Variations in the Binding Pocket of an Inhibitor of the Bacterial Division Protein FtsZ across Genotypes and Species

Bacterial cell division as a target for new antibiotics

(2013) Peter Sass et al.   CURRENT OPINION IN MICROBIOLOGY

Structural Change in FtsZ Induced by Intermolecular Interactions between Bound GTP and the T7 Loop

(2013) Takashi Matsui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liposome division by a simple bacterial division machinery

(2013) M. Osawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FtsZ Protofilaments Use a Hinge-Opening Mechanism for Constrictive Force Generation

(2013) Y. Li et al.   SCIENCE

Mechanism of Action of the Cell-Division Inhibitor PC190723: Modulation of FtsZ Assembly Cooperativity

(2012) Nathaniel L. Elsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleotide-dependent conformations of FtsZ dimers and force generation observed through molecular dynamics simulations

(2012) J. Hsin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution and Organization ofEscherichia coliProto-ring Elements (FtsZ and FtsA) inside Giant Unilamellar Vesicles Obtained from Bacterial Inner Membranes

(2011) Mercedes Jiménez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using Multiple Microenvironments to Find Similar Ligand-Binding Sites: Application to Kinase Inhibitor Binding

(2011) Tianyun Liu et al.   PLoS Computational Biology

The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation

(2010) José M. Andreu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Creating an Antibacterial with in Vivo Efficacy: Synthesis and Characterization of Potent Inhibitors of the Bacterial Cell Division Protein FtsZ with Improved Pharmaceutical Properties

(2010) David J. Haydon et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer

(2009) Amy Raymond et al.   BMC BIOTECHNOLOGY

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Berberine Targets Assembly of Escherichia coli Cell Division Protein FtsZ†

(2008) Prerna N. Domadia et al.   BIOCHEMISTRY

Reconstitution of Contractile FtsZ Rings in Liposomes

(2008) M. Osawa et al.   SCIENCE

An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity

(2008) D. J. Haydon et al.   SCIENCE