What Makes a Protein Sequence a Prion?

Increasing Prion Propensity by Hydrophobic Insertion

(2014) Aaron C. Gonzalez Nelson et al.   PLoS One

Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains

(2013) Vladimir Espinosa Angarica et al.   BMC GENOMICS

Aggregation Prone Regions and Gatekeeping Residues in Protein Sequences

(2013) Jacinte Beerten et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Interactions between Aβ and Mutated Tau Lead to Polymorphism and Induce Aggregation of Aβ-Mutated Tau Oligomeric Complexes

(2013) Yoav Raz et al.   PLoS One

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

(2012) Oliver D. King et al.   BRAIN RESEARCH

Amyloid-Like Fibril Formation by PolyQ Proteins: A Critical Balance between the PolyQ Length and the Constraints Imposed by the Host Protein

(2012) Natacha Scarafone et al.   PLoS One

De novo design of synthetic prion domains

(2012) J. A. Toombs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purified and synthetic Alzheimer's amyloid beta (A ) prions

(2012) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation via Polymorphic States

(2011) Yifat Miller et al.   BIOCHEMISTRY

Prediction of the aggregation propensity of proteins from the primary sequence: Aggregation properties of proteomes

(2011) Virginia Castillo et al.   Biotechnology Journal

Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins

(2011) Randal Halfmann et al.   MOLECULAR CELL

Structural Similarity between the Prion Domain of HET-s and a Homologue Can Explain Amyloid Cross-Seeding in Spite of Limited Sequence Identity

(2010) Christian Wasmer et al.   JOURNAL OF MOLECULAR BIOLOGY

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

The effects of amino acid composition on yeast prion formation and prion domain interactions

(2010) Eric D. Ross et al.   Prion

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

Compositional Determinants of Prion Formation in Yeast

(2009) J. A. Toombs et al.   MOLECULAR AND CELLULAR BIOLOGY

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids

(2009) Adriano Aguzzi et al.   NEURON

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short protein segments can drive a non-fibrillizing protein into the amyloid state

(2009) P. K. Teng et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Amyloid Fibrils of the HET-s(218-289) Prion Form a   Solenoid with a Triangular Hydrophobic Core

(2008) C. Wasmer et al.   SCIENCE