOXICOLOGICAL SCIENCES

Modulation of histone methylation and MLH1 gene silencing by hexavalent chromium

(2009) Hong Sun et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Macrophage migration inhibitory factor regulatesproliferation of gastric cancer cellsvia the PI3K/Akt pathway

(2009) Guo-Qing Li et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Oral administration of potassium dichromate inhibits brush border membrane enzymes and alters anti-oxidant status of rat intestine

(2008) N. A. Arivarasu et al.   ARCHIVES OF TOXICOLOGY

Excision repair is required for genotoxin-induced mutagenesis in mammalian cells

(2008) Bradford Brooks et al.   CARCINOGENESIS

Hexavalent Chromium Is Carcinogenic to F344/N Rats and B6C3F1 Mice after Chronic Oral Exposure

(2008) Matthew D. Stout et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Genomic and Epigenetic Instability in Colorectal Cancer Pathogenesis

(2008) William M. Grady et al.   GASTROENTEROLOGY

The comet assay: topical issues

(2008) A. R. Collins et al.   MUTAGENESIS

Application of mode-of-action considerations in human cancer risk assessment

(2008) Gary M. Williams   TOXICOLOGY LETTERS

Defining ‘chromosomal instability’

(2008) Jochen B. Geigl et al.   TRENDS IN GENETICS

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Lack of genotoxic effects in hematopoietic and gastrointestinal cells of mice receiving chromium(VI) with the drinking water

(2007) S DEFLORA et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH