Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis

A Systems Biology Approach to the Analysis of Subset-Specific Responses to Lipopolysaccharide in Dendritic Cells

(2014) David G. Hancock et al.   PLoS One

CD141+ dendritic cells produce prominent amounts of IFN-  after dsRNA recognition and can be targeted via DEC-205 in humanized mice

(2013) S. Meixlsperger et al.   BLOOD

Glucocorticoid receptor translational isoforms underlie maturational stage-specific glucocorticoid sensitivities of dendritic cells in mice and humans

(2013) Y. Cao et al.   BLOOD

Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

(2013) G. Nizzoli et al.   BLOOD

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View

(2013) Wibke Schulte et al.   MEDIATORS OF INFLAMMATION

Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness

(2012) Paul R. Mittelstadt et al.   JOURNAL OF CLINICAL INVESTIGATION

Lyn-Dependent Signaling Regulates the Innate Immune Response by Controlling Dendritic Cell Activation of NK Cells

(2012) D. L. Krebs et al.   JOURNAL OF IMMUNOLOGY

It takes two to tango: Dimerisation of glucocorticoid receptor and its anti-inflammatory functions

(2012) Mark Nixon et al.   STEROIDS

The inflammatory response in sepsis

(2012) Markus Bosmann et al.   TRENDS IN IMMUNOLOGY

Systemic Steroids in Severe Sepsis and Septic Shock

(2011) Gourang P. Patel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adrenocortical (dys)function in septic shock - A sick euadrenal state

(2011) Bala Venkatesh et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammation

(2011) M. Chen et al.   BLOOD

Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages

(2011) Anna Kleiman et al.   FASEB JOURNAL

Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells

(2011) U. Baschant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CD8+dendritic cell subset

(2010) Ken Shortman et al.   IMMUNOLOGICAL REVIEWS

Characterization of human DNGR-1+BDCA3+leukocytes as putative equivalents of mouse CD8α+dendritic cells

(2010) Lionel Franz Poulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Marked Reduction in Priming of Cytotoxic CD8+ T Cells Mediated by Stress-Induced Glucocorticoids Involves Multiple Deficiencies in Cross-Presentation by Dendritic Cells

(2010) J. T. Hunzeker et al.   JOURNAL OF IMMUNOLOGY

Resident and Monocyte-Derived Dendritic Cells Become Dominant IL-12 Producers under Different Conditions and Signaling Pathways

(2010) Y. Zhan et al.   JOURNAL OF IMMUNOLOGY

Role of glucocorticoids and the glucocorticoid receptor in metabolism: Insights from genetic manipulations

(2010) Adam J. Rose et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The role of the glucocorticoid receptor in inflammation and immunity

(2010) Ulrike Baschant et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Interferon   induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation

(2009) J.-H. Yen et al.   BLOOD

Toll-Like Receptors 2 and 4 Contribute to Sepsis-Induced Depletion of Spleen Dendritic Cells

(2009) F. Pene et al.   INFECTION AND IMMUNITY

Type I interferon drives tumor necrosis factor–induced lethal shock

(2009) Liesbeth Huys et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of an Immediate Splenic Precursor of CD8+ Dendritic Cells Capable of Inducing Antiviral T Cell Responses

(2009) S. Bedoui et al.   JOURNAL OF IMMUNOLOGY

CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation

(2009) Ivan Zanoni et al.   NATURE

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

NK cells interactions with dendritic cells shape innate and adaptive immunity

(2008) Fabienne Brilot   Frontiers in Bioscience-Landmark

Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells

(2007) M. Illario et al.   BLOOD