Article
Orthopedics
Chenhao Dou, Tianhua Li, Shuhong Yang, Qian Geng, Qing Lu, Yahui Zhang, Jingjing Yu, Fang Hu, Junqin Ding
Summary: This study investigated the incidence and risk factors of deep vein thrombosis (DVT) in patients with femoral neck fracture. The results showed a relatively high incidence of DVT in these patients, with multiple related risk factors.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Hematology
Alvaro Dubois-Silva, Cristina Barbagelata-Lopez, Patricia Pineiro-Parga, Iria Francisco, Conxita Falga, Raimundo Tirado, Jose Maria Surinach, Jeronimo Ramon Vela, Carmen Mella, Isabelle Quere, Carmine Siniscalchi, Manuel Monreal
Summary: Compared to patients with isolated DVT, those with concomitant SVT in lower-limb deep vein thrombosis have a higher risk of subsequent pulmonary embolism, but no significant differences in rates of recurrent DVT, major bleeding, or death.
THROMBOSIS AND HAEMOSTASIS
(2021)
Article
Hematology
Giacomo Turatti, Ugo Fedeli, Luca Valerio, Frederikus A. Klok, Alexander T. Cohen, Beverley J. Hunt, Paolo Simioni, Saskia Middeldorp, Walter Ageno, Nils Kucher, Stavros Konstantinides, Elena Schievano, Stefano Barco
Summary: A study in the Veneto region of Italy from 2008 to 2019 found that the mortality rate related to splanchnic vein thrombosis (SVT) showed different trends, with an average annual increase of 5.7% in women and a decrease of 1.2% in men. Concurrent liver disease and gastrointestinal cancers are associated with SVT-related death to some extent.
THROMBOSIS RESEARCH
(2022)
Article
Health Care Sciences & Services
Jang-Hyuk Cho, Dong-Gyu Lee
Summary: Based on a retrospective analysis of patients with spinal cord injury from 2016 to 2020, Asian patients with spinal cord injury have a low incidence of below-knee deep vein thrombosis and a favorable natural history of the condition, recommending serial imaging over anticoagulant therapy for these patients.
Article
Biotechnology & Applied Microbiology
Hongtao Dai, Senlin Chai, Yao Yao, Wenlai Tang, Jianping Shi, Qing Jiang, Liya Zhu
Summary: In this study, researchers investigated the mechanism of action of intermittent pneumatic compression (IPC) devices on deep vein thrombosis (DVT) using microfluidic chip methodology. The results showed that increasing compression pressure and reducing time intervals can accelerate blood flow rate and shear stress within the vein, reducing thrombosis formation. This study is important for further standardization and optimization of IPC devices in clinical usage.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Immunology
Mengting Yao, Jiacheng Ma, Dongwen Wu, Chucun Fang, Zilong Wang, Tianting Guo, Jianwen Mo
Summary: Deep venous thrombosis (DVT) is a part of venous thromboembolism (VTE) that presents as swelling and pain in the lower limbs. The most serious complication of DVT is pulmonary embolism (PE) with high mortality. Understanding the underlying mechanisms of DVT is crucial for early diagnosis and treatment as patients usually show clinical symptoms after thrombus formation.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Hematology
Danielle T. Vlazny, Ahmed K. Pasha, Wiktoria Kuczmik, Waldemar E. Wysokinski, Matthew Bartlett, Damon Houghton, Ana Casanegra, Paul Daniels, David A. Froehling, Launia J. White, David O. Hodge, Robert D. McBane
Summary: IDDVT patients were more likely associated with recent surgery, major trauma, or confinement, while PDVT patients were more likely unprovoked, had a prior history of VTE, or active cancer. During follow-up, there was no significant difference in VTE recurrence or major bleeding between groups, but IDDVT patients had a higher mortality rate, which was positively impacted by DOAC therapy that also led to lower rates of VTE recurrence, major bleeding, and death in both groups.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2021)
Article
Surgery
Pavel Kibrik, Michael Arustamyan, Ahmad Alsheekh, Yuriy Ostrozhynskyy, Vera Rabinovich, Natalie Marks, Anil Hingorani, Enrico Ascher
Summary: Iliac vein stenting is a safe and effective procedure for correcting iliac vein stenosis, but one major complication is the formation of iliac vein stent thrombosis. This study found that some patients developed early partial in-stent thrombosis. Patients with ASA scores of 2 or 3 were more likely to develop partial thrombosis, while male gender was associated with partial thrombus resolution.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Oncology
Philippe Debourdeau, Laurent Bertoletti, Carme Font, Juan Jose Lopez-Nunez, Covadonga Gomez-Cuervo, Isabelle Mahe, Remedios Otero-Candelera, Maria Dolores Adarraga, Patricia Lopez-Miguel, Manuel Monreal
Summary: This study compared the clinical characteristics and 90-day outcomes of cancer patients with lower-limb isolated superficial vein thrombosis (SVT) and deep vein thrombosis (DVT), and found that the risk for subsequent venous thromboembolism (VTE) was similar in both groups.
Article
Psychiatry
Nai-Chen Shih, Liang-Tsai Yeh, Bo-Yuan Wang, Yu-Hsun Wang, Shun-Fa Yang, Chao-Bin Yeh
Summary: This study, using a health insurance database in Taiwan, found an association between benzodiazepine use and an increased risk of deep vein thrombosis, with a dose-dependent relationship. It highlights the importance of evaluating benzodiazepine prescription to reduce the risk of developing DVT.
PSYCHIATRY RESEARCH
(2023)
Review
Medicine, General & Internal
Oneib Khan, Ashley Marmaro, David A. Cohen
Summary: This review provides a comprehensive overview of upper extremity deep vein thrombosis (UEDVT), covering its epidemiology, pathophysiology, risk factors, presentation, complications, evaluation/diagnosis, and treatment. UEDVT accounts for 6% of DVT cases, with potential complications including pulmonary embolism. Evaluation typically involves Constans score and fibrin degradation product testing, while diagnosis is usually made through compression ultrasound.
POSTGRADUATE MEDICINE
(2021)
Article
Geriatrics & Gerontology
Hao-Ran Cheng, Gui-Qian Huang, Zi-Qian Wu, Yue-Min Wu, Gang-Qiang Lin, Jia-Ying Song, Yun-Tao Liu, Xiao-Qian Luan, Zheng-Zhong Yuan, Wen-Zong Zhu, Jin-Cai He, Zhen Wang
Summary: This study established and validated a nomogram for predicting the risk of early IDDVT in AIS patients, based on independent risk factors including age, gender, lower limb paralysis, current pneumonia, atrial fibrillation, and malignant tumor. The nomogram showed high predictive accuracy in both training and validation cohorts, with AUROC values of 0.767 and 0.820 respectively.
Article
Cardiac & Cardiovascular Systems
Xiaojie Liu, Tiajun Li, Hui Xu, Chunhua Wang, Xiaojun Ma, Hui Huang, Yanling Hu, Haichen Chu
Summary: This study found an association between preoperative hyperglycemia and deep vein thrombosis (DVT) in trauma patients undergoing surgery for lower limb fractures. Age, D-dimer level, preoperative RBC count, and preoperative glucose level were identified as independent predictors of DVT.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Ahmed K. Pasha, Wiktoria Kuczmik, Waldemar E. Wysokinski, Ana I. Casanegra, Damon Houghton, Danielle T. Vlazny, Abigail Mertzig, Yumiko Hirao-Try, Launia White, David Hodge, Robert McBane
Summary: The study compared outcomes between cancer patients with calf DVT and those without cancer. Cancer patients with calf DVT had similar rates of VTE recurrence but higher major bleeding outcomes compared to patients without cancer.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2021)
Article
Medical Laboratory Technology
Chaoqin Mao, Yueshan Xiong, Cheng Fan
Summary: The research compared thromboelastography (TEG) and conventional coagulation assays (CCAs) in identifying deep vein thrombosis (DVT) and evaluating coagulation status. Results showed that TEG displayed significant differences between DVT patients and controls, indicating a hypercoagulable tendency in DVT patients. TEG also showed better capacity in identifying DVT than CCAs and had few correlations with CCA parameters.
CLINICA CHIMICA ACTA
(2021)
Article
Hematology
Esben Bjori, Hakon S. Johnsen, John-Bjarne Hansen, Sigrid K. Braekkan
THROMBOSIS RESEARCH
(2019)
Article
Hematology
Robin A. Liang, Ina I. Hoiland, Thor Ueland, Pal Aukrust, Omri Snir, Kristian Hindberg, Sigrid K. Braekkan, Peter Garred, Tom E. Mollnes, John-Bjarne Hansen
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2019)
Article
Hematology
Sara Lindstrom, Lu Wang, Erin N. Smith, William Gordon, Astrid van Hylckama Vlieg, Mariza de Andrade, Jennifer A. Brody, Jack W. Pattee, Jeffrey Haessler, Ben M. Brumpton, Daniel I. Chasman, Pierre Suchon, Ming-Huei Chen, Constance Turman, Marine Germain, Kerri L. Wiggins, James MacDonald, Sigrid K. Braekkan, Sebastian M. Armasu, Nathan Pankratz, Rebecca D. Jackson, Jonas B. Nielsen, Franco Giulianini, Marja K. Puurunen, Manal Ibrahim, Susan R. Heckbert, Scott M. Damrauer, Pradeep Natarajan, Derek Klarin, Paul S. de Vries, Maria Sabater-Lleal, Jennifer E. Huffman, Theo K. Bammler, Kelly A. Frazer, Bryan M. McCauley, Kent Taylor, James S. Pankow, Alexander P. Reiner, Maiken E. Gabrielsen, Jean-Francois Deleuze, Chris J. O'Donnell, Jihye Kim, Barbara McKnight, Peter Kraft, John-Bjarne Hansen, Frits R. Rosendaal, John A. Heit, Bruce M. Psaty, Weihong Tang, Charles Kooperberg, Kristian Hveem, Paul M. Ridker, Pierre-Emmanuel Morange, Andrew D. Johnson, Christopher Kabrhel, David-Alexandre Tregouet, Nicholas L. Smith, Emma Busenkell, Renae Judy, Julie Lynch, Michael Levin, J. H. Krishna Aragam, Mark Chaffin, Mary Haas, Themistocles L. Assimes, Jie Huang, Kyung Min Lee, Qing Shao, C. Kabrhel, Yunfeng Huang, Yan V. Sun, Marijana Vujkovic, Danish Saleheen, Donald R. Miller, Peter Reaven, Scott DuVall, William Boden, Saiju Pyarajan, Peter Henke, C. Kooperberg, J. Michael Gaziano, John Concato, Daniel J. Rader, Kelly Cho, Kyong-Mi Chang, Peter W. F. Wilson, Philip S. Tsao, Sekar Kathiresan, Andrea Obi
Article
Hematology
Benedikte Paulsen, Hanne Skille, Erin N. Smith, Kristian Hveem, Maiken E. Gabrielsen, Sigrid K. Braekkan, Frits R. Rosendaal, Kelly A. Frazer, Olga V. Gran, John-Bjarne Hansen
Letter
Hematology
Hanne Skille, Benedikte Paulsen, Kristian Hveem, Maiken E. Gabrielsen, Ben Brumpton, Kristian Hindberg, Olga V. Gran, Frits R. Rosendaal, Sigrid K. Braekkan, John-Bjarne Hansen
Article
Hematology
Trond Borvik, Sigrid K. Braekkan, Line H. Evensen, Ellen E. Brodin, Vania M. Morelli, Hasse Melbye, John-Bjarne Hansen
THROMBOSIS AND HAEMOSTASIS
(2020)
Review
Biochemistry & Molecular Biology
Vania M. Morelli, Sigrid K. Braekkan, John-Bjarne Hansen
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Hematology
Ellen-Sofie Hansen, Kristian Hindberg, Nadezhda Latysheva, Pal Aukrust, Thor Ueland, John-Bjarne Hansen, Sigrid K. Braekkan, Vania M. Morelli
Article
Hematology
Hanne Skille, Benedikte Paulsen, Kristian Hveem, Maiken E. Gabrielsen, Ben Brumpton, Kristian Hindberg, Olga V. Gran, Frits R. Rosendaal, Sigrid K. Braekkan, John-Bjarne Hansen
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2020)
Article
Cell Biology
Hakon S. Johnsen, Sigrid K. Braekkan, Vania M. Morelli, John-Bjarne Hansen
Summary: The study indicates that increasing platelet count in patients with VTE is associated with a higher risk of major bleeding. This association is observed not only with platelet count at VTE diagnosis, but also with platelet count measured on average 7 years before the thrombotic event.
Article
Hematology
Hakon S. Johnsen, Esben Bjori, Kristian Hindberg, Sigrid K. Braekkan, Vania M. Morelli, John-Bjarne Hansen
THROMBOSIS RESEARCH
(2020)
Article
Hematology
Fridtjof B. Rinde, Synne G. Fronas, Waleed Ghanima, Anders Vik, John-Bjarne Hansen, Sigrid K. Braekkan
THROMBOSIS RESEARCH
(2020)
Article
Hematology
Erin Mathiesen Hald, Maja-Lisa Lochen, Ellisiv B. Mathiesen, Tom Wilsgaard, Inger Njolstad, Sigrid K. Braekkan, John-Bjarne Hansen, Suzanne Cannegieter
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
(2020)
Article
Hematology
Joakim K. Sejrup, Vania M. Morelli, Maja-Lisa Lochen, Inger Njolstad, Ellisiv B. Mathiesen, Tom Wilsgaard, John-Bjarne Hansen, Sigrid K. Braekkan
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
(2020)
Article
Hematology
Trond Borvik, Line H. Evensen, Vania M. Morelli, Hasse Melbye, Sigrid K. Braekkan, John-Bjarne Hansen
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
(2020)