期刊
TETRAHEDRON LETTERS
卷 55, 期 29, 页码 3979-3983出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.05.017
关键词
Ring opening of epoxides; Alcoholysis; Methanolysis; Fe(Cp)(2)BF4; Lewis acid catalyst
资金
- University of Delhi under Research and Development grant
- University Science Instrumentation Centre (USIC), University of Delhi, India
Fe(Cp)(2)BF4 is an efficient catalyst for the alcoholysis of aromatic, aliphatic, and cyclic epoxides giving excellent yields of the corresponding beta-alkoxy alcohols under ambient conditions. The methanolysis of styrene oxide using Fe(Cp)(2)BF4 as a catalyst (5 mol %) gave excellent yield of 2-methoxy-2-phenylethanol with complete regio-selectivity. The ring opening of cyclic epoxides gave 77-97% yields of trans-beta-methoxy alcohols, in 0.5-6 h. The use of 1,2-epoxyhexane and 1,2-epoxydodecane as substrates gave both regioisomers in excellent yields. The first order rate of reaction with respect to catalyst was observed for the kinetics of ring opening of 1,2-epoxyhexane with methanol. (C) 2014 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据