期刊
TETRAHEDRON-ASYMMETRY
卷 19, 期 18, 页码 2149-2152出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2008.09.006
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The first enantioselective Michael addition of aniline to chalcones was promoted by cheap and commercially available chincona alkaloids under solvent-free conditions. Variously substituted chalcones were examined as substrates giving the conjugate adducts in moderate to good enantioselectivity. The simple experimental procedure had no work-up and short reaction times, which are the notable advantages. (C) 2008 Elsevier Ltd. All rights reserved.
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