Article
Engineering, Biomedical
R. Tevlin, H. desJardins-Park, J. Huber, S. E. DiIorio, M. T. Longaker, D. C. Wan
Summary: Osteoarthritis is a global burden that affects joints and bones. Tissue engineering, specifically adipose-derived stromal cells, shows promise as a treatment option. Advancements in material science allow for improved engraftment of these cells and activation of biophysical signals through designed microstructures.
Article
Cell & Tissue Engineering
Tomoyuki Kamenaga, Yuichi Kuroda, Kanto Nagai, Masanori Tsubosaka, Yoshinori Takashima, Kenichi Kikuchi, Masahiro Fujita, Kemmei Ikuta, Kensuke Anjiki, Toshihisa Maeda, Naoki Nakano, Koji Takayama, Shingo Hashimoto, Shinya Hayashi, Takehiko Matsushita, Takahiro Niikura, Ryosuke Kuroda, Tomoyuki Matsumoto
Summary: The study found that SVF cells can enhance bone healing, with cryopreserved cells showing almost equal potential as fresh cells. SVF cells can be used to improve nonunion bone fracture healing as an alternative to other mesenchymal stem cells, and their effect can be maintained under cryopreservation.
STEM CELL RESEARCH & THERAPY
(2021)
Review
Cell Biology
Yuan Liu, Christina Holmes
Summary: This review explores the tissue regeneration potential of EVs isolated from bone marrow and adipose tissue, the two most common clinical sources of adult MSCs, focusing on their angiogenic, osteogenic, and immunomodulatory potentials. Other important issues in the development of MSC-derived EV based therapies are also discussed.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Seong Chae Park, Woo Sub Yang, Ji Yeon Ahn, Jong Bo Park, Jong-Hwan Lee, Youngjin Jung, Hwa Rang Kim, Ji Yoon Kim, Jeong Mook Lim, Byung Hee Hong
Summary: This study investigated the potential of hydroxyapatite-mineralized graphene film to support osteogenic differentiation of human adipose-derived stromal cells in vitro. Results indicated that the optimized treatment promoted cell proliferation and osteogenic differentiation of hASCs through the BMP/Smad signaling pathway.
Article
Food Science & Technology
Lunan Guo, Xin-Mei Nie, Ya-Hui Yang, Yiping Ren, Xiangli Ding, Jian-Ya Qian
Summary: This study investigated the effects of pulsed electric field (PEF) and low direct current electric field (DCEF) on the water-holding capacity (WHC), oil-holding capacity (OHC), microstructure, texture, and physical structure of wheat gluten. The results showed that both PEF and DCEF significantly influenced WHC and OHC. PEF had a smaller impact on textural properties, while DCEF had a stronger impact on all textural indices. Scanning electron microscopy revealed that PEF caused smaller and uniform micropores, while DCEF resulted in a more continuous and compact microstructure. Fourier transform infrared spectrometry indicated that the electric fields altered the composition proportion of the secondary structure significantly. UV and fluorescence spectra showed slight shifts, and surface hydrophobicity of gluten increased after electric field treatment. X-ray diffractometry demonstrated that the electric field made the physical structure of wet gluten more compact. Overall, this study suggests that electric field treatment holds promise for vegetable protein texturisation.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2023)
Review
Medicine, General & Internal
Robert Ossendorff, Alessandra Menon, Frank A. Schildberg, Pietro S. Randelli, Sebastian Scheidt, Christof Burger, Dieter C. Wirtz, Davide Cucchi
Summary: The global distribution and quality of studies using adipose tissue derivates in orthopedics were assessed through a systematic review. Among the 82 included studies, 70% focused on knee disorders, mainly osteoarthritis. Approximately 26% of the studies investigated expanded adipose-derived stem/stromal cells (ADSCs), with 72% of these using stromal vascular fraction (SVF). The overall quality of the studies varied, with a higher score found in studies involving expanded ADSCs compared to SVF.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Chemistry, Physical
Feilong Dong, Zhen Pang, Qiufeng Lin, Da Wang, Xiaoyan Ma, Shuang Song, Shuangxi Nie
Summary: In this study, a self-powered photoelectric catalysis system using a spherical triboelectric nanogenerator was developed to improve the removal rate of Atrazine. The system showed significant enhancements in the removal and mineralization of Atrazine under a pulsed direct-current electric field. The degradation mechanism and pathway of Atrazine were investigated through experiments and calculations. This research provides a novel strategy for enhancing the performance of self-powered photoelectric catalysis processes for wastewater treatment.
Article
Chemistry, Multidisciplinary
Gaocai Li, Qianqian Zhu, Bingjin Wang, Rongjin Luo, Xiaohui Xiao, Yi Zhang, Liang Ma, Xiaobo Feng, Jingang Huang, Xuhui Sun, Zhen Wen, Yue Pan, Cao Yang
Summary: The study introduces a new method for rejuvenating senescent bone marrow mesenchymal stromal cells (BMSCs) using pulsed triboelectric stimulation. This approach reverses the senescence phenotypes of aged BMSCs, enhances their proliferation and pluripotency, and rejuvenates them by enhancing MDM2-dependent p53 degradation through pulsed triboelectric stimulation by P-TENG.
Article
Instruments & Instrumentation
Wenqi Wei, Ming Yang, Shimin Jin, Haipeng Zhu, Junfeng Wang, Xiaotao Han
Summary: Investigation of non-ohmic transport behaviors under high magnetic fields can lead to the exploration of novel field-induced phenomena. In this study, current-voltage measurements under high magnetic fields were conducted using a flat-top pulsed magnetic field system. Two different measurement strategies were compared, and the non-ohmic behaviors of a quasi-one-dimensional charge density wave material were successfully studied.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2022)
Article
Multidisciplinary Sciences
Jana Klaus, Dennis J. L. G. Schutter
Summary: Research compared different electrode placements on the effects of electric field distribution and direction induced by tDCS, indicating that placing smaller electrodes closer to the target area significantly reduces extracerebellar electric fields and improves the focality of current flow.
SCIENTIFIC REPORTS
(2021)
Review
Biochemistry & Molecular Biology
Matteo Guidetti, Stefano Giannoni-Luza, Tommaso Bocci, Kevin Pacheco-Barrios, Anna Maria Bianchi, Marta Parazzini, Silvio Ionta, Roberta Ferrucci, Natale Vincenzo Maiorana, Federico Verde, Nicola Ticozzi, Vincenzo Silani, Alberto Priori
Summary: Clinical findings suggest that transcutaneous spinal direct current stimulation (tsDCS) can modulate ascending sensitive, descending corticospinal, and segmental pathways in the spinal cord (SC). Realistic computational models based on MRI can predict the interaction between tsDCS-induced electric fields and anatomy. Understanding the electric field distribution in the spinal cord and its relation to clinical findings is important for optimizing tsDCS protocols.
Review
Chemistry, Physical
Lei Chen, Jin-Tao Ren, Zhong-Yong Yuan
Summary: In recent years, there has been a growing interest in utilizing advanced photo-/electrocatalysts for efficient energy conversion and environmental remediation. The construction of internal electric fields has emerged as a promising technique for enhancing various catalytic processes. This review provides a comprehensive overview of the latest advances in constructing internal electric fields and their impact on photo(electro)catalytic and electrocatalytic activity, as well as their potential applications in energy and environmental fields.
ADVANCED ENERGY MATERIALS
(2023)
Article
Multidisciplinary Sciences
Angela Serena Maione, Viviana Meraviglia, Lara Iengo, Martina Rabino, Mattia Chiesa, Valentina Catto, Claudio Tondo, Giulio Pompilio, Milena Bellin, Elena Sommariva
Summary: Primary cardiac mesenchymal stromal cells (C-MSCs) and hiPSC-derived stromal cells can be used to model arrhythmogenic cardiomyopathy by differentiating into adipocytes and myofibroblasts. Both types of cells express mesenchymal surface markers, possess MSC differentiation potentials, and exhibit similar transcriptomic profiles. The choice of model depends on experimental needs and sample availability.
SCIENTIFIC REPORTS
(2023)
Article
Biology
Kejia Li, Litong Fan, Jianjing Lin, Boon Chin Heng, Zhantao Deng, Qiujian Zheng, Jue Zhang, Yangzi Jiang, Zigang Ge
Summary: Mesenchymal stem cells (MSCs) can benefit from enhanced chondrogenesis through the combination of nanosecond pulsed electric fields and ghrelin. The sequential order of applying these two stimuli is crucial for promoting cartilage regeneration. This study provides new insights and strategies for future cell-based therapies.
SCIENCE CHINA-LIFE SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Giusi Alberti, Eleonora Russo, Simona Corrao, Rita Anzalone, Peter Kruzliak, Vitale Miceli, Pier Giulio Conaldi, Francesca Di Gaudio, Giampiero La Rocca
Summary: Extracellular vesicles (EVs) are one of the main mechanisms of communication between cells and the surrounding tissue or at distance. Recent studies have revealed the molecular composition and clinical indications of EVs derived from adult mesenchymal stromal cells (MSCs). These EVs maintain some of the properties of their parent cells and have important implications for cell-free therapies.