Article
Nutrition & Dietetics
Xuefei Li, Zhengjie Lu, Yongjian Qi, Biao Chen, Bin Li
Summary: This study used the Mendelian randomization approach to explore the potential causal relationships between polyunsaturated fatty acids (PUFAs) and osteoarthritis (OA), and found that higher levels of omega-6 fatty acids may reduce the risk of knee OA and hip OA. These results highlight the importance of maintaining optimal levels of PUFAs, especially omega-6 fatty acids, in individuals with a genetic predisposition to OA.
Article
Obstetrics & Gynecology
J. Stanhiser, A. M. Z. Jukic, D. R. McConnaughey, A. Z. Steiner
Summary: The study found that self-reported use of omega-3 fatty acid supplements was associated with an increased probability of conceiving.
HUMAN REPRODUCTION
(2022)
Article
Geriatrics & Gerontology
Roxana Coras, Brian Pedersen, Rekha Narasimhan, Anahy Brandy, Lourdes Mateo, Agueda Prior-Espanol, Arthur Kavanaugh, Aaron M. Armando, Mohit Jain, Oswald Quehenberger, Melania Martinez-Morillo, Monica Guma
Summary: The study revealed that arthritis symptoms in older adults were related to disturbances in serum oxylipins, suggesting that certain oxylipins may be key effectors in arthritis in this population.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Nutrition & Dietetics
Kathleen A. Lee-Sarwar, Kasper Fischer-Rasmussen, Klaus Bonnelykke, Hans Bisgaard, Bo Chawes, Rachel S. Kelly, Jessica Lasky-Su, Robert S. Zeiger, George T. O'Connor, Leonard B. Bacharier, Vincent J. Carey, Nancy Laranjo, Augusto A. Litonjua, Scott T. Weiss
Summary: The association between omega-3 fatty acids (n-3) and allergic diseases varies due to genetic variation. This study aimed to identify and validate genetic variants that modify the relationship between n-3 and childhood asthma or atopy. Results showed that certain SNPs in the DPP10 region interacted with n-3 levels in plasma or diet and were associated with atopy in early childhood and at age 6.
Review
Biochemistry & Molecular Biology
Roberta Cardim Lessa, Fabio de Abreu Alves, Erika Fortunati, Jun Lu
Summary: Oral mucositis (OM) is a painful condition caused by cancer treatments, impacting patients' quality of life and recovery. Current management strategies are insufficient, necessitating a search for new approaches. Utilizing ω-3 fatty acids to manage OM may be an effective strategy based on preliminary evidence.
Article
Agricultural Engineering
Anil Kumar Patel, Ajeet Singh Chauhan, Prashant Kumar, Philippe Michaud, Vijai Kumar Gupta, Jo-Shu Chang, Chiu-Wen Chen, Cheng-Di Dong, Reeta Rani Singhania
Summary: This article provides an update on the production of essential fatty acids from potential microbes and explores novel strategies to promote the accumulation of omega-3 and omega-6 through engineering and omics approaches.
BIORESOURCE TECHNOLOGY
(2022)
Article
Nutrition & Dietetics
Marco Ugo Andrea Sartorio, Erica Pendezza, Serena Coppola, Lorella Paparo, Enza D'Auria, Gian Vincenzo Zuccotti, Roberto Berni Canani
Summary: Polyunsaturated fatty acids (PUFAs) may have potential beneficial effects on the prevention and treatment of pediatric food allergy, but there is still a lack of consistent clinical data to determine the optimal timing, dosage, and individuals most likely to benefit.
Article
Nutrition & Dietetics
Estefania Aparicio, Carla Martin-Grau, Cristina Bedmar, Nuria Serrat Orus, Josep Basora, Victoria Arija
Summary: This study found that factors such as high education levels, older age, consumption of fish and seafood, and non-smoking are significantly associated with serum fatty acid concentrations in pregnant women, leading to a better omega-3 fatty acid profile. Further research is needed to explore the health consequences of these findings.
Review
Food Science & Technology
Yi Wang, Ke Liu, Tingting Long, Jieyi Long, Ying Li, Jiaoyuan Li, Liming Cheng
Summary: Through a meta-analysis of observational studies, we found that dietary fish and marine omega-3 PUFA consumption are associated with improved cancer prognosis and reduced mortality in patients.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Nutrition & Dietetics
Masayuki Okuda, Aya Fujiwara, Satoshi Sasaki
Summary: The study found that in Japanese youths, high intake of omega-6 polyunsaturated fatty acids was associated with low levels of low-density-lipoprotein cholesterol, while high intake of saturated fatty acids was associated with high levels of gamma-glutamyl transpeptidase, indicating a close relationship between dietary fatty acid composition and cardiometabolic risk.
Article
Biochemistry & Molecular Biology
Claudia Sanfilippo, Angela Patti
Summary: The biocatalytic epoxidation of ethanolamides of omega-3 fatty acids EPA and DHA was investigated in the presence of a peroxygenase-containing preparation from oat flour. Good regio- and steroselectivity were observed, and acetone as cosolvent improved the concentration of starting substrates and selectivity in the epoxidation of DHA-EA. This method offers a valuable strategy for obtaining oxyfunctionalized derivatives of fatty acids due to the easy availability of the enzymatic preparation.
BIOORGANIC CHEMISTRY
(2021)
Article
Nutrition & Dietetics
Flavia M. S. De Branco, Ana Elisa M. Rinaldi, Jaqueline L. Pereira, Hamilton Roschel, Catarina M. Azeredo, Erick P. De Oliveira
Summary: This study evaluated the association between plasma omega-3 (6)-3 fatty acids and appendicular muscle mass index (AMMI) in adults, taking into account protein intake. The results showed a positive correlation between plasma omega-3 (6)-3 fatty acids and AMMI in individuals with low protein intake, indicating potential benefits of omega-3 (6)-3 fatty acid supplementation for muscle mass when protein intake is inadequate.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Qi Sun, Ning Gao, Weiliang Xia
Summary: This study found a negative correlation between omega-3 and omega-6 levels and the risk of cholelithiasis. Individuals with low serum omega-3/6 levels should be aware of the risk of cholelithiasis.
FRONTIERS IN NUTRITION
(2022)
Article
Biotechnology & Applied Microbiology
Myroslav Sprynskyy, Fernanda Monedeiro, Maciej Monedeiro-Milanowski, Zuzanna Nowak, Aneta Krakowska-Sieprawska, Pawel Pomastowski, Renata Gadzala-Kopciuch, Boguslaw Buszewski
Summary: This study aimed to isolate EPA and DHA from diatom biomass using different extraction methods and analyze the extracts. Reflux extraction yielded the highest content of omega-3 fatty acids, while the extracts obtained from SFE had lower toxicity and could be directly used for product development.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Endocrinology & Metabolism
Lin Wang, Chao Zhang, Hao Liang, Nian Zhou, Tianji Huang, Zenghui Zhao, Xiaoji Luo
Summary: This study using Mendelian randomization analysis found a causal relationship between omega-6 fatty acids and bone mineral density. Further research is needed to elucidate the underlying mechanism.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Juan M. Toledano, Jorge Moreno-Fernandez, Maria Puche-Juarez, Julio J. Ochoa, Javier Diaz-Castro
Summary: Since the emergence of COVID-19, finding preventive and therapeutic options has become a priority. The approval of vaccines is crucial, but there is still a need to study alternative methods to support the immune system. Adequate nutrition and vitamin intake can improve immune response and prevent infection.
Article
Biochemistry & Molecular Biology
Jorge Moreno-Fernandez, Julio J. Ochoa, Catalina De Paco Matallana, Africa Cano, Estefania Martin-Alvarez, Javier Sanchez-Romero, Juan M. Toledano, Maria Puche-Juarez, Sonia Prados, Susana Ruiz-Duran, Lucia Diaz-Meca, Maria Paz Carrillo, Javier Diaz-Castro
Summary: COVID-19 infection during pregnancy can lead to decreased serum antioxidant capacity in mothers and alterations in placental iron metabolism. Further research is required to understand the pathogenic mechanisms and outcomes in maternal and infant health.
Article
Nutrition & Dietetics
Maria Luisa Ojeda, Fatima Nogales, Olimpia Carreras, Eloisa Pajuelo, Maria Del Carmen Gallego-Lopez, Ines Romero-Herrera, Belen Begines, Jorge Moreno-Fernandez, Javier Diaz-Castro, Ana Alcudia
Summary: This study investigates the effects of low-dose selenite and Se nanoparticles on adipose tissue deposition and insulin secretion in adolescent rats. The results show that low selenite supplementation promotes adipogenesis, while Se nanoparticle administration prevents fat depots and inflammation.
Editorial Material
Nutrition & Dietetics
Jorge Moreno-Fernandez, Julio J. Ochoa, Maria Luisa Ojeda, Javier Diaz-Castro
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Gladys O. Latunde-Dada, Naroa Kajarabille, Sophie Rose, Sarah M. Arafsha, Tugba Kose, Mohamad F. Aslam, Wendy L. Hall, Paul A. Sharp
Summary: With the increasing popularity of plant-based diets, there is a growing interest in evaluating the nutritional value of meat substitutes. Understanding the mineral content and absorption of these products is crucial as plant-based eating becomes more common. This study aimed to analyze the mineral composition and uptake of plant-based meat-free burgers compared to a typical beef burger.
Article
Biochemistry & Molecular Biology
Jorge Moreno-Fernandez, Maria Puche-Juarez, Juan M. Toledano, Ignacio Chirosa, Luis J. Chirosa, Mario Pulido-Moran, Naroa Kajarabille, Isabel M. Guisado, Rafael Guisado, Javier Diaz-Castro, Julio J. Ochoa
Summary: This study aimed to evaluate the potential positive effects of ubiquinol supplementation on muscle aggression, physical performance, and fatigue perception in non-elite athletes after high intensity circuit weight training. The results showed that ubiquinol supplementation improved muscle performance, reduced muscle damage markers, and had a protective effect on muscle fibers.
Review
Biochemistry & Molecular Biology
Juan M. Toledano, Maria Puche-Juarez, Jorge Moreno-Fernandez, Julio J. Ochoa, Javier Diaz-Castro
Summary: Since the COVID-19 pandemic is ongoing, exploring strategies to support the immune system during infection is necessary. An adequate diet can improve immune responses, and minerals, which have immune-modulatory and antioxidant activities, might be useful in fighting this illness. Although more research is needed, evidence from studies on respiratory diseases suggests the rationality of investigating the use of minerals during this pandemic.
Review
Medicine, General & Internal
Maria Puche-Juarez, Juan M. Toledano, Julio J. Ochoa, Javier Diaz-Castro, Jorge Moreno-Fernandez
Summary: Background: Obesity and being overweight have become severe global health issues. Maternal dietary habits and other factors during pregnancy can have a significant impact on the prevention of obesity in children. A review of recent human studies aims to determine modifiable factors that influence adiposity and prevent specific disorders later in life. Conclusion: A healthy diet and lifestyle starting from pregnancy and throughout childhood, particularly in the first two years, can prevent the emergence of noncommunicable diseases and metabolic syndrome-related pathologies.
Review
Nutrition & Dietetics
Maria Puche-Juarez, Juan M. Toledano, Jorge Moreno-Fernandez, Yolanda Galvez-Ontiveros, Ana Rivas, Javier Diaz-Castro, Julio J. Ochoa
Summary: Endocrine disrupting chemicals (EDCs) are exogenous substances that can interfere with the regulation and function of the endocrine system, potentially causing serious health effects, especially on pregnant women and fetuses. It is important to conduct further research on the health issues caused by these substances and implement preventive measures.
Article
Neurosciences
Ines Romero-Herrera, Fatima Nogales, Maria del Carmen Gallego-Lopez, Javier Diaz-Castro, Jorge Moreno-Fernandez, Julio Jose Ochoa, Olimpia Carreras, Ma Luisa Ojeda
Summary: This study analyzed the effects of binge drinking on white adipose tissue in adolescent rats. The results showed that binge drinking led to oxidative imbalance and insulin resistance, altering the energy balance in the adipose tissue and affecting adipokine secretion, contributing to the development of metabolic and endocrine disruption.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)