Article
Food Science & Technology
Jaroslawa Rutkowska, Damian Baranowski, Agata Antoniewska-Krzeska, Eliza Kostyra, Maria Tufariello
Summary: Excessive consumption of simple sugars can lead to non-communicable diseases. Xylitol is a valuable sweetener alternative with anticarcinogenic and prebiotic-like characteristics, and lower glycaemic index and caloric value. This study found that using xylitol as a sucrose alternative improved the storage effects and sensory profiles of cookies.
Article
Multidisciplinary Sciences
Sara K. Jones, Deirdre M. McCarthy, Cynthia Vied, Gregg D. Stanwood, Chris Schatschneider, Pradeep G. Bhide
Summary: This study reports the effects of aspartame on anxiety-like behavior, neurotransmitter signaling, and gene expression in the amygdala. Mice drinking water with aspartame exhibited anxiety-like behavior and had altered gene expression in the amygdala. The changes in behavior and gene expression were also observed in the offspring.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Nutrition & Dietetics
Yuraporn Sahasakul, Wannee Angkhasirisap, Aroonwan Lam-Ubol, Amornrat Aursalung, Daisuke Sano, Kentaro Takada, Dunyaporn Trachootham
Summary: This study found that substituting glucose with xylitol can slow down tumor growth, prolong survival time, and inhibit the expression of glycolytic enzymes. This discovery provides a basis for considering xylitol as a sweetener in food products for cancer survivors.
Article
Nutrition & Dietetics
Bereket Gebremichael, Zohra S. Lassi, Mumtaz Begum, Murthy Mittinty, Shao-Jia Zhou
Summary: This study investigated the consumption patterns and predictors of low-calorie sweeteners (LCS) among pregnant women in Australia. The results showed that over half of the pregnant women were infrequent or non-consumers of LCS, while approximately 40% were moderate consumers and the remaining were habitual consumers. Moreover, more than 70% of the women were not aware of the potential adverse effects of LCS and lacked concern about its impacts on their health and their offspring.
Article
Environmental Sciences
Xiaopeng Yu, Furong Yu, Zhiping Li, Tongyang Shi, Zhiguo Xia, Guangning Li
Summary: This study investigated the occurrence and distribution of four commonly used artificial sweeteners (ASs) in the effluent of wastewater treatment plants, surface water, and groundwater in the middle and lower reaches of the Yellow River. The results showed that sucralose was dominant in wastewater treatment plant effluents and had the highest mass loading. ACE, CYC, SAC, and SUC were consistently detected in surface water. The risk assessment indicated that the risks of these ASs to aquatic organisms were negligible.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Biotechnology & Applied Microbiology
Italo de Andrade Bianchini, Fanny Machado Jofre, Sarah de Souza Queiroz, Talita Martins Lacerda, Maria das Gracas de Almeida Felipe
Summary: One of the critical steps in the biotechnological production of xylitol is the deconstruction of the plant cell wall, which is necessary for the conversion of xylose to xylitol by yeasts. However, toxic compounds released during pretreatment inhibit xylitol production, affecting yeast physiology and metabolism. Understanding the mechanism of toxicity and developing strategies for yeast adaptation are important for overcoming this bottleneck in xylitol production.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Medicine, Research & Experimental
Ruben de Dios, Chris R. Proctor, Evgenia Maslova, Sindija Dzalbe, Christian J. Rudolph, Ronan R. McCarthy
Summary: Research has found that three artificial sweeteners have antimicrobial effects on priority pathogens, and one of them can disable virulence behaviors of multidrug-resistant Acinetobacter baumannii. The mechanism involves cell lysis mediated by bulge and can be rescued by cation supplementation. Moreover, this sweetener can resensitize A. baumannii to last resort antibiotics and maintain antimicrobial activity in the wound microenvironment.
EMBO MOLECULAR MEDICINE
(2023)
Article
Engineering, Environmental
Chan-Chiung Liu, Chien-Hsuan Ko, Yao-Nan Wang, Lung-Ming Fu, Sheng-Zhuo Lee
Summary: The study introduced a microfluidic chromatography detection system for simultaneous concentration determination of saccharin sodium and acesulfame potassium. The system showed reliable detection performance and results were within 6.3% of traditional HPLC systems when tested on commercial food samples.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Food Science & Technology
Kai Buechner, Jana Haagen, Ashtri Sastrosubroto, Roland Kerpes, Jessica Freiherr, Thomas Becker
Summary: Consumer health concerns and regulatory policies have led to an increased demand for alternatives to sugar-sweetened beverages. Artificial sweeteners can reduce the calorie content, but they may also introduce metallic or bitter off-flavors. This study explores the impact of menthol on sweetness perception in an aqueous solution, finding that it has no sensory effect but enhances the physiological response to cold perception and masks the bitterness of a sweetener.
Article
Agriculture, Dairy & Animal Science
Nannicha Tinted, Smith Pongcharoenwanit, Thodsapol Ongvisespaibool, Veerada Wachirodom, Taksaon Jumnansilp, Narinthip Buckland, Piyathip Chuchalermporn, Sirikul Soontararak, Selapoom Pairor, Joerg M. Steiner, Naris Thengchaisri, Sathidpak Nantasanti Assawarachan
Summary: Steroid-induced hepatopathy is an important liver abnormality in dogs with hyperadrenocorticism (HAC). This study evaluated the serum total bile acids concentrations and liver enzyme activities in dogs with HAC following trilostane treatment. The results showed that low-dose trilostane treatment for 3 months appeared to reduce the serum liver enzyme activities, but not the serum total bile acids concentrations.
Article
Engineering, Environmental
Mark Honti, Marton Zsugyel, Carolin Seller, Kathrin Fenner
Summary: This study developed the concept of persistence benchmarking for organic micropollutants in large rivers. By observing the dissipation rates of compounds, the researchers were able to distinguish between fast- and slow-degrading compounds and provide reasonable estimates on system half-lives.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Agricultural Engineering
Vishal Ahuja, Diptarka Dasgupta, Siddheshwar Kshirsagar, Prasenjit Ghosh, Snehal More, Piyush Gupta, Babita Behera, Thallada Bhaskar
Summary: This study demonstrates a method for producing food-grade xylitol from corncob biomass and reducing energy consumption through process modifications. The results show that high-yield and high-purity xylitol crystals can be produced using a non-conventional fermentation strategy and a combination of membrane-based filtration and crystallization.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Nutrition & Dietetics
Juan Carlos Borquez, Miltha Hidalgo, Juan M. Rodriguez, Alejandra Montana, Omar Porras, Rodrigo Troncoso, Roberto Bravo-Sagua
Summary: Short-term exposure to low doses of sucralose can increase mitochondrial respiratory activity and enhance cellular reductive power in Caco-2 cells. These findings suggest that sucralose alters enterocyte energy homeostasis, contributing to its effects on organismal metabolism.
FRONTIERS IN NUTRITION
(2021)
Article
Physiology
Wojciech Wolyniec, Andrzej Szwarc, Katarzyna Kasprowicz, Katarzyna Zorena, Marta Jaskulak, Marcin Renke, Marta Naczyk, Wojciech Ratkowski
Summary: Proper fluid and carbohydrate intake is crucial before and during physical exercise. Most athletes consume beverages with high levels of free sugars. Sweetened soft drinks, which are also consumed by non-athletes, are unhealthy and can lead to metabolic problems. This study examined the impact of free sugars and the sweetener xylitol on metabolic profile and kidney function and injury markers in semi-professional football players. Results showed that xylitol was the least tolerated during exercise, leading to diarrhea and unfavorable metabolic changes. The study concludes that sweeteners are not a good alternative to sugars, especially during exercise, and that individuals looking to limit calorie consumption should opt for pure water.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Food Science & Technology
Xiaoyi He, Qianyi Zhong, Kai Yan, Guoying Li, Junhua Yang
Summary: This study aimed to investigate the effect of exposure to aspartame at safe levels on proinflammatory cytokines in the cerebrospinal fluid of rats. The results showed that exposure to aspartame increased the levels of proinflammatory cytokines in the cerebrospinal fluid, with a delay compared to blood and brain tissue. This study suggests the necessity of conducting clinical studies to evaluate potential neuroinflammatory effects induced by chronic aspartame exposure through cerebrospinal fluid analysis.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Veterinary Sciences
Pamela Caye, Josaine Cristina da Silva Rappeti, Soliane Carra Perera, Hecson Jesser Segat, Patricia Silva Vives, Fabricio de Vargas Arigony Braga, Marlete Brum Cleff, Ana Raquel Mano Meinerz, Guilherme Albuquerque de Oliveira Cavalcanti, Vanessa Milech, Bernardo Nascimento Antunes, Daniel Curvello de Mendonca Muller, Mauricio Veloso Brun
Summary: This retrospective study evaluated the epidemiological, clinical, and surgical aspects of dogs infected with D. renale undergoing therapeutic nephrectomy. The study found that surgical removal of the affected kidney effectively controlled the parasitic infection and resulted in a relatively long postoperative survival time.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)
Review
Veterinary Sciences
Karine Cristine Almeida, Fernanda Pinto-Ferreira, Italmar Teodorico Navarro, Kamila Libano Souza, Leticia Santos Balbino, Juliana Correa Bernardes, Danielle Louisy Bahia dos Santos, Margarete Kimie Falbo
Summary: This study aimed to investigate the occurrence of zoonotic enteroparasites in dog feces from public places in Guarapuava, Brazil, and assess the knowledge of dog owners about zoonoses and public health risks. The results showed a high infection rate of zoonotic parasites in dog feces collected from public shelters, squares, parks, and roads. The survey also revealed that some dog owners did not collect their animals' feces, did not administer deworming treatments to their dogs, and were unaware of the diseases transmitted by feces.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)
Review
Veterinary Sciences
Deeksha Bharti, Y. Ajith, Khan Sharun, S. Amitha Banu, Akshay Kumar, Abhishek Bhardwaj, Shiv Kumar Sidar
Summary: Platelet-derived products have significant potential in regenerative medicine, particularly in tissue regeneration and complementary therapy. They offer a cost-effective and easily accessible therapeutic option for chronic inflammatory disorders, ophthalmic conditions, wound healing, and mandibular injuries in canine patients. Further research and exploration are necessary to fully understand the preparation and applicability of platelet products in canine medicine.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)
Article
Veterinary Sciences
Doroteja Huber, Kresimir Severin, Dunja Vlahovic, Stefani Krizanac, Sanja Mofardin, Ivana Mihokovic Buhin, Lidija Medven Zagradisnik, Ivan-Conrado Sostaric-Zuckermann, Andrea Gudan Kurilj, Branka Artukovic, Marko Hohsteter
Summary: This is a retrospective study on tumor prevalence in cats in Croatia, providing abundant histopathology findings and epidemiological data. It offers valuable insights into the most common tumors in cats from south-eastern Europe, contributing to the field of clinical veterinary oncology.
TOPICS IN COMPANION ANIMAL MEDICINE
(2024)
