Article
Respiratory System
Allison Martin Nguyen, Jonathan Schelfhout, David Muccino, Elizabeth D. Bacci, Carmen La Rosa, Margaret Vernon, Surinder S. Birring
Summary: This study assessed the psychometric properties of the Leicester Cough Questionnaire (LCQ) and found it to be a valid and reliable measure for evaluating cough-specific quality of life in patients with chronic cough. The results can guide treatment decisions and drug development, with a specific threshold increase in the LCQ total score considered as clinically meaningful change.
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE
(2022)
Article
Dermatology
Toni Maria Janke, Vlastimil Kozon, Skaidra Valiukeviciene, Laura Rackauskaite, Adam Reich, Katarzyna Stepien, Pavel Chernyshov, Monika Jankechova, Catherine van Montfrans, Stella Amesz, Marjam Barysch, Elena Conde Montero, Matthias Augustin, Christine Blome
Summary: This study validates the Wound-QoL-17 and Wound-QoL-14 versions for assessing health-related quality of life in patients with chronic wounds. Both versions demonstrated high internal consistency and moderate to good test-retest reliability. They showed significant correlations with global HRQoL rating, DLQI total score, and clinical data such as odor and wound size. The availability of multiple language versions makes these questionnaires suitable for international studies and clinical practice.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Psychology, Multidisciplinary
Hamed Savadkoohi, Salman Barasteh, Abbas Ebadi, Hadis Ashrafizadeh, Mahdi Akbarzadeh Amirdehi, Ali Safdari, Mohsen Mollahadi, Saeid Hossein Oghli
Summary: This study aimed to determine the psychometric properties of the Persian version of the wound-QOL questionnaire. The results showed that the Persian version of the wound-QOL questionnaire is a valid and reliable questionnaire, which can measure the QoL of patients with chronic wounds.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Medicine, General & Internal
Kian Fan Chung, Lorcan McGarvey, Woo-Jung Song, Anne B. Chang, Kefang Lai, Brendan J. Canning, Surinder S. Birring, Jaclyn A. Smith, Stuart B. Mazzone
Summary: Chronic cough is a prevalent and challenging condition with various underlying causes. It is associated with cough hypersensitivity, characterized by excessive coughing in response to stimuli, resulting in significant impact on patients' quality of life. Advances in understanding the mechanisms of cough hypersensitivity have led to the development of new therapies for chronic cough in adults. Personalized treatment approaches and phenotyping cough patients may hold promise for future management.
NATURE REVIEWS DISEASE PRIMERS
(2022)
Article
Medicine, General & Internal
Laura Quellhorst, Grit Barten-Neiner, Andres de Roux, Roland Diel, Pontus Mertsch, Isabell Pink, Jessica Rademacher, Sivagurunathan Sutharsan, Tobias Welte, Annegret Zurawski, Felix C. Ringshausen
Summary: This study validates the German translation of the QOL-B version 3.1 by providing psychometric validation using baseline data, showing good validity and test-retest reliability. The QOL-B scale effectively assesses the quality of life of patients with bronchiectasis.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, Research & Experimental
Cathy Y. Yu, Donna B. Jeffe, Margaret A. Kenna, John A. Germiller, Judith E. C. Lieu
Summary: A new parent-proxy Preschool Hearing Environments and Reflection on Quality of Life (HEAR-QL) questionnaire was developed and evaluated for children 2 to 6 years old with any hearing loss. The questionnaire was reduced to 23 items with five underlying factors: Behavior and Attention, Hearing Environments, New Social Situations, Social Interactions, and Communication. The study found moderate-to-strong correlations between each Preschool HEAR-QL factor and previously validated measures, supporting its construct validity. Discriminant validity testing requires a larger sample of children with normal hearing.
Article
Multidisciplinary Sciences
Isobel Sharpe, Sharon I. Kirkpatrick, Brendan T. Smith, Charles D. G. Keown-Stoneman, Jessica A. Omand, Shelley Vanderhout, Christine Warren, Jonathon L. Maguire, Catherine S. Birken, Laura N. Anderson
Summary: The study aimed to evaluate the relative validity of a short beverage screener (NHQ) compared to a 24-hour recall (ASA24) for assessing parent proxy-reported daily SCB intake among children. The results showed that parent proxy-reporting using the beverage screener can provide reasonable estimates of SCB intake when detailed dietary assessment is not feasible.
Article
Respiratory System
Allison Martin Nguyen, Elizabeth D. Bacci, Margaret Vernon, Surinder S. Birring, Carmen La Rosa, David Muccino, Jonathan Schelfhout
Summary: The cough severity Visual Analog Scale (VAS) is validated and responsive for assessing chronic cough severity, with a reduction of >30 mm on the VAS indicating clinically meaningful changes in chronic cough severity in clinical studies.
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE
(2021)
Article
Obstetrics & Gynecology
Rima Anggrena Dasrilsyah, Beng Kwang Ng, Ixora Kamisan Atan, Su-Yen Khong, Zalina Nusee, Pei Shan Lim
Summary: The translated Malay version of the P-QOL questionnaire has been validated as a reliable and consistent instrument for assessing the severity of symptoms and impact on quality of life among women with uterovaginal prolapse. It showed a significant correlation between domain scores and vaginal examination findings, as well as higher impact on quality of life with increasing POP-Q stage.
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2021)
Article
Medicine, General & Internal
Athanasios I. Tsirikos, Silvia Garcia-Martinez
Summary: This study examined the postoperative quality of life of 1354 patients with spinal deformity and found that patients with congenital scoliosis and Scheuermann kyphosis showed improved quality of life after more than 10 years of follow-up, while patients with other types of scoliosis or lumbosacral spondylolisthesis had poorer quality of life.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Allergy
Satoshi Morioke, Shunsuke Takahagi, Reo Kawano, Atsushi Fukunaga, Susumu Harada, Isao Ohsawa, Koji Masuda, Reiko Irifuku, Hitomi Yokobayashi, Yoshikazu Kameyoshi, Akio Tanaka, Saho Tamari, Michihiro Hide
Summary: The study confirmed the validity and reliability of the Japanese versions of the Angioedema Activity Score (AAS) and the Angioedema Quality of Life Questionnaire (AE-QoL) in assessing disease activity and health-related quality of life impairment in patients with recurrent angioedema (RecAE).
ALLERGOLOGY INTERNATIONAL
(2021)
Article
Respiratory System
Jonathan Schelfhout, Allison Martin Nguyen, Surinder S. Birring, Elizabeth D. Bacci, Margaret Vernon, David R. Muccino, Carmen La Rosa, Jaclyn A. Smith
Summary: The objective of this study was to explore the relationship between objective cough frequency and cough-specific patient-reported outcomes (PROs) and estimate a clinically meaningful change threshold (MCT) for objective cough frequency. The results showed significant but low to moderate correlations between 24-h cough frequency and cough-specific PROs. A >= 30% reduction in 24-h cough frequency was suggested as a reasonable MCT to define treatment response in chronic cough clinical trials.
Article
Respiratory System
Jennifer M. V. Mann, Anne E. Holland, Nicole S. L. Goh, Yet H. Khor
Summary: Chronic cough is a common and burdensome symptom in patients with interstitial lung disease (ILD). This study aimed to explore the characteristics and impacts of chronic cough in ILD patients. Patients experienced a spectrum of cough severity and characteristics, with physical, social, and emotional impacts contributing to symptom burden. Management strategies included various approaches such as medication, throat lozenges, and relaxation exercises. The findings highlight the need for further information and education on chronic cough in ILD patients.
Article
Allergy
Eli O. Meltzer, Robert S. Zeiger, Peter Dicpinigaitis, Jonathan A. Bernstein, John J. Oppenheimer, Nate A. Way, Vicky W. Li, Robert Boggs, Michael J. Doane, Eduardo Urdaneta, Jessica P. Weaver, Jonathan Schelfhout, Eileen Fonseca
Summary: This study investigated the prevalence of chronic cough and its impact on individuals and the healthcare system in the United States. Findings showed that individuals with chronic cough had lower health-related quality of life, increased anxiety and depression, impaired work productivity, sleep quality, and higher healthcare utilization compared to matched controls.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2021)
Article
Dermatology
Jin Liu, Huijuan Li, Peiying Zhang, Rui Bai, Xiaojin Fu, Hui Guan, Bing Wen, Yanming Ding, Xin Qi
Summary: We aimed to translate and validate the Wound-QoL-17 questionnaire for measuring the quality of life in Chinese patients with chronic wounds. Through various tests and analyses, we found that the Chinese version of Wound-QoL-17 showed good reliability and validity, and is suitable for evaluating the quality of life of patients with chronic wounds.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Respiratory System
Vikas Goyal, Anne B. Chang
CLINICS IN CHEST MEDICINE
(2022)
Article
Immunology
Gabrielle B. McCallum, Siew M. Fong, Keith Grimwood, Anna M. Nathan, Catherine A. Byrnes, Mong H. Ooi, Nachal Nachiappan, Noorazlina Saari, Peter S. Morris, Tsin W. Yeo, Robert S. Ware, Blueren W. Elogius, Victor M. Oguoma, Stephanie T. Yerkovich, Jessie de Bruyne, Katrina A. Lawrence, Bilawara Lee, John W. Upham, Paul J. Torzillo, Anne B. Chang
Summary: In children hospitalized with CAP, extending the antibiotic course was not superior to the standard course in achieving clinical cure at 4 weeks. Further research is needed to determine if an extended course provides longer-term benefits.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Article
Medicine, Research & Experimental
Taryn Jones, Kerry-Ann F. O'grady, Vikas Goyal, Ian B. Masters, Gabrielle McCallum, Christopher Drovandi, Thomas Lung, Emmah Baque, Denise S. K. Brookes, Caroline O. Terranova, Anne B. Chang, Stewart G. Trost
Summary: Bronchiectasis is a major cause of respiratory diseases, and children with the condition often experience exacerbations of their condition, leading to frequent hospitalizations and decreased quality of life. The BREATH trial aims to investigate the effects of a play-based therapeutic exercise program on exacerbation frequency, fitness, movement competence, and quality of life in children with bronchiectasis. The results of this trial have the potential to change the way therapeutic exercise is prescribed and implemented in children with chronic respiratory conditions.
Article
Pediatrics
Pamela Laird, Nicola Ball, Shekira Brahim, Henry Brown, Anne B. Chang, Matthew Cooper, Deanne Cox, Denetta Cox, Samantha Crute, Rachel E. Foong, Janella Isaacs, John Jacky, Gloria Lau, Elizabeth McKinnon, Annie Scanlon, Elizabeth F. Smith, Sarah Thomason, Roz Walker, Andre Schultz
Summary: This study found a high prevalence of protracted bacterial bronchitis, chronic suppurative lung disease, and bronchiectasis in Aboriginal children, with the prevalence of chronic wet cough increasing with age.
PEDIATRIC PULMONOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Wicharn Boonjindasup, Julie M. Marchant, Margaret S. McElrea, Stephanie T. Yerkovich, Rahul J. Thomas, Ian B. Masters, Anne B. Chang
Summary: There is limited data on spirometry curve patterns in children with tracheomalacia, but the presence of a convex inflection on flow-volume curves, known as the 'knee', is believed to indicate tracheomalacia. This study aimed to determine the prevalence of tracheomalacia in children with the 'knee' pattern and investigate if spirometry parameters and visual characteristics of the 'knee' can identify the presence and severity of tracheomalacia. The results showed that a majority of children with the 'knee' pattern had tracheomalacia, and those with tracheomalacia had lower spirometry values and a scoop before plateau was the most characteristic feature.
RESPIRATORY MEDICINE
(2022)
Article
Pediatrics
Taryn Jones, Emmah Baque, Kerry-Ann F. O'Grady, Vikas Goyal, Anne B. B. Chang, Stewart G. G. Trost
Summary: This study aimed to identify the factors that influence physical activity in children with bronchiectasis and determine facilitators and barriers to physical activity from the perspectives of both children and their parents. The study found that fun with friends, organized sport and activities, and family co-participation in physical activity were facilitators for children, while inability to keep up with peers and excessive use of technology were barriers. For parents, instrumental and logistic support, supportive social and physical activity environments were facilitators, while management of symptoms associated with bronchiectasis was a barrier.
FRONTIERS IN PEDIATRICS
(2022)
Article
Respiratory System
Annemarie L. Lee, Rebecca Smith, Lucy Burr, Anne B. Chang, Chien-Li Holmes-Liew, Paul King, Peter Middleton, Lucy Morgan, Daniel Smith, Rachel Thomson, Grant Waterer, Conroy Wong, Rachael McAleer
Summary: This study aimed to explore the perspectives of adults with bronchiectasis on relevant educational topics in a pulmonary rehabilitation context. The study found that people with bronchiectasis have a greater need for clarity on the underlying cause and prognosis of the condition. They also seek knowledge on self-management strategies, treatment options for extra-pulmonary symptoms, and information on physiotherapy and exercise outside of pulmonary rehabilitation.
CLINICAL RESPIRATORY JOURNAL
(2023)
Letter
Medicine, General & Internal
Keith Grimwood, Anne B. Chang
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Respiratory System
Anne B. Chang, Scott C. Bell, Catherine A. Byrnes, Paul Dawkins, Anne E. Holland, Emma Kennedy, Paul T. King, Pamela Laird, Sarah Mooney, Lucy Morgan, Marianne Parsons, Betty Poot, Maree Toombs, Paul J. Torzillo, Keith Grimwood
Summary: This position statement provides updated guidelines for the management of chronic suppurative lung disease (CSLD) and bronchiectasis in Australian and New Zealand children/adolescents and adults. The guidelines emphasize early diagnosis, using chest computed-tomography scans, and a baseline panel of investigations to assess severity and develop individualized management plans. Intensive treatment is recommended to improve symptom control and lung function, while individualized airway clearance techniques, regular exercise, and proper nutrition are also important. Exacerbations should be treated with appropriate antibiotics, and ongoing care and monitoring are crucial, especially for under-served populations.
Article
Respiratory System
Wicharn Boonjindasup, Julie M. Marchant, Margaret S. McElrea, Stephanie T. Yerkovich, Ian B. Masters, Anne B. Chang
Summary: This study aimed to evaluate the efficacy of routine spirometry in improving clinical decisions and patient-related outcome measures in pediatric respiratory practice. The results showed that compared to the control group, the intervention group had a higher proportion of children with changes in clinical decisions and higher clinical decision change scores. Furthermore, the intervention group also demonstrated improved patient anxiety levels and parent psychosocial well-being.
BMJ OPEN RESPIRATORY RESEARCH
(2023)
Article
Respiratory System
Amy S. Bleakley, Steven Kho, Michael J. Binks, Susan Pizzutto, Anne B. Chang, Jemima Beissbarth, Gabriela Minigo, Robyn L. Marsh
Summary: ETs in paediatric bronchiectasis can be detected using light microscopy-based assessment of Romanowsky-stained bronchoalveolar lavage slides. Neutrophil, macrophage, eosinophil, and lymphocyte ETs were observed, along with indeterminate ETs. Further research is needed to understand the potential clinical applications and therapies related to ETs in bronchiectasis.
Article
Medicine, General & Internal
Anne B. Chang, Richard S. Irwin, Hannah E. O'Farrell, Peter V. Dicpinigaitis, Suhani Goel, Ahmad Kantar, Julie M. Marchant
Summary: Chronic cough is a common symptom in children and adults, and there are specific management guidelines for children. The concept of 'cough hypersensitivity syndrome', which has gained attention in adult literature, may not be applicable to children due to significant differences in respiratory physiology and anatomy. This article explores the differences between childhood and adult chronic cough, explains cough hypersensitivity, and argues against its use in children.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Sami Azam, Sidratul Montaha, A. K. M. Rakibul Haque Rafid, Asif Karim, Mirjam Jonkman, Friso De Boer, Gabrielle McCallum, Ian Brent Masters, Anne Chang
Summary: Bronchiectasis in children can lead to severe lung conditions if not diagnosed and treated early. This study proposes an automated approach to detect and measure the broncho-arterial ratio using high-resolution computed tomography scans, which can assist in the diagnosis of bronchiectasis.
Article
Medicine, General & Internal
Julie M. Marchant, Anne B. Chang, Emma Kennedy, David King, Jennifer L. Perret, Andre Schultz, Maree R. Toombs, Lesley Versteegh, Shyamali C. Dharmage, Rebecca Dingle, Naomi Fitzerlakey, Johnson George, Anne Holland, Debbie Rigby, Jennifer Mann, Stuart Mazzone, Mearon Obrien, Kerry-Ann O'Grady, Helen L. Petsky, Jonathan Pham, Sheree M. S. Smith, Danielle F. Wurze, Anne E. Vertigan, Peter Wark
Summary: Cough is a common symptom that leads to doctor consultations, and chronic cough can result in significant healthcare costs and impair quality of life. Assessment should include a detailed history, examination, and necessary tests to identify underlying diseases. Different diagnostic algorithms should be followed for children and adults. First Nations adults and children should be considered at high risk.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Orthopedics
Susan L. Keays, Peter A. Newcombe, Joanne E. Bullock-Saxton, Anthony C. Keays
Summary: The high incidence of osteoarthritis (OA) in young sportspeople following anterior cruciate ligament (ACL) reconstruction surgery is concerning. This long-term study aimed to compare the incidence and severity of tibiofemoral OA (TFOA) and patellofemoral OA (PFOA) between reconstructed and non-reconstructed treatment groups and determine the factors that influence the development of OA.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
