Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma

TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice

(2014) L. McKinley et al.   JOURNAL OF IMMUNOLOGY

T cells in asthma: Influences of genetics, environment, and T-cell plasticity

(2013) Clare M. Lloyd et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion

(2013) Alexandra M. Nanzer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peripheral Blood MDSCs, IL-10 and IL-12 in Children with Asthma and Their Importance in Asthma Development

(2013) Yan-Li Zhang et al.   PLoS One

Pediatric severe asthma is characterized by eosinophilia and remodeling without TH2 cytokines

(2012) Cara J. Bossley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction

(2012) Makoto Kudo et al.   NATURE MEDICINE

1α,25-Dihydroxyvitamin D3 promotes CD200 expression by human peripheral and airway-resident T cells

(2012) Sarah Dimeloe et al.   THORAX

Relationship between Serum Vitamin D, Disease Severity, and Airway Remodeling in Children with Asthma

(2011) Atul Gupta et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

WHO universal definition of severe asthma

(2011) Andrew Bush et al.   Current Opinion in Allergy and Clinical Immunology

Steroid Resistance in Severe Asthma: Current Mechanisms and Future Treatment

(2011) A Durham et al.   CURRENT PHARMACEUTICAL DESIGN

Human asthma phenotypes: from the clinic, to cytokines, and back again

(2011) Nirav R. Bhakta et al.   IMMUNOLOGICAL REVIEWS

Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome

(2011) Jan Lötvall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Involvement of IL-10 Gene Promoter Polymorphisms in the Susceptibility for Childhood Asthma

(2011) Kyung Won Kim et al.   LUNG

1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

(2011) S. Joshi et al.   MOLECULAR AND CELLULAR BIOLOGY

Interleukin (IL)-4, IL-13 and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients

(2011) A Bellini et al.   Mucosal Immunology

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resolution of Allergic Airway Inflammation and Airway Hyperreactivity Is Mediated by IL-17–producing γδT Cells

(2010) Jenna R. Murdoch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Expression of the T Helper 17-Associated Cytokines IL-17A and IL-17F in Asthma and COPD

(2010) Camille Doe et al.   CHEST

Cytokine Production by Peripheral Blood CD4+and CD8+T Cells in Atopic Childhood Asthma

(2010) Edyta Machura et al.   Clinical & Developmental Immunology

Management of severe asthma in children

(2010) Andrew Bush et al.   LANCET

1,25-Dihydroxyvitamin D3 Inhibits the Differentiation and Migration of TH17 Cells to Protect against Experimental Autoimmune Encephalomyelitis

(2010) Jae-Hoon Chang et al.   PLoS One

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The importance of nurse-led home visits in the assessment of children with problematic asthma

(2009) M Bracken et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Strategies for use of IL-10 or its antagonists in human disease

(2008) Anne O'Garra et al.   IMMUNOLOGICAL REVIEWS

Reference Ranges for Spirometry Across All Ages

(2007) Sanja Stanojevic et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE