Article
Pediatrics
Pin Li, Huixia Zhou, Hualin Cao, Tao Guo, Weiwei Zhu, Yang Zhao, Tian Tao, Xiaoguang Zhou, Lifei Ma, Yunjie Yang, Zhichun Feng
Summary: Robotic-assisted laparoscopic pyeloplasty (RALP) is a safe and feasible option for treating severe ureteropelvis junction obstruction (UPJO) in infants under 3 months, with significant renal function recovery observed in all patients within 12 months post-operation.
FRONTIERS IN PEDIATRICS
(2021)
Review
Pediatrics
Vijaya M. Vemulakonda
Summary: Ureteropelvic junction obstruction (UPJO) is a common cause of prenatal diagnosed hydronephrosis, with recent studies focusing on the use of ultrasound classification systems and MRI to stratify the risk in infants. Urinary biomarkers have also shown potential as a noninvasive alternative in identifying infants with clinically significant UPJO. Further research is needed to establish clear guidelines for evaluation and treatment to improve long-term outcomes for these patients.
CURRENT OPINION IN PEDIATRICS
(2021)
Review
Pediatrics
Geminiganesan Sangeetha, Ramesh Babu
Summary: This meta-analysis compared the accuracy of common urinary biomarkers for ureteropelvic junction obstruction (UPJO) and found that CA 19-9 had the highest sensitivity, NGAL had the highest specificity, and CA 19-9 had the highest overall accuracy.
PEDIATRIC NEPHROLOGY
(2022)
Article
Urology & Nephrology
Jun Liu, Jingjun Zhang, Weinan Chen, Liulin Xiong, Xiaobo Huang, Xiongjun Ye
Summary: This study compared the effects of two different methods of laparoscopic pyeloplasty for treating crossing vessels in patients with ureteropelvic junction obstruction. Results showed that both the Hem-o-lok suspension and vascular transposition methods effectively relieved crossing vessel compression, improving the success of the surgery without significant changes in kidney size or hydronephrosis post-operation.
Article
Pediatrics
Mahgol Sadghian, Seyed Abdollah Mousavi, Seyed Mohammad Abedi, Mahboubeh JafariSarouei, Maedeh Gooran, Paniz Balmeh, Hamid Mohammadjafari
Summary: Ureteropelvic junction obstruction (UPJO) is a common urologic problem in children, and it can be treated with either surgical or observational approaches. This study found that conservative management is as effective as early surgical treatment for infants with severe UPJO.
PEDIATRIC SURGERY INTERNATIONAL
(2023)
Review
Medicine, General & Internal
Daisuke Tamura, Shintaro Narita, Misa Yamauchi, Rina Watanabe, Shota Yokoyama, Akane Kikuchi, Akihiro Shitara, Syuji Chiba, Fumiko Saito, Akihiro Sugita, Kazunari Sato, Akihiro Karube
Summary: This article reports a case of giant hydronephrosis associated with ureteropelvic junction obstruction detected during pregnancy, which was treated conservatively and underwent surgical treatment after delivery, and provides a literature review on the related topics.
Article
Urology & Nephrology
Vijaya M. Vemulakonda, Carter Sevick, Elizabeth Juarez-Colunga, George Chiang, Nicolette Janzen, Alison Saville, Parker Adams, Gemma Beltran, Jordon King, Emily Ewing, Allison Kempe
Summary: The study revealed variations in infant pyeloplasty rates among different healthcare sites. Prolonged T1/2 was associated with surgery, despite prior studies indicating its poor predictive value for worsening dilation or function. These findings suggest the necessity to standardize evaluation and intervention indications in infants with suspected UPJ obstruction.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2021)
Article
Medicine, Research & Experimental
Qi-Fei Deng, Han Chu, Bo Peng, Xiang Liu, Yong-Sheng Cao
Summary: This study found that early surgical treatment (EST) can accelerate the recovery of renal morphological and functional indices in neonates and infants with severe hydronephrosis. Compared with conservative treatment (CT), the EST group showed significantly reduced anteroposterior diameter of the renal pelvis and Society of Fetal Urology grade at 3 and 6 months of follow-up, and greater thickness of the renal cortex, with significantly improved renal function after 6 months of follow-up.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2021)
Article
Pediatrics
Noah Stern, Yilong Li, Peter (Zhantao) Wang, Sumit Dave
Summary: This study investigates the learning curve of transitioning from laparoscopic to robot-assisted pyeloplasty (RAP) by analyzing the total and step-specific operative times. The findings suggest that surgeons can achieve a significant decrease in total operative time after performing approximately 30 RAP procedures. The complication rate remains within acceptable limits, indicating that RAP can be safely adopted even in low volume centers.
JOURNAL OF PEDIATRIC UROLOGY
(2022)
Article
Pediatrics
Aaron J. Krill, Briony K. Varda, Nicholas A. Freidberg, Md Sohel Rana, Eglal Shalaby-Rana, Bruce M. Sprague, Hans G. Pohl
Summary: Refined sub-stratification of indeterminate T1/2 intervals in MAG3 diuresis renography can better predict the need for future pyeloplasty and provide more accurate prognostic information in infants and young children with hydronephrosis.
JOURNAL OF PEDIATRIC UROLOGY
(2021)
Article
Medicine, General & Internal
S. Ozaydin, S. Celebi
Summary: Patients with left-side ureteropelvic junction obstructions have a more severe course compared to those with right-side obstructions. Preoperative kidney function declined in the left-side group while it improved in the right-side group.
NIGERIAN JOURNAL OF CLINICAL PRACTICE
(2022)
Article
Biotechnology & Applied Microbiology
Shaokai Zheng, Pedro Amado, Dominik Obrist, Fiona Burkhard, Francesco Clavica
Summary: In this study, a simple in vitro bladder model was designed to simulate the dynamics of filling and voiding. The physio-mechanical condition of the model was verified using pressure-flow and reflux tests. Encrustation tests with artificial urine on double-J stents were conducted using the model, and the volumes of luminal encrustations were quantified. The results suggest that VUR is an important factor contributing to the dynamics in the upper urinary tract with indwelling stents, emphasizing its significance in future in vitro studies and clinical analyses.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Editorial Material
Pediatrics
Jennifer M. Lovin, Andrew J. Kirsch, Shuvro De
Summary: A case of a right parapelvic renal cyst causing intermittent UPJO was successfully treated with robotic cyst decortication, highlighting the importance of clinical suspicion and appropriate imaging for diagnosis. The patient experienced resolution of hydronephrosis and parapelvic cyst after surgery, demonstrating the effectiveness of this approach.
JOURNAL OF PEDIATRIC UROLOGY
(2021)
Article
Medicine, General & Internal
Vladimir V. Sizonov, Askhab H-A Shidaev, Johannes M. Mayr, Mikhail Kogan, Ilya M. Kagantsov, Vera V. Rostovskaya
Summary: The study compared the outcomes of Anderson-Hynes pyeloplasty and a new technique in treating pediatric patients with ureteropelvic junction obstruction caused by renal lower pole crossing vessels. Results showed similar effectiveness of both methods at 12 months postoperatively, with no significant differences in outcomes.
Article
Engineering, Biomedical
Jihun Lee, Jaebum Sung, Jung Ki Jo, Hongyun So
Summary: This paper presents novel umbrella-shaped flexible devices for preventing vesicoureteral reflux, particularly in patients with urinary stones. The devices mechanically attach to the stent and have been shown to be effective through experiments. The penta-shaped device exhibited the best anti-reflux performance, with maximum efficiency achieved when attached at a specific location.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2022)