CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila

Ecdysone and Mediator Change Energy Metabolism to Terminate Proliferation in Drosophila Neural Stem Cells

(2014) Catarina C.F. Homem et al.   CELL

All-atomic molecular dynamic studies of human CDK8: Insight into the A-loop, point mutations and binding with its partner CycC

(2014) Wu Xu et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

The Mediator complex: a master coordinator of transcription and cell lineage development

(2014) J.-w. Yin et al.   DEVELOPMENT

Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues

(2014) Abigail Aleman et al.   Scientific Reports

Transcriptional Control of Steroid Biosynthesis Genes in the Drosophila Prothoracic Gland by Ventral Veins Lacking and Knirps

(2014) E. Thomas Danielsen et al.   PLoS Genetics

The Mediator complex and transcription regulation

(2013) Zachary C. Poss et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genetic Control of Specificity to Steroid-Triggered Responses in Drosophila

(2013) R. J. Ihry et al.   GENETICS

Coordination of organ growth: principles and outstanding questions from the world of insects

(2013) D.S. Andersen et al.   TRENDS IN CELL BIOLOGY

A Drosophila Model of High Sugar Diet-Induced Cardiomyopathy

(2013) Jianbo Na et al.   PLoS Genetics

Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research

(2012) Naoki Yamanaka et al.   Annual Review of Entomology

The Mediator complex in thyroid hormone receptor action

(2012) Joseph D. Fondell   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of lipogenesis by cyclin-dependent kinase 8–mediated control of SREBP-1

(2012) Xiaoping Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

High Sugar-Induced Insulin Resistance in Drosophila Relies on the Lipocalin Neural Lazarillo

(2012) Matthieu Y. Pasco et al.   PLoS One

Identification of common and cell type specific LXXLL motif EcR cofactors using a bioinformatics refined candidate RNAi screen in Drosophila melanogaster cell lines

(2011) Melissa B Davis et al.   BMC DEVELOPMENTAL BIOLOGY

Coordinating Growth and Maturation — Insights from Drosophila

(2011) Jason M. Tennessen et al.   CURRENT BIOLOGY

Function and regulation of the Mediator complex

(2011) Ronald C Conaway et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Neuroendocrine regulation of Drosophila metamorphosis requires TGF /Activin signaling

(2011) Y. Y. Gibbens et al.   DEVELOPMENT

A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila

(2011) L. Palanker Musselman et al.   Disease Models & Mechanisms

Regulation of Androgen Receptor and Prostate Cancer Growth by Cyclin-dependent Kinase 5

(2011) Fu-Ning Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dysregulation of CDK8 and Cyclin C in tumorigenesis

(2011) Wu Xu et al.   Journal of Genetics and Genomics

The Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder

(2011) E.V. Schneider et al.   JOURNAL OF MOLECULAR BIOLOGY

Control of Drosophila endocycles by E2F and CRL4CDT2

(2011) Norman Zielke et al.   NATURE

A genome-scale shRNA resource for transgenic RNAi in Drosophila

(2011) Jian-Quan Ni et al.   NATURE METHODS

dDOR Is an EcR Coactivator that Forms a Feed-Forward Loop Connecting Insulin and Ecdysone Signaling

(2010) Víctor A. Francis et al.   CURRENT BIOLOGY

Steroid Hormone Inactivation Is Required during the Juvenile-Adult Transition in Drosophila

(2010) Kim F. Rewitz et al.   DEVELOPMENTAL CELL

Med24andMdh2are required forDrosophilalarval salivary gland cell death

(2010) Lei Wang et al.   DEVELOPMENTAL DYNAMICS

The human Mediator complex: a versatile, genome-wide regulator of transcription

(2010) Dylan J. Taatjes   TRENDS IN BIOCHEMICAL SCIENCES

Molecular mechanisms of metabolic regulation by insulin inDrosophila

(2009) Aurelio A. Teleman   BIOCHEMICAL JOURNAL

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

Arthropod nuclear receptors and their role in molting

(2009) Yoshiaki Nakagawa et al.   FEBS Journal

A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor

(2009) S. Sawatsubashi et al.   GENES & DEVELOPMENT

Indirect immune detection of ecdysone receptor (EcR) during the formation of DNA puffs in Bradysia hygida (Diptera, Sciaridae)

(2008) Juliana Aparecida Candido-Silva et al.   CHROMOSOME RESEARCH

Smt3 is required for Drosophila melanogaster metamorphosis

(2008) A. Talamillo et al.   DEVELOPMENT

The TOR Pathway Couples Nutrition and Developmental Timing in Drosophila

(2008) Sophie Layalle et al.   DEVELOPMENTAL CELL

A Genetic Screen Identifies New Regulators of Steroid-Triggered Programmed Cell Death in Drosophila

(2008) L. Wang et al.   GENETICS

Phosphoproteome Analysis ofDrosophila melanogasterEmbryos

(2008) Bo Zhai et al.   JOURNAL OF PROTEOME RESEARCH

The Human CDK8 Subcomplex Is a Histone Kinase That Requires Med12 for Activity and Can Function Independently of Mediator

(2008) M. T. Knuesel et al.   MOLECULAR AND CELLULAR BIOLOGY

Heterochromatin Protein 1a Stimulates Histone H3 Lysine 36 Demethylation by the Drosophila KDM4A Demethylase

(2008) Chia-Hui Lin et al.   MOLECULAR CELL

E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8

(2008) Erick J. Morris et al.   NATURE

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

(2008) Henri-Marc Bourbon   NUCLEIC ACIDS RESEARCH