Catalyst compartmentalization in Dynamic Kinetic Resolutions

Catalytic nanoreactors, prepared by encapsulation of Zeolite H-Beta using a Layer-by-Layer (LbL) assembly of polyelectrolytes, have been examined in the Dynamic Kinetic Resolution (DKR) of secondary alcohols. The encapsulation of the acidic zeolite racemisation catalyst protects the pH-sensitive enzyme. This approach represents a convenient method of catalyst protection in multi-catalyst systems.