Formaldehyde: Integrating Dosimetry, Cytotoxicity, and Genomics to Understand Dose-Dependent Transitions for an Endogenous Compound

Basal Dynamics of p53 Reveal Transcriptionally Attenuated Pulses in Cycling Cells

(2010) Alexander Loewer et al.   CELL

Multi-Dose-Route, Multi-Species Pharmacokinetic Models for Manganese and Their Use in Risk Assessment

(2010) Melvin E. Andersen et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Computational Systems Biology and Dose-Response Modeling in Relation to New Directions in Toxicity Testing

(2010) Qiang Zhang et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Virtual Tissues in Toxicology

(2010) Imran Shah et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Toxicity Testing in the 21st Century: A Vision and a Strategy

(2010) Daniel Krewski et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Fourier analysis and systems identification of the p53 feedback loop

(2010) N. Geva-Zatorsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coexistence of Quiescent and Active Adult Stem Cells in Mammals

(2010) L. Li et al.   SCIENCE

Distribution of DNA Adducts Caused by Inhaled Formaldehyde Is Consistent with Induction of Nasal Carcinoma but Not Leukemia

(2010) Kun Lu et al.   TOXICOLOGICAL SCIENCES

The Vision of Toxicity Testing in the 21st Century: Moving from Discussion to Action

(2010) Melvin E. Andersen et al.   TOXICOLOGICAL SCIENCES

Stem cells and cancer in the aerodigestive tract

(2009) Malcolm R. Alison   EUROPEAN JOURNAL OF CANCER

Risk assessment of genotoxic mutagens with thresholds: A brief introduction

(2009) M. Kirsch-Volders et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose–response relationships, exemplified for mutagenicity data

(2009) Werner K. Lutz et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Distinct mechanisms act in concert to mediate cell cycle arrest

(2009) Jared E. Toettcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Stress Response Pathway System as a Sentinel Ensemble in Toxicological Screening

(2009) Steven O. Simmons et al.   TOXICOLOGICAL SCIENCES

Microarray analysis of gene expression in rat alveolar epithelial cells exposed to fractionated organic extracts of diesel exhaust particles

(2009) Seiichi Omura et al.   TOXICOLOGY

Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs

(2008) Anju Singh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endogenous lung stem cells and contribution to disease

(2008) JC Snyder et al.   JOURNAL OF PATHOLOGY

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

(2008) M. Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage

(2008) Eric Batchelor et al.   MOLECULAR CELL

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Genomic Signatures and Dose-Dependent Transitions in Nasal Epithelial Responses to Inhaled Formaldehyde in the Rat

(2008) Melvin E. Andersen et al.   TOXICOLOGICAL SCIENCES

Toxicity Testing in the 21st Century: Bringing the Vision to Life

(2008) Melvin E. Andersen et al.   TOXICOLOGICAL SCIENCES

Biomarkers in Toxicology and Risk Assessment: Informing Critical Dose–Response Relationships

(2007) James A. Swenberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY