Dual functionality ofO-GlcNAc transferase is required forDrosophiladevelopment

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

(2015) Shalini Pathak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

(2015) Shalini Pathak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

O-GlcNAcylation Prevents Aggregation of the Polycomb Group Repressor Polyhomeotic

(2014) Maria Cristina Gambetta et al.   DEVELOPMENTAL CELL

TMTC1 and TMTC2 Are Novel Endoplasmic Reticulum Tetratricopeptide Repeat-containing Adapter Proteins Involved in Calcium Homeostasis

(2014) Johan C. Sunryd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular architecture and mechanism of the anaphase-promoting complex

(2014) Leifu Chang et al.   NATURE

O-GlcNAcylation regulates EZH2 protein stability and function

(2014) C.-S. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase

(2013) M. B. Lazarus et al.   SCIENCE

O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

(2012) Shalini Pathak et al.   EMBO JOURNAL

Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery

(2012) Emanuele Bellacchio et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TET2 promotes histone O-GlcNAcylation during gene transcription

(2012) Qiang Chen et al.   NATURE

Structural snapshots of the reaction coordinate for O-GlcNAc transferase

(2012) Michael B Lazarus et al.   Nature Chemical Biology

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

(2012) Marianne Schimpl et al.   Nature Chemical Biology

Structural and Functional Discussion of the Tetra-Trico-Peptide Repeat, a Protein Interaction Module

(2012) Natalie Zeytuni et al.   STRUCTURE

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

O-GlcNAc Transferase Catalyzes Site-Specific Proteolysis of HCF-1

(2011) Francesca Capotosti et al.   CELL

GlcNAcylation of histone H2B facilitates its monoubiquitination

(2011) Ryoji Fujiki et al.   NATURE

Structure of human O-GlcNAc transferase and its complex with a peptide substrate

(2011) Michael B. Lazarus et al.   NATURE

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

(2011) Tracey M Gloster et al.   Nature Chemical Biology

Drosophila melanogaster dHCF Interacts with both PcG and TrxG Epigenetic Regulators

(2011) Sara Rodriguez-Jato et al.   PLoS One

Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells

(2011) S. A. Myers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development

(2009) Danielle M Webster et al.   BMC DEVELOPMENTAL BIOLOGY

Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc)

(2009) D. A. R. Sinclair et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of the Glycosyltransferase Sxc/Ogt in Polycomb Repression

(2009) Maria Cristina Gambetta et al.   SCIENCE

Structural insights into mechanism and specificity of O-GlcNAc transferase

(2008) Andrew J Clarke et al.   EMBO JOURNAL

AMP-activated Protein Kinase and p38 MAPK ActivateO-GlcNAcylation of Neuronal Proteins during Glucose Deprivation

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE

Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation

(2008) Carlos Martinez-Fleites et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY